Pre_GI: BLASTP Hits

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Query: NC_017154:2100587:2101444 Yersinia pestis D106004 chromosome, complete genome

Start: 2101444, End: 2102574, Length: 1131

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013131:4422000:4423881442388144251131233Catenulispora acidiphila DSM 44928, complete genomehypothetical protein4e-50199
NC_013716:1178383:1181023118102311821501128Citrobacter rodentium ICC168, complete genomehypothetical protein4e-159561
NC_012704:2347969:2371349237134923726891341Corynebacterium kroppenstedtii DSM 44385, complete genomeputative lipoprotein involved in iron transport4e-40165
NC_013592:1465015:1467741146774114688621122Dickeya dadantii Ech586, complete genomePeptidase M75, Imelysin4e-172604
NC_015663:3466471:3469282346928234704091128Enterobacter aerogenes KCTC 2190 chromosome, complete genomeinactive ferrous ion transporter periplasmic protein EfeO1e-159562
NC_010468:2809125:2826361282636128274881128Escherichia coli ATCC 8739, complete genomehypothetical protein1e-161569
NC_013364:1257801:1258689125868912598161128Escherichia coli O111:H- str. 11128, complete genomehypothetical protein2e-162571
NC_011601:1114104:1114992111499211161191128Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomehypothetical protein4e-163574
NC_013361:1284579:1285467128546712865941128Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein2e-162571
NC_007777:4016000:4035140403514040372482109Frankia sp. CcI3, complete genomeiron permease FTR15e-22105
NC_015656:2900730:2900730290073029028712142Frankia symbiont of Datisca glomerata chromosome, complete genomeiron permease FTR14e-23109
NC_013192:1886337:190410119041011904982882Leptotrichia buccalis DSM 1135, complete genomeperiplasmic iron transport lipoprotein, putative5e-47188
NC_012660:3179980:3182145318214531833471203Pseudomonas fluorescens SBW25 chromosome, complete genomehypothetical protein2e-75282
NC_012660:3179980:317998031799803180798819Pseudomonas fluorescens SBW25 chromosome, complete genomeputative lipoprotein2e-79296
NC_013715:1606396:1607903160790316091291227Rothia mucilaginosa DY-18, complete genomepredicted periplasmic lipoprotein involved in iron transport5e-44178
NC_014168:471000:4930974930974942511155Segniliparus rotundus DSM 44985 chromosome, complete genomepeptidase M752e-49196
NC_020211:3151458:3167111316711131682471137Serratia marcescens WW4, complete genomeinactive ferrous ion transporter EfeUOB6e-180630
NC_017328:1075535:1075535107553510766621128Shigella flexneri 2002017 chromosome, complete genomeprotein ycdO precursor1e-161569
NC_004337:1065609:1065609106560910667361128Shigella flexneri 2a str. 301, complete genomehypothetical protein1e-161569
NC_017168:3535786:3557981355798135591111131Yersinia pestis A1122 chromosome, complete genomeinactive ferrous ion transporter periplasmic protein EfeO0770
NC_010159:2128157:2129044212904421301741131Yersinia pestis Angola, complete genomehypothetical protein0770
NC_008150:1384102:1384980138498013861101131Yersinia pestis Antiqua, complete genomehypothetical protein0770
NC_005810:1663672:1686269168626916874231155Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0771
NC_003143:2101902:2101902210190221030321131Yersinia pestis CO92, complete genomehypothetical protein0770
NC_017160:2414000:2436038243603824371681131Yersinia pestis D182038 chromosome, complete genomehypothetical protein0770
NC_004088:2691565:2713796271379627149501155Yersinia pestis KIM, complete genomehypothetical protein0771
NC_009381:1414985:1433153143315314342831131Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0770
NC_014029:2388500:2407032240703224081621131Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0770
NC_010465:2582080:2599370259937026005001131Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein0763