Pre_GI: BLASTP Hits

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Query: NC_017160:2362002:2372437 Yersinia pestis D182038 chromosome, complete genome

Start: 2372437, End: 2373072, Length: 636

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017154:2137500:2164830216483021666321803Yersinia pestis D106004 chromosome, complete genomeinner membrane ABC-transporter YbtQ1e-99362
NC_008253:1938975:1975379197537919771811803Escherichia coli 536, complete genomeinner membrane ABC-transporter YbtQ1e-99362
NC_005810:1794490:1822006182200618238081803Yersinia pestis biovar Microtus str. 91001, complete genomeinner membrane ABC-transporter YbtQ1e-99362
NC_006155:1916426:1943742194374219455441803Yersinia pseudotuberculosis IP 32953, complete genomeinner membrane ABC-transporter YbtQ1e-99362
NC_004088:2640440:2649734264973426515361803Yersinia pestis KIM, complete genomepermease and ATP-binding protein of yersiniabactin-iron ABC transporter1e-99362
NC_010634:1916000:1943726194372619455281803Yersinia pseudotuberculosis PB1/+, complete genomeABC transporter related1e-99362
NC_003143:2137945:2165262216526221670641803Yersinia pestis CO92, complete genomeinner membrane ABC-transporter YbtQ1e-99362
NC_008150:1420825:1448341144834114501431803Yersinia pestis Antiqua, complete genomeinner membrane ABC-transporter YbtQ1e-99362
NC_009381:1362471:1369135136913513709371803Yersinia pestis Pestoides F chromosome, complete genomeinner membrane ABC-transporter YbtQ1e-99362
NC_008563:2094855:2094855209485520966841830Escherichia coli APEC O1, complete genomeputative ABC transporter protein2e-99361
NC_011742:2002526:2002526200252620043551830Escherichia coli S88 chromosome, complete genomepermease and ATP-binding protein of yersiniabactin-iron ABC transporter YbtQ2e-99361
CU928145:2237099:2237099223709922389281830Escherichia coli 55989 chromosome, complete genomepermease and ATP-binding protein of yersiniabactin-iron ABC transporter YbtQ2e-99361
NC_011748:2237099:2237099223709922389281830Escherichia coli 55989, complete genomepermease and ATP-binding protein of yersiniabactin-iron ABC transporter YbtQ2e-99361
CP002797:2025330:2025330202533020271321803Escherichia coli NA114, complete genomeInner membrane ABC-transporter2e-99361
NC_010159:2164500:2191973219197321937751803Yersinia pestis Angola, complete genomeyersiniabactin ABC transporter, ATP-binding protein2e-99361
NC_013361:2757168:2757168275716827589701803Escherichia coli O26:H11 str. 11368 chromosome, complete genometransporter subunit2e-99361
NC_007946:2074098:2074098207409820759271830Escherichia coli UTI89, complete genomeputative ABC transporter protein3e-99360
NC_004431:2185750:2222220222222022240491830Escherichia coli CFT073, complete genomePutative ABC transporter protein3e-99360
NC_011750:1134721:1156964115696411587931830Escherichia coli IAI39 chromosome, complete genomeyersiniabactin-iron ABC transporter permease ATP-binding protein YbtQ3e-99360
NC_011751:2281653:2281653228165322834821830Escherichia coli UMN026 chromosome, complete genomeyersiniabactin-iron ABC transporter permease and ATP-binding protein YbtQ7e-99359
NC_020181:527592:5275925275925293941803Enterobacter aerogenes EA1509E, complete genomeInner membrane ABC-transporter YbtQ2e-98358
NC_011745:2168379:2168379216837921702081830Escherichia coli ED1a chromosome, complete genomeyersiniabactin-iron ABC transporter permease ATP-binding protein YbtQ2e-98358
NC_008800:2806827:2815212281521228170141803Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,inner membrane ABC-transporter YbtQ1e-97355
NC_017059:3688688:3706795370679537086421848Rhodospirillum photometricum DSM 122, complete genomeABC transporter transmembrane region1e-1272.8