Query: NC_017026:3754000 Mycobacterium tuberculosis RGTB327 chromosome, complete genome
Start: 3754000, End: 3776830, Length: 22831
Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
---|
NC_000962:3781501 | 3781501 | 3807573 | 26073 | Mycobacterium tuberculosis H37Rv, complete genome | 0 | 34240 | BLASTN svg | BLASTP svg |
NC_009525:3794000 | 3794000 | 3816251 | 22252 | Mycobacterium tuberculosis H37Ra, complete genome | 0 | 33980 | BLASTN svg | BLASTP svg |
NC_009565:3793976 | 3793976 | 3818690 | 24715 | Mycobacterium tuberculosis F11, complete genome | 0 | 20400 | BLASTN svg | BLASTP svg |
NC_002755:3773734 | 3773734 | 3798448 | 24715 | Mycobacterium tuberculosis CDC1551, complete genome | 0 | 20370 | BLASTN svg | BLASTP svg |
NC_002945:3735141 | 3735141 | 3760774 | 25634 | Mycobacterium bovis AF2122/97, complete genome | 0 | 20320 | BLASTN svg | BLASTP svg |
NC_008769:3769065 | 3769065 | 3794701 | 25637 | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome | 0 | 20310 | BLASTN svg | BLASTP svg |
NC_012207:3766978 | 3766978 | 3792614 | 25637 | Mycobacterium bovis BCG str. Tokyo 172, complete genome | 0 | 20310 | BLASTN svg | BLASTP svg |
NC_019950:3818000 | 3818000 | 3840147 | 22148 | Mycobacterium canettii CIPT 140060008 complete genome | 0 | 19900 | BLASTN svg | BLASTP svg |
NC_015848:3851230 | 3851230 | 3876717 | 25488 | Mycobacterium canettii CIPT 140010059, complete genome | 0 | 19770 | BLASTN svg | BLASTP svg |
NC_000962:3116818 | 3116818 | 3136333 | 19516 | Mycobacterium tuberculosis H37Rv, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_002755:3110929 | 3110929 | 3129757 | 18829 | Mycobacterium tuberculosis CDC1551, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_002945:3073370 | 3073370 | 3094599 | 21230 | Mycobacterium bovis AF2122/97, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_008769:3070266 | 3070266 | 3089599 | 19334 | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_009525:2635792* | 2635792 | 2658641 | 22850 | Mycobacterium tuberculosis H37Ra, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_009525:3128786 | 3128786 | 3149047 | 20262 | Mycobacterium tuberculosis H37Ra, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_009565:3128094 | 3128094 | 3148237 | 20144 | Mycobacterium tuberculosis F11, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_009565:3485772 | 3485772 | 3504774 | 19003 | Mycobacterium tuberculosis F11, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_012207:3063039 | 3063039 | 3084779 | 21741 | Mycobacterium bovis BCG str. Tokyo 172, complete genome | 0 | 2678 | BLASTN svg | BLASTP svg |
NC_002755:472872 | 472872 | 496457 | 23586 | Mycobacterium tuberculosis CDC1551, complete genome | 0 | 2670 | BLASTN svg | BLASTP svg |
NC_009077:2308634* | 2308634 | 2356498 | 47865 | Mycobacterium sp. JLS, complete genome | 0 | 767 | BLASTN svg | BLASTP svg |
NC_002677:491043 | 491043 | 513273 | 22231 | Mycobacterium leprae TN, complete genome | 5e-23 | 117 | BLASTN svg | BLASTP svg |
NC_020133:4841932 | 4841932 | 4859924 | 17993 | Mycobacterium liflandii 128FXT, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_002755:831397 | 831397 | 850054 | 18658 | Mycobacterium tuberculosis CDC1551, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_002945:831029 | 831029 | 853656 | 22628 | Mycobacterium bovis AF2122/97, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_008769:860670 | 860670 | 879696 | 19027 | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_009525:830513 | 830513 | 849219 | 18707 | Mycobacterium tuberculosis H37Ra, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_009565:833076 | 833076 | 851782 | 18707 | Mycobacterium tuberculosis F11, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_012207:831030 | 831030 | 853609 | 22580 | Mycobacterium bovis BCG str. Tokyo 172, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_020133:1443934 | 1443934 | 1466099 | 22166 | Mycobacterium liflandii 128FXT, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_008435:1215437* | 1215437 | 1312091 | 96655 | Rhodopseudomonas palustris BisA53, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_013235:1354443 | 1354443 | 1374854 | 20412 | Nakamurella multipartita DSM 44233, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_013235:3812838* | 3812838 | 3841423 | 28586 | Nakamurella multipartita DSM 44233, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_014815:841484* | 841484 | 898099 | 56616 | Micromonospora sp. L5 chromosome, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_014814:2588628* | 2588628 | 2647576 | 58949 | Mycobacterium sp. Spyr1 chromosome, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_009525:3933567 | 3933567 | 3958929 | 25363 | Mycobacterium tuberculosis H37Ra, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_008752:3217695 | 3217695 | 3239549 | 21855 | Acidovorax avenae subsp. citrulli AAC00-1, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_008752:2936933 | 2936933 | 2978329 | 41397 | Acidovorax avenae subsp. citrulli AAC00-1, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_010125:1051735 | 1051735 | 1082599 | 30865 | Gluconacetobacter diazotrophicus PAl 5, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |