Pre_GI: BLASTP Hits

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Query: NC_017154:3094000:3115974 Yersinia pestis D106004 chromosome, complete genome

Start: 3115974, End: 3121952, Length: 5979

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004088:1265730:1284186128418612902006015Yersinia pestis KIM, complete genomehypothetical protein03949
NC_008149:1195614:1214070121407012200485979Yersinia pestis Nepal516, complete genomemembrane protein03948
NC_013416:939668:9569369569369627075772Aggregatibacter actinomycetemcomitans D11S-1, complete genomealpha-2-macroglobulin domain protein01199
NC_016050:771752:7915197915197971975679Rickettsia japonica YH, complete genomelarge extracellular alpha-helical protein0946
NC_015866:767790:7899487899487956265679Rickettsia heilongjiangensis 054 chromosome, complete genomelarge extracellular alpha-helical protein0944
NC_017066:683000:6994716994717051525682Rickettsia typhi str. TH1527 chromosome, complete genomelarge extracellular alpha-helical protein0912
NC_017062:685321:7000397000397057205682Rickettsia typhi str. B9991CWPP chromosome, complete genomelarge extracellular alpha-helical protein0912
NC_006142:683000:6994596994597051405682Rickettsia typhi str. Wilmington, complete genomehypothetical protein0912
NC_017049:675261:6905786905786962445667Rickettsia prowazekii str. Chernikova chromosome, complete genomelarge extracellular alpha-helical protein0896
NC_017051:674000:6905906905906962565667Rickettsia prowazekii str. Dachau chromosome, complete genomelarge extracellular alpha-helical protein0896
NC_017056:678450:6924246924246980905667Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomelarge extracellular alpha-helical protein0895
NC_017050:676000:6924476924476981135667Rickettsia prowazekii str. Katsinyian chromosome, complete genomelarge extracellular alpha-helical protein0895
NC_017057:679113:6927106927106983765667Rickettsia prowazekii str. RpGvF24 chromosome, complete genomelarge extracellular alpha-helical protein0895
NC_017048:1018000:1035039103503910402855247Rickettsia prowazekii str. GvV257 chromosome, complete genomelarge extracellular alpha-helical protein0861
NC_000963:676000:6924536924536956863234Rickettsia prowazekii str. Madrid E, complete genomehypothetical protein3e-125451
NC_000963:676000:6956896956896981182430Rickettsia prowazekii str. Madrid E, complete genomehypothetical protein6e-120433
NC_020054:765511:7816337816337872245592Fibrella aestuarina BUZ 2 drat genomealpha-2-macroglobulin domain protein3e-92342
NC_008255:1344674:1368153136815313735765424Cytophaga hutchinsonii ATCC 33406, complete genomehypothetical protein2e-85318
NC_009615:1067603:1077187107718710827245538Parabacteroides distasonis ATCC 8503 chromosome, complete genomeouter membrane protein3e-61238
NC_015496:1590674:1594781159478116003575577Krokinobacter diaphorus 4H-3-7-5 chromosome, complete genomealpha-2-macroglobulin domain protein4e-53211
NC_015638:1029721:1053034105303410586165583Lacinutrix sp. 5H-3-7-4 chromosome, complete genomealpha-2-macroglobulin domain-containing protein7e-50200
NC_019940:3480690:3480690348069034862005511Thioflavicoccus mobilis 8321 chromosome, complete genomelarge extracellular alpha-helical protein1e-48196
NC_009348:2836969:2855043285504328598604818Aeromonas salmonicida subsp. salmonicida A449, complete genomelarge extracellular protein6e-48194
NC_010644:691374:6931736931736987915619Elusimicrobium minutum Pei191, complete genomealpha-2-macroglobulin domain-containing protein1e-44183
NC_004663:163152:1699831699831753585376Bacteroides thetaiotaomicron VPI-5482, complete genomehypothetical protein4e-44181
NC_017243:1041917:1059449105944910651755727Brachyspira intermedia PWS/A chromosome, complete genomealpha-2-macroglobulin domain-containing protein2e-38162
NC_012225:1071159:1076667107666710823935727Brachyspira hyodysenteriae WA1, complete genomeputative alpha-2-macroglobulin domain protein8e-37157
NC_010995:4338860:4338860433886043445325673Cellvibrio japonicus Ueda107, complete genomeAlpha-2-macroglobulin family N-terminal region family3e-36155
NC_014150:2501299:2506185250618525119355751Brachyspira murdochii DSM 12563 chromosome, complete genomealpha-2-macroglobulin domain protein1e-32143
NC_011206:1873297:1886164188616418916505487Acidithiobacillus ferrooxidans ATCC 53993, complete genomealpha-2-macroglobulin domain protein2e-28129
NC_009767:3335021:3357153335715333637406588Roseiflexus castenholzii DSM 13941, complete genomealpha-2-macroglobulin domain protein7e-25117
NC_015500:2950660:2964878296487829709046027Treponema brennaborense DSM 12168 chromosome, complete genomealpha-2-macroglobulin domain protein 29e-0654.3