Pre_GI: BLASTP Hits

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Query: NC_017154:3576256:3597944 Yersinia pestis D106004 chromosome, complete genome

Start: 3597944, End: 3599287, Length: 1344

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:3560153:3581841358184135831841344Yersinia pestis D182038 chromosome, complete genomeNa(+)-translocating NADH-quinone reductase subunit A0883
NC_009381:3228500:3249420324942032508021383Yersinia pestis Pestoides F chromosome, complete genomeNa(+)-translocating NADH-quinone reductase subunit A0883
NC_008150:3015000:3036834303683430382161383Yersinia pestis Antiqua, complete genomeNADH-ubiquinone oxidoreductase subunit A0883
NC_010159:3502350:3524066352406635254091344Yersinia pestis Angola, complete genomeNADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit0882
NC_010465:3597000:3617881361788136192421362Yersinia pseudotuberculosis YPIII, complete genomeNADH:ubiquinone oxidoreductase, subunit A0881
NC_009708:3542336:3564024356402435653671344Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeNa(+)-translocating NADH-quinone reductase subunit A0880
NC_014029:3633955:3655643365564336568721230Yersinia pestis Z176003 chromosome, complete genomeNa translocating NADH:ubiquinone oxidoreductase subunit A0807
NC_015276:2852010:2860540286054028618771338Marinomonas mediterranea MMB-1 chromosome, complete genomeNa(+)-translocating NADH-quinone reductase subunit A4e-148525
NC_004459:1794540:1816194181619418174801287Vibrio vulnificus CMCP6 chromosome I, complete sequenceNa(+)-translocating NADH-quinone reductase subunit A4e-147521
NC_010506:4404377:4411607441160744130251419Shewanella woodyi ATCC 51908, complete genomeNADH:ubiquinone oxidoreductase, subunit A1e-146520
NC_012881:334250:3494983494983508381341Desulfovibrio salexigens DSM 2638, complete genomeNADH:ubiquinone oxidoreductase, subunit A4e-128458
NC_013939:1927424:1939739193973919410581320Deferribacter desulfuricans SSM1, complete genomeNa(+)-translocating NADH-quinone reductase subunit A2e-68260
NC_015571:1265121:1281851128185112832061356Porphyromonas gingivalis TDC60, complete genomeNa(+)-translocating NADH-quinone reductase, subunit A2e-62240