Pre_GI: BLASTP Hits

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Query: NC_017160:2362002:2369996 Yersinia pestis D182038 chromosome, complete genome

Start: 2369996, End: 2371276, Length: 1281

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017154:2137500:2166625216662521679051281Yersinia pestis D106004 chromosome, complete genomeputative signal transducer2e-166585
NC_003143:2137945:2167057216705721683371281Yersinia pestis CO92, complete genomeputative signal transducer2e-166585
NC_010159:2164500:2193768219376821950481281Yersinia pestis Angola, complete genomeyersinabactin region putative transporter YbtX2e-166585
NC_006155:1916426:1945537194553719468171281Yersinia pseudotuberculosis IP 32953, complete genomeputative signal transducer or MFS Superfamily transporter2e-166585
NC_009381:1362471:1367862136786213692501389Yersinia pestis Pestoides F chromosome, complete genomesignal transducer5e-166584
NC_008150:1420825:1450028145002814514161389Yersinia pestis Antiqua, complete genomeputative signal transducer5e-166584
NC_011750:1134721:1158786115878611600661281Escherichia coli IAI39 chromosome, complete genomeyersiniabactin-iron transporter permease YbtX1e-165583
NC_004088:2640440:2648461264846126498641404Yersinia pestis KIM, complete genomehypothetical protein8e-166583
NC_011751:2281653:2280380228038022817831404Escherichia coli UMN026 chromosome, complete genomeyersiniabactin-iron transporter permease YbtX8e-166583
NC_005810:1794490:1823678182367818250811404Yersinia pestis biovar Microtus str. 91001, complete genomeputative signal transducer8e-166583
NC_010634:1916000:1945521194552119468011281Yersinia pseudotuberculosis PB1/+, complete genomemajor facilitator transporter6e-166583
CP002797:2025330:2024057202405720253371281Escherichia coli NA114, complete genomePutative cytoplasmic transmembrane protein1e-165582
NC_007946:2074098:2072825207282520742281404Escherichia coli UTI89, complete genomehypothetical protein4e-165581
NC_011742:2002526:2001253200125320026561404Escherichia coli S88 chromosome, complete genomeyersiniabactin-iron transporter permease YbtX4e-165581
NC_008253:1938975:1974106197410619754941389Escherichia coli 536, complete genomeputative cytoplasmic transmembrane protein4e-165581
NC_008563:2094855:2093582209358220949701389Escherichia coli APEC O1, complete genomehypothetical protein4e-165581
NC_004431:2185750:2220947222094722223501404Escherichia coli CFT073, complete genomePutative cytoplasmic transmembrane protein4e-165581
NC_020181:527592:5293875293875306671281Enterobacter aerogenes EA1509E, complete genomePutative signal transducer3e-165581
NC_011748:2237099:2235826223582622372291404Escherichia coli 55989, complete genomeyersiniabactin-iron transporter permease YbtX1e-164579
CU928145:2237099:2235826223582622372291404Escherichia coli 55989 chromosome, complete genomeputative permease of yersiniabactin-iron transporter YbtX1e-164579
NC_008800:2806827:2813939281393928152191281Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,putative signal transducer3e-163575
NC_011745:2168379:2167106216710621685091404Escherichia coli ED1a chromosome, complete genomeyersiniabactin-iron transporter permease YbtX2e-163575
NC_013361:2757168:2755895275589527571751281Escherichia coli O26:H11 str. 11368 chromosome, complete genomecytoplasmic transmembrane protein6e-163573
NC_012962:2587756:2611946261194626131931248Photorhabdus asymbiotica, complete genomeputative cytoplasmic transmembrane protein5e-1892.8
NC_008686:1439328:1460233146023314614201188Paracoccus denitrificans PD1222 chromosome 1, complete sequencemajor facilitator superfamily MFS_13e-1170.1