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Query: NC_017154:2901300:2901300 Yersinia pestis D106004 chromosome, complete genome

Start: 2901300, End: 2902289, Length: 990

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:2560000:2561260256126025622971038Yersinia pestis A1122 chromosome, complete genomecytoskeletal protein RodZ2e-165581
NC_008150:2599661:2599661259966126006981038Yersinia pestis Antiqua, complete genomeputative DNA-binding protein2e-165581
NC_010159:409500:4347854347854358221038Yersinia pestis Angola, complete genomehypothetical protein2e-165581
NC_010634:3269010:3275201327520132762891089Yersinia pseudotuberculosis PB1/+, complete genomeXRE family transcriptional regulator5e-153540
NC_011601:2854178:2877260287726028782671008Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomecytoskeletal protein RodZ6e-88324
NC_016893:181951:190112190112190609498Wigglesworthia glossinidia endosymbiont of Glossina morsitansputative DNA-binding protein2e-1686.3
NC_004344:622318:641232641232641708477Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,hypothetical protein5e-1582
NC_015222:1127675:1136550113655011377761227Nitrosomonas sp. AL212 chromosome, complete genometranscriptional regulator, XRE family2e-0757