Query: NC_017063:775337 Helicobacter pylori ELS37 chromosome, complete genome
Start: 775337, End: 798127, Length: 22791
Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria
General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_010698:819912 | 819912 | 844300 | 24389 | Helicobacter pylori Shi470, complete genome | 0 | 878 | BLASTN svg | BLASTP svg |
NC_009850:972692* | 972692 | 998089 | 25398 | Arcobacter butzleri RM4018, complete genome | 5e-11 | 77.8 | BLASTN svg | BLASTP svg |
NC_013730:1572889* | 1572889 | 1597611 | 24723 | Spirosoma linguale DSM 74, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_005061:647567* | 647567 | 672145 | 24579 | Candidatus Blochmannia floridanus, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_012039:412837* | 412837 | 456485 | 43649 | Campylobacter lari RM2100, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_005945:5053000* | 5053000 | 5074651 | 21652 | Bacillus anthracis str. Sterne, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_005957:5037499* | 5037499 | 5078114 | 40616 | Bacillus thuringiensis serovar konkukian str. 97-27, complete | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_007530:5033095* | 5033095 | 5072211 | 39117 | Bacillus anthracis str. 'Ames Ancestor', complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_008600:5046000* | 5046000 | 5100703 | 54704 | Bacillus thuringiensis str. Al Hakam, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_012472:5094009* | 5094009 | 5113124 | 19116 | Bacillus cereus 03BB102, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_014335:5005267* | 5005267 | 5025620 | 20354 | Bacillus cereus biovar anthracis str. CI chromosome, complete | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_003997:5032969* | 5032969 | 5072099 | 39131 | Bacillus anthracis str. Ames, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |