Pre_GI: BLASTP Hits

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Query: NC_017160:2362002:2393024 Yersinia pestis D182038 chromosome, complete genome

Start: 2393024, End: 2393761, Length: 738

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017154:2137500:214414121441412144944804Yersinia pestis D106004 chromosome, complete genomeyersiniabactin biosynthetic protein YbtT1e-134478
NC_005810:1794490:180131718013171802120804Yersinia pestis biovar Microtus str. 91001, complete genomeyersiniabactin biosynthetic protein YbtT1e-134478
NC_010634:1916000:192303719230371923840804Yersinia pseudotuberculosis PB1/+, complete genomethioesterase1e-134478
NC_010159:2164500:217128421712842172087804Yersinia pestis Angola, complete genomeyersiniabactin biosynthesis thioesterase YbtT1e-134478
NC_003143:2137945:214457321445732145376804Yersinia pestis CO92, complete genomeyersiniabactin biosynthetic protein YbtT1e-134478
NC_008150:1420825:142765214276521428440789Yersinia pestis Antiqua, complete genomeyersiniabactin biosynthetic protein YbtT3e-134477
NC_006155:1916426:192305319230531923841789Yersinia pseudotuberculosis IP 32953, complete genomeyersiniabactin biosynthetic protein YbtT3e-134477
NC_009381:1362471:139083813908381391626789Yersinia pestis Pestoides F chromosome, complete genomeyersiniabactin biosynthetic protein YbtT3e-134477
CU928145:2237099:225878722587872259590804Escherichia coli 55989 chromosome, complete genomeputative thioesterase YbtT3e-133474
NC_011748:2237099:225878722587872259590804Escherichia coli 55989, complete genomeputative thioesterase YbtT3e-133474
NC_008563:2094855:211654121165412117344804Escherichia coli APEC O1, complete genomeyersiniabactin biosynthetic protein YbtT3e-133474
NC_011742:2002526:202421420242142025017804Escherichia coli S88 chromosome, complete genomethioesterase YbtT3e-133474
NC_013361:2757168:277884727788472779650804Escherichia coli O26:H11 str. 11368 chromosome, complete genomesiderophore biosynthetic protein3e-133474
NC_012731:3411161:342174634217463422549804Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeyersiniabactin biosynthetic protein2e-133474
NC_011750:1134721:113630211363021137105804Escherichia coli IAI39 chromosome, complete genomeputative thioesterase YbtT6e-133473
NC_007946:2074098:209580120958012096589789Escherichia coli UTI89, complete genomeYbtT protein6e-133473
NC_008253:1938975:199708219970821997870789Escherichia coli 536, complete genomeyersiniabactin biosynthetic protein YbtT6e-133473
NC_011751:2281653:230334123033412304144804Escherichia coli UMN026 chromosome, complete genomeputative thioesterase YbtT6e-133473
CP002797:2025330:204702820470282047831804Escherichia coli NA114, complete genomeyersiniabactin biosynthetic protein5e-133473
NC_011745:2168379:219006721900672190870804Escherichia coli ED1a chromosome, complete genomeputative thioesterase YbtT4e-133473
NC_016845:3448881:345953234595323460269738Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,putative thioesterase YbtT8e-133472
NC_008800:2806827:283703328370332837836804Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,yersiniabactin biosynthetic protein YbtT2e-128458
NC_004088:2640440:267156926715692672225657Yersinia pestis KIM, complete genomeyersiniabactin thioesterase7e-118422
NC_004431:2185750:224476222447622245418657Escherichia coli CFT073, complete genomePutative thioesterase5e-117420
NC_008786:2729635:275179527517952752568774Verminephrobacter eiseniae EF01-2, complete genomeThioesterase7e-56217
NC_012962:2587756:263570926357092636515807Photorhabdus asymbiotica, complete genomeyersiniabactin synthetase, thioesterase component1e-50199
NC_010572:188500:204852204852205616765Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative thioesterase1e-25116
NC_007651:2639553:265570726557072656543837Burkholderia thailandensis E264 chromosome I, complete sequencethioesterase type II5e-23108
NC_012471:1197534:123199012319901232739750Streptococcus equi subsp. equi 4047, complete genomenon-ribosomal peptide synthesis thioesterase type II1e-22107
NC_016582:4934854:493781649378164938577762Streptomyces bingchenggensis BCW-1 chromosome, complete genomethioesterase1e-21103
NC_016111:134444:1447761447761457951020Streptomyces cattleya NRRL 8057, complete genomeThioesterase6e-21100
NC_002944:4163490:418032641803264181078753Mycobacterium avium subsp. paratuberculosis K-10, complete genomehypothetical protein5e-2098.2
NC_009725:2859630:288522328852232885927705Bacillus amyloliquefaciens FZB42, complete genomeNrsA3e-1995.5
NC_009848:354202:362404362404363144741Bacillus pumilus SAFR-032, complete genomethioesterase4e-1995.1
NC_011725:2365647:238805123880512388773723Bacillus cereus B4264 chromosome, complete genomethioesterase2e-1893.2
NC_010180:213825:218356218356219078723Bacillus weihenstephanensis KBAB4 plasmid pBWB401, completeOleoyl-(acyl-carrier-protein) hydrolase2e-1892.8
NC_020126:5777895:579371557937155794500786Myxococcus stipitatus DSM 14675, complete genomethioesterase domain-containing protein6e-1891.3
NC_015738:3042000:305498930549893055750762Eggerthella sp. YY7918, complete genomeputative thioesterase involved in non-ribosomal peptide biosynthesis3e-1789
NC_008463:4867504:486669248666924867507816Pseudomonas aeruginosa UCBPP-PA14, complete genomeputative thioesterase4e-1788.6
NC_020126:5558613:556927555692755570033759Myxococcus stipitatus DSM 14675, complete genomethioesterase4e-1788.2
NC_015711:5969061:597432259743225975044723Myxococcus fulvus HW-1 chromosome, complete genomethioesterase domain-containing protein2e-1686.3
NC_009255:2044291:206859620685962069432837Burkholderia vietnamiensis G4 chromosome 2, complete sequencethioesterase2e-1685.9
NC_017208:2432027:245442824544282455150723Bacillus thuringiensis serovar chinensis CT-43 chromosome, completethioesterase5e-1684.7
NC_014718:232832:241413241413242126714Burkholderia rhizoxinica HKI 454 chromosome, complete genomeThioesterase1e-1584
NC_008095:4061899:406716140671614067973813Myxococcus xanthus DK 1622, complete genomethioesterase domain protein1e-1583.6
NC_017093:5225864:524080452408045241574771Actinoplanes missouriensis 431, complete genomeputative thioesterase1e-1583.2
NC_014391:1910273:192691419269141927711798Micromonospora aurantiaca ATCC 27029 chromosome, complete genomethioesterase3e-1582
NC_012811:1:288722887229672801Methylobacterium extorquens AM1 megaplasmid, complete sequenceputative thioesterase4e-1581.6
NC_014623:5885903:589343358934335894218786Stigmatella aurantiaca DW4/3-1 chromosome, complete genomethioesterase1e-1480.1
NC_015957:5225903:524182952418295242575747Streptomyces violaceusniger Tu 4113 chromosome, complete genomeThioesterase2e-1479.7
NC_007005:2191500:221691722169172217675759Pseudomonas syringae pv. syringae B728a, complete genomeThioesterase2e-1479.3
NC_021182:1346261:134819613481961348900705Clostridium pasteurianum BC1, complete genomeputative thioesterase involved in non-ribosomal peptide biosynthesis4e-1478.6
NC_016582:7737930:776578377657837766391609Streptomyces bingchenggensis BCW-1 chromosome, complete genomeputative thioesterase5e-1478.2
NC_007645:2049988:206634820663482067052705Hahella chejuensis KCTC 2396, complete genomepredicted thioesterase involved in non-ribosomal peptide biosynthesis6e-1477.8
NC_014318:9120651:912528491252849126045762Amycolatopsis mediterranei U32 chromosome, complete genomethioesterase involved in non-ribosomal peptide biosynthesis1e-1376.6
NC_017186:9120711:912534491253449126105762Amycolatopsis mediterranei S699 chromosome, complete genomenon-ribosomal peptide biosynthesis thioesterase1e-1376.6
NC_016642:3554000:356676135667613567498738Pseudovibrio sp. FO-BEG1 chromosome, complete genomeCadicidin biosynthesis thioesterase2e-1376.3
NC_016631:4113794:413927741392774140056780Granulicella mallensis MP5ACTX8 chromosome, complete genomeoleoyl-(acyl-carrier-protein) hydrolase2e-1376.3
NC_016792:13963:340273402734740714Bacillus cereus NC7401 plasmid pNCcld, complete sequencecereulide biosynthesis protein2e-1375.9
NC_011655:230631:248831248831249544714Bacillus cereus AH187 plasmid pAH187_270, complete sequencetype II thioesterase, CesT2e-1375.9
NC_008278:2772726:278589727858972786451555Frankia alni ACN14a, complete genomePutative thioesterase3e-1375.5
NC_015711:7191968:720699172069917207779789Myxococcus fulvus HW-1 chromosome, complete genomeputative thioesterase6e-1374.7
NC_014172:166485:197630197630198358729Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequencethioesterase7e-1374.3
NC_009617:286500:286746286746287459714Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeoleoyl-(acyl-carrier-protein) hydrolase9e-1373.9
NC_004350:1252500:128757312875731288292720Streptococcus mutans UA159, complete genomeputative thioesterase BacT8e-1373.9
NC_017030:3091313:312597631259763126755780Corallococcus coralloides DSM 2259 chromosome, complete genomethioesterase3e-1169.3
NC_016111:4588021:459100945910094591815807Streptomyces cattleya NRRL 8057, complete genomeType II thioesterase3e-1168.9
NC_020181:473170:481700481700482269570Enterobacter aerogenes EA1509E, complete genomeiron aquisition yersiniabactin synthesis enzyme (YbtT,resembles thioesterases)7e-1167.8
NC_009792:859228:867758867758868327570Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein7e-1167.8
NC_008312:5861826:5887337588733758914014065Trichodesmium erythraeum IMS101, complete genomebeta-ketoacyl synthase7e-0960.8
NC_013855:196778:212201212201212965765Azospirillum sp. B510 plasmid pAB510a, complete sequenceCmaT protein3e-0755.8
NC_017030:3091313:312087531208753121705831Corallococcus coralloides DSM 2259 chromosome, complete genomeGramicidin S biosynthesis protein GrsT1e-0653.5
NC_008278:2772726:279348027934802794211732Frankia alni ACN14a, complete genomeputative thioesterase2e-0653.1