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Query: NC_017066:312000:324435 Rickettsia typhi str. TH1527 chromosome, complete genome

Start: 324435, End: 324941, Length: 507

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006142:312000:324421324421324927507Rickettsia typhi str. Wilmington, complete genomehypothetical protein8e-91332
NC_017043:1055569:107469310746931075247555Rickettsia montanensis str. OSU 85-930 chromosome, complete genomeouter membrane protein3e-83306
NC_016915:346000:357935357935358489555Rickettsia rickettsii str. Hlp#2 chromosome, complete genomeOuter membrane protein6e-83305
NC_009883:1197500:121709712170971217651555Rickettsia bellii OSU 85-389, complete genomeOuter membrane protein4e-65246
NC_007940:322948:330155330155330709555Rickettsia bellii RML369-C, complete genomeOuter membrane protein4e-65246