Pre_GI: BLASTP Hits

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Query: NC_017154:3997810:4019326 Yersinia pestis D106004 chromosome, complete genome

Start: 4019326, End: 4019934, Length: 609

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009708:483253:504775504775505419645Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein2e-117421
NC_003143:4105754:412724041272404127878639Yersinia pestis CO92, complete genomehypothetical protein2e-117420
NC_017168:1729922:175143817514381752046609Yersinia pestis A1122 chromosome, complete genomehypothetical protein3e-117420
NC_014029:4057696:407921240792124079820609Yersinia pestis Z176003 chromosome, complete genomehypothetical protein3e-117420
NC_009381:321577:343094343094343702609Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein3e-117420
NC_007606:3842708:385915438591543859909756Shigella dysenteriae Sd197, complete genomehypothetical protein3e-64244
NC_013353:3853082:388902538890253889621597Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein6e-49193
AP010958:3853082:388902538890253889621597Escherichia coli O103:H2 str. 12009 DNA, complete genomehypothetical protein6e-49193
NC_011745:291422:297377297377298057681Escherichia coli ED1a chromosome, complete genomehypothetical protein3e-38157