Pre_GI: BLASTP Hits

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Query: NC_017160:2362002:2398860 Yersinia pestis D182038 chromosome, complete genome

Start: 2398860, End: 2399294, Length: 435

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010634:1916000:191750519175051918431927Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein5e-82301
NC_006155:1916426:191752119175211918447927Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein5e-82301
NC_005810:1794490:179578417957841796338555Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-81300
NC_016845:3448881:346487434648743465800927Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,hypothetical protein2e-81300
NC_009381:1362471:139660513966051397159555Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-81300
NC_004088:2640440:267720426772042677758555Yersinia pestis KIM, complete genomehypothetical protein2e-81300
NC_003143:2137945:213904021390402139594555Yersinia pestis CO92, complete genomehypothetical protein2e-81300
NC_008150:1420825:142211914221191422673555Yersinia pestis Antiqua, complete genomehypothetical protein2e-81300
NC_010159:2164500:216575121657512166185435Yersinia pestis Angola, complete genomeyp42; ORF 74, len5e-81298
NC_017154:2137500:213860821386082139042435Yersinia pestis D106004 chromosome, complete genomeyp425e-81298
NC_012731:3411161:342715534271553428081927Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomehypothetical protein5e-81298
NC_014500:3097362:312943531294353130361927Dickeya dadantii 3937 chromosome, complete genomehypothetical protein1e-41168
NC_011283:1811000:185368618536861854603918Klebsiella pneumoniae 342 chromosome, complete genomehypothetical protein4e-40162
NC_013421:1819036:184201518420151842929915Pectobacterium wasabiae WPP163, complete genomehypothetical protein6e-40162
NC_013592:1668092:167299016729901673916927Dickeya dadantii Ech586, complete genomehypothetical protein1e-38157
NC_017047:2079368:208488220848822085808927Rahnella aquatilis HX2 chromosome, complete genomehypothetical protein8e-38155
NC_013592:2968500:299268229926822993596915Dickeya dadantii Ech586, complete genomehypothetical protein2e-37154
NC_012912:1701231:172714717271471728073927Dickeya zeae Ech1591, complete genomehypothetical protein3e-37153
NC_009792:3225965:324162432416243242196573Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein8e-2199
NC_009648:5119271:514121051412105142100891Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomehypothetical protein2e-1994.4
NC_012731:600518:627525627525628415891Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomehypothetical protein2e-1994.4