Pre_GI: BLASTP Hits

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Query: NC_017154:394401:403101 Yersinia pestis D106004 chromosome, complete genome

Start: 403101, End: 404426, Length: 1326

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:4065625:4075194407519440765191326Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,modification methylase0838
NC_010159:1288000:1295481129548112968061326Yersinia pestis Angola, complete genomemodification methylase0838
NC_003143:398748:4074494074494087741326Yersinia pestis CO92, complete genomemodification methylase0838
NC_008149:318860:3266573266573279821326Yersinia pestis Nepal516, complete genomemodification methylase0838
NC_008150:4373722:4383291438329143846161326Yersinia pestis Antiqua, complete genomemodification methylase0838
NC_004088:4202247:4211816421181642131411326Yersinia pestis KIM, complete genomemethyltransferase0838
NC_014029:452248:4609494609494622741326Yersinia pestis Z176003 chromosome, complete genomemodification methylase0838
NC_017160:396600:4053014053014066261326Yersinia pestis D182038 chromosome, complete genomemodification methylase0838
NC_017168:687471:6970406970406983651326Yersinia pestis A1122 chromosome, complete genomemodification methylase0838
NC_005810:4306716:4316108431610843174391332Yersinia pestis biovar Microtus str. 91001, complete genomemodification methylase0833
NC_009381:3680638:3690229369022936913081080Yersinia pestis Pestoides F chromosome, complete genomemodification methylase0666
NC_014376:317312:3242053242053254671263Clostridium saccharolyticum WM1 chromosome, complete genomemodification methylase6e-49195
NC_013552:1187299:1199281119928112005371257Dehalococcoides sp. VS, complete genomeadenine-specific DNA methylase8e-42171
NC_020387:1257163:1268633126863312698891257Dehalococcoides mccartyi BTF08, complete genomeDNA methyltransferase8e-42171
NC_013890:1142500:1153526115352611547821257Dehalococcoides sp. GT chromosome, complete genomeSite-specific DNA-methyltransferase (cytosine-N(4)-specific)7e-42171
NC_013037:1072266:1087955108795510891931239Dyadobacter fermentans DSM 18053, complete genomeadenine-specific DNA methylase5e-37155
NC_012030:345837:3556403556403570011362Halorubrum lacusprofundi ATCC 49239 plasmid pHLAC01, completeadenine-specific DNA methylase6e-35149
NC_015381:3091500:3108388310838831098031416Burkholderia gladioli BSR3 chromosome 1, complete sequencehypothetical protein5e-1789.4
NC_007614:2517226:2526538252653825279411404Nitrosospira multiformis ATCC 25196 chromosome 1, completehypothetical protein1e-1584.7
NC_009921:1736000:1751686175168617530771392Frankia sp. EAN1pec, complete genomeputative RNA methylase5e-1479.3
NC_010943:1884695:1894288189428818957121425Stenotrophomonas maltophilia K279a, complete genomeputative modification methylase1e-1275.1
NC_011146:382719:4013104013104025631254Geobacter bemidjiensis Bem, complete genomehypothetical protein9e-1065.1
NC_009952:1984955:2001559200155920026201062Dinoroseobacter shibae DFL 12, complete genomeputative modification methylase1e-0758.2
NC_000909:1408276:1416977141697714185691593Methanocaldococcus jannaschii DSM 2661, complete genomemodification methylase, type II R/M system2e-0757.8
NC_008260:2340824:2364789236478923669032115Alcanivorax borkumensis SK2, complete genomehypothetical protein8e-0755.5
NC_009767:5230790:5238059523805952395101452Roseiflexus castenholzii DSM 13941, complete genomeputative RNA methylase4e-0653.1