Pre_GI: BLASTP Hits

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Query: NC_017154:1644404:1646519 Yersinia pestis D106004 chromosome, complete genome

Start: 1646519, End: 1646983, Length: 465

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014029:1702338:170445317044531704917465Yersinia pestis Z176003 chromosome, complete genomemethylglyoxal synthase4e-87319
NC_008150:844727:846842846842847306465Yersinia pestis Antiqua, complete genomemethylglyoxal synthase4e-87319
NC_008149:2802392:284828928482892848753465Yersinia pestis Nepal516, complete genomemethylglyoxal synthase4e-87319
NC_003143:1630000:163493716349371635401465Yersinia pestis CO92, complete genomemethylglyoxal synthase4e-87319
NC_013421:3093995:311224031122403112698459Pectobacterium wasabiae WPP163, complete genomemethylglyoxal synthase3e-65246
NC_006511:1808815:182934118293411829799459Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCmethylglyoxal synthase1e-62238
NC_011149:1035990:103808010380801038538459Salmonella enterica subsp. enterica serovar Agona str. SL483,methylglyoxal synthase1e-62238
NC_010102:2020762:203905520390552039513459Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein1e-62238
NC_010067:1829041:185540118554011855859459Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein1e-62238
NC_004631:1881214:190279519027951903253459Salmonella enterica subsp. enterica serovar Typhi Ty2, completemethylglyoxal synthase1e-62238
NC_011147:1802535:182452418245241824982459Salmonella enterica subsp. enterica serovar Paratyphi A strmethylglyoxal synthase1e-62238
NC_012125:2687980:270628427062842706742459Salmonella enterica subsp. enterica serovar Paratyphi C strainmethylglyoxal synthase1e-62238
NC_016832:1880174:189964518996451900103459Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Methylglyoxal synthase1e-62238
NC_012880:3125261:314536831453683145826459Dickeya dadantii Ech703, complete genomemethylglyoxal synthase5e-62236
NC_014618:2989000:300650930065093006967459Enterobacter cloacae SCF1 chromosome, complete genomemethylglyoxal synthase2e-61234
NC_016831:1950650:196895319689531969396444Salmonella enterica subsp. enterica serovar Gallinarum/pullorummethylglyoxal synthase7e-60229
NC_010519:275976:278166278166278624459Haemophilus somnus 2336 chromosome, complete genomemethylglyoxal synthase1e-54211
NC_008578:1827605:182966418296641830167504Acidothermus cellulolyticus 11B, complete genomemethylglyoxal synthase3e-42170
NC_014960:3009500:301670130167013017156456Anaerolinea thermophila UNI-1, complete genomemethylglyoxal synthase9e-41165
NC_007760:1415663:143657914365791437055477Anaeromyxobacter dehalogenans 2CP-C, complete genomemethylglyoxal synthase2e-39161
NC_004663:1365429:138525613852561385792537Bacteroides thetaiotaomicron VPI-5482, complete genomemethylglyoxal synthase2e-30130
NC_006347:4378684:439488743948874395405519Bacteroides fragilis YCH46, complete genomemethylglyoxal synthase2e-29127
NC_007530:1459412:146648514664851466880396Bacillus anthracis str. 'Ames Ancestor', complete genomemethylglyoxal synthase2e-29127
NC_005945:1459357:146643914664391466834396Bacillus anthracis str. Sterne, complete genomemethylglyoxal synthase2e-29127
NC_006569:370846:370463370463370852390Silicibacter pomeroyi DSS-3 megaplasmid, complete sequencemethylglyoxal synthase3e-27120
NC_014328:794000:809537809537809908372Clostridium ljungdahlii ATCC 49587 chromosome, complete genomemethylglyoxal synthase6e-27119
NC_005835:1345790:136439913643991364785387Thermus thermophilus HB27, complete genomemethylglyoxal synthase7e-27119
NC_017078:179848:179848179848180264417Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC1,putative methylglyoxal synthase2e-26117
NC_009633:2350892:236544323654432365847405Alkaliphilus metalliredigens QYMF chromosome, complete genomemethylglyoxal synthase7e-26115
NC_017179:1197763:121967712196771220090414Clostridium difficile BI1, complete genomemethylglyoxal synthase4e-25113
NC_013315:1187986:120990012099001210313414Clostridium difficile CD196 chromosome, complete genomemethylglyoxal synthase4e-25113
NC_009089:1329826:135174013517401352153414Clostridium difficile 630, complete genomemethylglyoxal synthase4e-25113
NC_015136:1141925:116979411697941170183390Burkholderia sp. CCGE1001 chromosome 1, complete sequencemethylglyoxal synthase2e-24110
NC_007516:2277910:232647723264772327370894Synechococcus sp. CC9605, complete genomecyclic nucleotide-binding domain (cNMP-BD) protein9e-22102
NC_014221:266638:274456274456274881426Truepera radiovictrix DSM 17093 chromosome, complete genomemethylglyoxal synthase1e-21102
NC_011060:1288862:131154813115481312534987Pelodictyon phaeoclathratiforme BU-1, complete genomeMethylglyoxal synthase-like protein9e-0959.3
NC_010002:5691968:570910357091035709975873Delftia acidovorans SPH-1, complete genomehypothetical protein4e-0753.9