Pre_GI: BLASTP Hits

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Query: NC_017160:4073611:4081370 Yersinia pestis D182038 chromosome, complete genome

Start: 4081370, End: 4081741, Length: 372

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010552:2089140:210195221019522102374423Burkholderia ambifaria MC40-6 chromosome 2, complete sequenceDomain of unknown function DUF17953e-1684
NC_008061:428501:432922432922433344423Burkholderia cenocepacia AU 1054 chromosome 2, complete sequencehypothetical protein6e-1786.3
NC_008543:2035292:204632220463222046744423Burkholderia cenocepacia HI2424 chromosome 2, complete sequencehypothetical protein6e-1786.3
NC_011001:2517159:252962125296212530043423Burkholderia cenocepacia J2315 chromosome 2, complete sequencehypothetical protein1e-1788.6
NC_010515:2358134:236254423625442362966423Burkholderia cenocepacia MC0-3 chromosome 2, complete sequenceDomain of unknown function DUF17956e-1786.3
NC_012962:3463644:349409334940933494542450Photorhabdus asymbiotica, complete genomehypothetical protein4e-26116
NC_003296:1419992:143704214370421437473432Ralstonia solanacearum GMI1000 plasmid pGMI1000MP, completehypothetical protein3e-1683.6
NC_014310:1413210:143561514356151436037423Ralstonia solanacearum PSI07 megaplasmid, complete sequencehypothetical protein3e-1684
NC_013892:274297:293690293690294145456Xenorhabdus bovienii SS-2004 chromosome, complete genomehypothetical protein1e-23108
NC_014228:3353896:336192533619253362380456Xenorhabdus nematophila ATCC 19061, complete genomehypothetical protein4e-23106
NC_017168:1631052:165275016527501653172423Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-67254
NC_005810:4469156:447710844771084477530423Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-67254
NC_004088:266543:274302274302274724423Yersinia pestis KIM, complete genomehypothetical protein1e-67254
NC_008149:4053363:406112240611224061544423Yersinia pestis Nepal516, complete genomehypothetical protein1e-67254
NC_010634:4234932:424255442425544242976423Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein1e-67254