Pre_GI: BLASTP Hits

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Query: NC_017160:2740870:2754739 Yersinia pestis D182038 chromosome, complete genome

Start: 2754739, End: 2755929, Length: 1191

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005810:2613456:2617730261773026189651236Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0821
NC_004088:1801819:1817276181727618185111236Yersinia pestis KIM, complete genomehypothetical protein0821
NC_003143:2849377:2853651285365128548411191Yersinia pestis CO92, complete genomehypothetical protein0820
NC_008149:2411161:2415465241546524166551191Yersinia pestis Nepal516, complete genomehypothetical protein0820
NC_010159:1861465:1865732186573218669221191Yersinia pestis Angola, complete genomehypothetical protein0820
NC_017154:3139614:3155116315511631563061191Yersinia pestis D106004 chromosome, complete genomehypothetical protein0820
NC_017168:2892000:2907595290759529087851191Yersinia pestis A1122 chromosome, complete genomehypothetical protein0820
NC_017265:1521276:1538388153838815395781191Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0820
NC_009708:1694685:1708769170876917099621194Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein0768
NC_010465:1724000:1740149174014917412281080Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein8e-169593
NC_010634:2960000:2962933296293329642011269Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein6e-134477
NC_006155:3040769:3045035304503530463031269Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein6e-134477
NC_008800:1497746:1512494151249415138341341Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein2e-32140