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Query: NC_017154:3997810:4016101 Yersinia pestis D106004 chromosome, complete genome

Start: 4016101, End: 4016574, Length: 474

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:1729922:174821317482131748686474Yersinia pestis A1122 chromosome, complete genomeribonuclease2e-73274
NC_010465:522649:540921540921541394474Yersinia pseudotuberculosis YPIII, complete genomeguanine-specific ribonuclease N1 and T12e-73274
NC_008150:4140804:415908541590854159558474Yersinia pestis Antiqua, complete genomeputative ribonuclease2e-73274
NC_009381:321577:339869339869340342474Yersinia pestis Pestoides F chromosome, complete genomeribonuclease2e-73274
NC_009708:483253:501729501729502202474Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeribonuclease Ba2e-73274
NC_014029:4057696:407598740759874076460474Yersinia pestis Z176003 chromosome, complete genomeribonuclease2e-73274
NC_003143:4105754:412406041240604124518459Yersinia pestis CO92, complete genomeputative ribonuclease5e-71266
NC_012214:2019000:203920120392012039671471Erwinia pyrifoliae Ep1/96, complete genomeRibonuclease3e-39160
UCMB5137:2128500:213982821398282140103276Bacillus atrophaeus UCMB-5137ribonuclease precursor (Barnase)1e-28125
NC_017505:670919:6756086756086775931986Neisseria meningitidis alpha710 chromosome, complete genomeMafB-like protein3e-1374.3