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Query: NC_017154:1644404:1665423 Yersinia pestis D106004 chromosome, complete genome

Start: 1665423, End: 1665755, Length: 333

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:1628500:164591816459181646250333Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-60229
NC_014029:1702338:172335617233561723688333Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-60229
NC_010465:2820500:285867828586782859010333Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein5e-60229
NC_010159:3120642:313601431360143136346333Yersinia pestis Angola, complete genomehypothetical protein5e-60229
NC_010634:1755548:177348617734861773818333Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein5e-60229
NC_003143:1630000:165368416536841654172489Yersinia pestis CO92, complete genomehypothetical protein1e-59228
NC_008149:2802392:282951828295182830006489Yersinia pestis Nepal516, complete genomehypothetical protein1e-59228
NC_004088:2966331:299345429934542993942489Yersinia pestis KIM, complete genomehypothetical protein1e-59228
NC_009381:1682000:171079317107931711281489Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-59228
NC_017168:3977767:400489940048994005387489Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-59228
NC_006155:1756000:177313017731301773570441Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein8e-60228
NC_009708:2788855:284713428471342847574441Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein8e-60228
NC_017265:2586729:261385526138552614295441Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein8e-60228
NC_008150:844727:865616865616866077462Yersinia pestis Antiqua, complete genomehypothetical protein6e-60228
NC_005810:1467772:148259514825951483083489Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-59228