Pre_GI: BLASTP Hits

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Query: NC_017154:3997810:4008727 Yersinia pestis D106004 chromosome, complete genome

Start: 4008727, End: 4009539, Length: 813

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004088:179775:185744185744186619876Yersinia pestis KIM, complete genometranscriptional regulator4e-136483
NC_010465:522649:533546533546534358813Yersinia pseudotuberculosis YPIII, complete genometranscriptional regulator, LysR family7e-136483
NC_017160:3986844:399287639928763993688813Yersinia pestis D182038 chromosome, complete genomelysR-family transcriptional regulatory protein7e-136483
NC_008150:4140804:415171141517114152577867Yersinia pestis Antiqua, complete genomeputative lysR-family transcriptional regulatory protein4e-136483
NC_003143:4105754:411667141166714117537867Yersinia pestis CO92, complete genomeputative lysR-family transcriptional regulatory protein4e-136483
NC_010159:1208699:121501812150181215884867Yersinia pestis Angola, complete genometranscriptional regulator, LysR family4e-136483
NC_008149:3966586:397256439725643973430867Yersinia pestis Nepal516, complete genomelysR-family transcriptional regulatory protein4e-136483
NC_009381:321577:332495332495333361867Yersinia pestis Pestoides F chromosome, complete genomeLysR family transcriptional regulator4e-136483
NC_017168:1729922:174083917408391741705867Yersinia pestis A1122 chromosome, complete genomeLysR family transcriptional regulator4e-136483
NC_017265:4171500:417670041767004177566867Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative lysR-family transcriptional regulatory protein4e-136483
NC_005810:4381182:438748643874864388361876Yersinia pestis biovar Microtus str. 91001, complete genomeLysR family transcriptional regulator4e-136483
NC_010634:4150763:415713141571314157943813Yersinia pseudotuberculosis PB1/+, complete genomeLysR family transcriptional regulator3e-135481
NC_006155:4210606:421692042169204217786867Yersinia pseudotuberculosis IP 32953, complete genomeputative lysR-family transcriptional regulatory protein5e-135480
NC_014029:4057696:406861340686134069383771Yersinia pestis Z176003 chromosome, complete genomelysR-family transcriptional regulatory protein8e-127452
NC_009708:483253:494332494332495219888Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeLysR family transcriptional regulator8e-109393
NC_015224:4028150:403274040327404033606867Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative lysR-family transcriptional regulator9e-76283
NC_014228:2270000:2290027229002722910401014Xenorhabdus nematophila ATCC 19061, complete genomehypothetical protein5e-0961.6
NC_006155:1074298:108492010849201085831912Yersinia pseudotuberculosis IP 32953, complete genomeputative LysR-family transcriptional regulatory protein1e-0653.5
NC_005810:754340:765018765018765929912Yersinia pestis biovar Microtus str. 91001, complete genomeLysR family transcriptional regulator1e-0653.5
NC_004088:1075454:108528210852821086193912Yersinia pestis KIM, complete genomeLysR-type transcriptional regulatory protein1e-0653.5
NC_008150:3015000:302406730240673024978912Yersinia pestis Antiqua, complete genomeputative LysR-family transcriptional regulatory protein1e-0653.5
NC_003143:3583468:359238935923893593300912Yersinia pestis CO92, complete genomeputative LysR-family transcriptional regulatory protein1e-0653.5
NC_008149:1002453:101228110122811013192912Yersinia pestis Nepal516, complete genomeLysR-family transcriptional regulatory protein1e-0653.5
NC_009381:3228500:323665332366533237564912Yersinia pestis Pestoides F chromosome, complete genomeLysR family transcriptional regulator1e-0653.5
NC_009708:3542336:355125635512563552167912Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeLysR family transcriptional regulator1e-0653.5
NC_017168:2158839:216866721686672169578912Yersinia pestis A1122 chromosome, complete genomeputative LysR family transcriptional regulator1e-0653.5
NC_017265:3375463:338472933847293385640912Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative LysR-family transcriptional regulatory protein1e-0653.5
NC_014618:4657719:468652846865284687457930Enterobacter cloacae SCF1 chromosome, complete genomeLysR family transcriptional regulator2e-0653.5