Pre_GI: BLASTP Hits

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Query: NC_017066:312000:326598 Rickettsia typhi str. TH1527 chromosome, complete genome

Start: 326598, End: 326918, Length: 321

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006142:312000:326584326584326904321Rickettsia typhi str. Wilmington, complete genomehypothetical protein1e-38157
NC_017043:1055569:107699010769901077310321Rickettsia montanensis str. OSU 85-930 chromosome, complete genomeputative monovalent cation/H+ antiporter subunit G5e-33139
NC_016915:346000:360232360232360552321Rickettsia rickettsii str. Hlp#2 chromosome, complete genomeputative monovalent cation/H+ antiporter subunit G6e-32135
NC_013849:627811:627811627811628140330Ferroglobus placidus DSM 10642 chromosome, complete genomemonovalent cation/proton antiporter, MnhG/PhaG subunit2e-0857.8
NC_009831:4447919:446512644651264465467342Shewanella sediminis HAW-EB3, complete genomeMultisubunit Na+/H+ antiporter MnhG subunit-like protein5e-0856.6
NC_012982:1282856:128919812891981289602405Hirschia baltica ATCC 49814, complete genomemonovalent cation/proton antiporter, MnhG/PhaG subunit2e-0651.2
NC_013166:784339:790056790056790430375Kangiella koreensis DSM 16069, complete genomemonovalent cation/proton antiporter, MnhG/PhaG subunit4e-0650.1
NC_018697:825058:831016831016831348333Cycloclasticus sp. P1 chromosome, complete genomeMultisubunit Na+/H+ antiporter MnhG subunit-like protein7e-0649.3