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Query: NC_017066:33268:51017 Rickettsia typhi str. TH1527 chromosome, complete genome

Start: 51017, End: 51268, Length: 252

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017062:33268:509845098451235252Rickettsia typhi str. B9991CWPP chromosome, complete genomehypothetical protein3e-30130
NC_006142:33268:510175101751268252Rickettsia typhi str. Wilmington, complete genomerickettsial conserved hypothetical protein3e-30130
NC_016929:109500:109519109519109767249Rickettsia canadensis str. CA410 chromosome, complete genomealanine racemase3e-2097.1
NC_009879:107890:108694108694108942249Rickettsia canadensis str. McKiel, complete genomealanine racemase3e-2097.1
NC_007940:1435701:143960314396031439851249Rickettsia bellii RML369-C, complete genomehypothetical protein4e-1786.7
NC_009883:140890:154755154755155003249Rickettsia bellii OSU 85-389, complete genomehypothetical protein4e-1786.7