Pre_GI: BLASTP Hits

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Query: NC_017026:3282405:3298386 Mycobacterium tuberculosis RGTB327 chromosome, complete genome

Start: 3298386, End: 3299198, Length: 813

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016804:3221818:323796732379673238779813Mycobacterium bovis BCG str. Mexico chromosome, complete genomeputative methyltransferase8e-160562
NC_000962:3288464:330444133044413305253813Mycobacterium tuberculosis H37Rv, complete genomePOSSIBLE METHYLTRANSFERASE (METHYLASE)8e-160562
NC_002945:3246278:326112932611293261941813Mycobacterium bovis AF2122/97, complete genomemethyltransferase (methylase)8e-160562
NC_009525:3300456:331643333164333317245813Mycobacterium tuberculosis H37Ra, complete genomeputative methyltransferase8e-160562
NC_009565:3299937:331591433159143316726813Mycobacterium tuberculosis F11, complete genomehypothetical methyltransferase8e-160562
NC_008769:3242453:325860232586023259414813Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative methyltransferase8e-160562
NC_012207:3237440:325142932514293252241813Mycobacterium bovis BCG str. Tokyo 172, complete genomeputative methyltransferase8e-160562
NC_002755:3282785:329876232987623299574813Mycobacterium tuberculosis CDC1551, complete genomemethyltransferase, putative8e-160562
NC_019950:3306419:332537133253713326183813Mycobacterium canettii CIPT 140060008 complete genomePutative methyltransferase (methylase)3e-159560
NC_015848:3343731:336106233610623361874813Mycobacterium canettii CIPT 140010059, complete genomeputative methyltransferase3e-159560
NC_011896:173197:174493174493175305813Mycobacterium leprae Br4923, complete genomehypothetical protein5e-136483
NC_002677:173170:174466174466175278813Mycobacterium leprae TN, complete genomehypothetical protein5e-136483
NC_016804:1679357:1700273170027317013161044Mycobacterium bovis BCG str. Mexico chromosome, complete genomeputative methyltransferase4e-78291
NC_002945:1680751:1701666170166617027091044Mycobacterium bovis AF2122/97, complete genomemethyltransferase4e-78291
NC_008769:1709078:1729994172999417310371044Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative methyltransferase4e-78291
NC_012207:1681971:1702887170288717039301044Mycobacterium bovis BCG str. Tokyo 172, complete genomeputative methyltransferase4e-78291
NC_010397:4150596:416248541624854163288804Mycobacterium abscessus chromosome Chromosome, complete sequenceProbable methyltransferase1e-76286
NC_008596:421882:443164443164443967804Mycobacterium smegmatis str. MC2 155, complete genomeFmt protein2e-73275
NC_009664:3718927:374054237405423741309768Kineococcus radiotolerans SRS30216, complete genomeMethyltransferase type 111e-42172
NC_002944:4163490:419844241984424198828387Mycobacterium avium subsp. paratuberculosis K-10, complete genomehypothetical protein3e-40165
NC_014722:1647978:165799116579911658857867Burkholderia rhizoxinica HKI 454, complete genomemethyltransferase2e-35149
NC_008700:2451798:247197324719732472581609Shewanella amazonensis SB2B, complete genomeconserved hypothetical methyltransferase4e-1478.6
NC_015697:116000:132686132686133387702Lactobacillus reuteri SD2112 chromosome, complete genome2-heptaprenyl-1,4-naphthoquinone methyltransferase1e-1377
NC_009523:907775:926540926540927427888Roseiflexus sp. RS-1 chromosome, complete genometype 11 methyltransferase2e-1273.2
NC_013093:3791912:380528438052843806099816Actinosynnema mirum DSM 43827, complete genomeMethyltransferase type 113e-1169.3
NC_014844:762794:772362772362773180819Desulfovibrio aespoeensis Aspo-2 chromosome, complete genometype 11 methyltransferase3e-1169.3
NC_013743:1045488:106232510623251063146822Haloterrigena turkmenica DSM 5511, complete genomeMethyltransferase type 114e-1168.6
NC_016884:2194419:2218823221882322198961074Sulfobacillus acidophilus DSM 10332 chromosome, complete genometype 11 methyltransferase1e-1067.4
NC_015757:1329012:1331129133112913321541026Sulfobacillus acidophilus TPY chromosome, complete genomeglycosyl transferase family 21e-1067
NC_014507:863210:898390898390899118729Methanoplanus petrolearius DSM 11571 chromosome, complete genometype 11 methyltransferase2e-1066.6
NC_017904:3113000:312282331228233123479657Mycobacterium sp. MOTT36Y chromosome, complete genomemethyltransferase3e-1065.9
NC_018681:5378197:539746253974625398280819Nocardia brasiliensis ATCC 700358 chromosome, complete genomemethyltransferase type 116e-1064.7
NC_009523:5104413:5125245512524551283433099Roseiflexus sp. RS-1 chromosome, complete genomeglycosyl transferase family protein1e-0963.5
NC_009840:1485383:152166815216681522603936Prochlorococcus marinus str. MIT 9215, complete genomeSAM (and some other nucleotide) binding motif2e-0962.8
NC_018681:867230:889716889716890597882Nocardia brasiliensis ATCC 700358 chromosome, complete genomeputative methyltransferase3e-0962.8
NC_015564:2870631:287063128706312871470840Amycolicicoccus subflavus DQS3-9A1 chromosome, complete genomemethyltransferase3e-0962.4
NC_008343:823093:8438538438538474883636Granulibacter bethesdensis CGDNIH1, complete genomeglycosyltransferase6e-0961.6
NC_008816:1416711:145188714518871452822936Prochlorococcus marinus str. AS9601, complete genomeSAM (and some other nucleotide) binding motif7e-0961.2
NC_005125:4524868:4537024453702445382261203Gloeobacter violaceus PCC 7421, complete genomehypothetical protein8e-0961.2
NC_007802:1991211:202540220254022026187786Jannaschia sp. CCS1, complete genomeMethyltransferase type 111e-0860.8
NC_009467:117812:129492129492130319828Acidiphilium cryptum JF-5 plasmid pACRY01, complete sequencemethyltransferase type 111e-0860.8
NC_015680:1475917:149444214944421495170729Pyrococcus yayanosii CH1 chromosome, complete genomesterol biosynthesis methyltransferase-like protein1e-0860.8
NC_009091:1423677:142898614289861429918933Prochlorococcus marinus str. MIT 9301, complete genomeSAM (and some other nucleotide) binding motif9e-0960.8
NC_003450:1395565:142006814200681420847780Corynebacterium glutamicum ATCC 13032, complete genomeSAM-dependent methyltransferase2e-0860.1
NC_007802:3807500:380919138091913809913723Jannaschia sp. CCS1, complete genomeMethyltransferase type 112e-0859.7
NC_015873:1411718:143111214311121431762651Megasphaera elsdenii DSM 20460, complete genomeSAM-dependent methyltransferase2e-0859.7
NC_020911:3475096:347509634750963475815720Octadecabacter antarcticus 307, complete genome3-demethylubiquinone-9 3-methyltransferase UbiG2e-0859.7
NC_011884:3881568:389205338920533892859807Cyanothece sp. PCC 7425, complete genomeMethyltransferase type 112e-0859.7
NC_009637:1421885:142430414243041425161858Methanococcus maripaludis C7 chromosome, complete genometype 11 methyltransferase2e-0859.7
NC_002570:2649759:265406626540662654728663Bacillus halodurans C-125, complete genomehypothetical protein2e-0859.7
NC_013159:2913927:2919884291988429215631680Saccharomonospora viridis DSM 43017, complete genomeglycine/sarcosine N-methyltransferase2e-0859.7
NC_020911:4428000:443902044390204439730711Octadecabacter antarcticus 307, complete genome3-demethylubiquinone-9 3-methyltransferase UbiG3e-0859.3
NC_013790:2131000:213142521314252132093669Methanobrevibacter ruminantium M1 chromosome, complete genomeSAM-dependent methyltransferase3e-0859.3
NC_014840:205723:230082230082230753672Pantoea sp. At-9b plasmid pPAT9B03, complete sequencemethyltransferase type 113e-0859.3
NC_008817:1476473:148180114818011482736936Prochlorococcus marinus str. MIT 9515, complete genomeSAM (and some other nucleotide) binding motif4e-0858.9
NC_016002:2453919:248205524820552482999945Pseudogulbenkiania sp. NH8B, complete genometype 11 methyltransferase3e-0858.9
NC_015311:1827000:183976618397661840467702Prevotella denticola F0289 chromosome, complete genomemethyltransferase domain-containing protein3e-0858.9
NC_015671:255808:295006295006295623618Cellvibrio gilvus ATCC 13127 chromosome, complete genometype 11 methyltransferase5e-0858.5
NC_008789:1669082:167716016771601677939780Halorhodospira halophila SL1, complete genomeMethyltransferase type 115e-0858.5
NC_011060:459615:475244475244475993750Pelodictyon phaeoclathratiforme BU-1, complete genomeubiquinone/menaquinone biosynthesis methyltransferase6e-0858.2
NC_015508:251354:2577452577452608133069Agrobacterium sp. H13-3 chromosome linear, complete sequenceglycosyltransferase8e-0857.8
NC_006663:1:100551005510789735Staphylococcus epidermidis RP62A plasmid pSERP, complete sequencemethyltransferase, UbiE/COQ5 family8e-0857.8
NC_009442:908507:927674927674928408735Streptococcus suis 05ZYH33 chromosome, complete genomehypothetical protein8e-0857.8
NC_013093:3791912:380450238045023805287786Actinosynnema mirum DSM 43827, complete genomeMethyltransferase type 118e-0857.8
NC_020409:2856481:287012728701272871005879Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completehypothetical protein7e-0857.8
NC_003155:622993:631817631817632638822Streptomyces avermitilis MA-4680, complete genomeubiE/COQ5 methyltransferase family protein7e-0857.8
NC_015589:2209011:222753422275342228121588Desulfotomaculum ruminis DSM 2154 chromosome, complete genometype 11 methyltransferase7e-0857.8
NC_003413:128228:147057147057147743687Pyrococcus furiosus DSM 3638, complete genomeputative methyltransferase9e-0857.4
NC_003551:1678882:168718216871821687805624Methanopyrus kandleri AV19, complete genomeSAM-dependent methyltransferase9e-0857.4
NC_008699:4443000:445952244595224460307786Nocardioides sp. JS614, complete genomeMethyltransferase type 112e-0757
NC_000911:15937:290982909829895798Synechocystis sp. PCC 6803, complete genomehypothetical protein1e-0757
NC_017039:15937:290982909829895798Synechocystis sp. PCC 6803 substr. PCC-P, complete genomehypothetical protein1e-0757
NC_017052:15937:290982909829895798Synechocystis sp. PCC 6803 substr. PCC-N, complete genomehypothetical protein1e-0757
NC_017277:15937:290982909829895798Synechocystis sp. PCC 6803, complete genomehypothetical protein1e-0757
NC_014828:1019533:104646710464671047099633Ethanoligenens harbinense YUAN-3 chromosome, complete genomeMethyltransferase type 111e-0757
NC_017093:1411532:143225814322581433055798Actinoplanes missouriensis 431, complete genomeputative ubiquinone/menaquinone methyltransferase1e-0757
NC_009635:518000:521284521284521991708Methanococcus aeolicus Nankai-3 chromosome, complete genomemethyltransferase type 111e-0757
NC_014100:449541:448624448624449544921Caulobacter segnis ATCC 21756 chromosome, complete genomemethyltransferase type 112e-0756.6
NC_013132:8871718:887297688729768873710735Chitinophaga pinensis DSM 2588, complete genomeubiquinone/menaquinone biosynthesis methyltransferase2e-0756.6
NC_013440:5944935:5954874595487459561211248Haliangium ochraceum DSM 14365, complete genomeMethyltransferase type 112e-0756.6
NC_014507:906960:906960906960907724765Methanoplanus petrolearius DSM 11571 chromosome, complete genometype 11 methyltransferase2e-0756.6
NC_009925:4864367:486436748643674865353987Acaryochloris marina MBIC11017, complete genomecyclopropane-fatty-acyl-phospholipid synthase2e-0756.6
NC_017506:2993679:299915229991522999862711Marinobacter adhaerens HP15 chromosome, complete genomemethyltransferase2e-0756.2
NC_000917:270500:2828472828472863753529Archaeoglobus fulgidus DSM 4304, complete genome2e-0756.2
NC_020389:2245368:225579022557902256380591Methanosarcina mazei Tuc01, complete genomeGlycosyltransferase2e-0756.2
NC_003901:2626426:2634042263404226381844143Methanosarcina mazei Go1, complete genomeputative glycosyltransferase2e-0756.2
NC_000868:196015:214479214479215162684Pyrococcus abyssi GE5, complete genomesterol biosynthesis methyltransferase related2e-0756.2
NC_019968:1235500:126356412635641264277714Prevotella dentalis DSM 3688 chromosome 2, complete sequencemethylase involved in ubiquinone/menaquinone biosynthesis3e-0755.8
NC_009635:518000:530478530478531110633Methanococcus aeolicus Nankai-3 chromosome, complete genomemethyltransferase type 113e-0755.8
NC_018681:5490963:551724555172455517922678Nocardia brasiliensis ATCC 700358 chromosome, complete genomemethyltransferase4e-0755.5
NC_020291:2218425:223041122304112231037627Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomemethylase involved in ubiquinone/menaquinone biosynthesis4e-0755.5
NC_013521:2193203:219320321932032193805603Sanguibacter keddieii DSM 10542, complete genomeubiquinone/menaquinone biosynthesis methylase4e-0755.5
NC_013960:3379515:340458934045893405260672Nitrosococcus halophilus Nc4 chromosome, complete genomeMethyltransferase type 114e-0755.5
NC_013517:1055854:108469010846901085430741Sebaldella termitidis ATCC 33386, complete genomeMethyltransferase type 114e-0755.5
NC_009486:155651:171626171626172288663Thermotoga petrophila RKU-1 chromosome, complete genomeubiquinone/menaquinone biosynthesis methyltransferase4e-0755.5
NC_007604:1442500:145991414599141460555642Synechococcus elongatus PCC 7942, complete genomemembrane-associated protein4e-0755.5
NC_008095:8837612:884938288493828850272891Myxococcus xanthus DK 1622, complete genomehypothetical protein4e-0755.5
NC_008312:5903000:5919177591917759202681092Trichodesmium erythraeum IMS101, complete genomeMethyltransferase type 114e-0755.5
NC_013642:545464:549680549680550342663Thermotoga naphthophila RKU-10, complete genomeubiquinone/menaquinone biosynthesis methyltransferase4e-0755.5
NC_014622:5683400:568701356870135687777765Paenibacillus polymyxa SC2 chromosome, complete genomehypothetical protein6e-0755.1
NC_009706:2673906:269039326903932691133741Clostridium kluyveri DSM 555 chromosome, complete genomemethyltransferase6e-0755.1
NC_011837:2605409:262189626218962622636741Clostridium kluyveri NBRC 12016, complete genomehypothetical protein6e-0755.1
NC_016887:5607272:560727256072725607904633Nocardia cyriacigeorgica GUH-2, complete genomeputative Methyltransferase6e-0755.1
NC_011898:3367457:336745733674573368197741Clostridium cellulolyticum H10, complete genomeMethyltransferase type 115e-0755.1
NC_006624:2016000:203209420320942032780687Thermococcus kodakarensis KOD1, complete genomeSAM-dependent methyltransferase, UbiE/COQ5 family5e-0755.1
NC_007347:767455:7774837774837808033321Ralstonia eutropha JMP134 chromosome 1, complete sequenceGlycosyl transferase, family 2:Glycosyl transferase, group 15e-0755.1
NC_014378:261064:2682542682542706202367Acetohalobium arabaticum DSM 5501 chromosome, complete genomeMethyltransferase type 115e-0755.1
NC_007517:3344799:334813733481373348973837Geobacter metallireducens GS-15, complete genomehypothetical protein7e-0754.7
NC_014804:1183780:119857711985771199185609Thermococcus barophilus MP chromosome, complete genomeubiquinone/menaquinone biosynthesis methyltransferase7e-0754.7
NC_014844:762794:776867776867777613747Desulfovibrio aespoeensis Aspo-2 chromosome, complete genometype 11 methyltransferase7e-0754.7
NC_003240:137907:146950146950147525576Nostoc sp. PCC 7120 plasmid pCC7120beta, complete sequencehypothetical protein6e-0754.7
NC_016641:1530905:154436315443631545133771Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein9e-0754.3
NC_017030:4062699:407712640771264078094969Corallococcus coralloides DSM 2259 chromosome, complete genometype 11 methyltransferase9e-0754.3
NC_014655:424486:454401454401455132732Leadbetterella byssophila DSM 17132 chromosome, complete genomemethyltransferase type 111e-0653.9
NC_015589:2878000:289659528965952897329735Desulfotomaculum ruminis DSM 2154 chromosome, complete genometype 11 methyltransferase1e-0653.9
NC_016887:3286436:330251433025143303320807Nocardia cyriacigeorgica GUH-2, complete genomehypothetical protein1e-0653.9
NC_007907:4926548:493664949366494937314666Desulfitobacterium hafniense Y51, complete genomehypothetical protein1e-0653.9
NC_011830:1037520:106988710698871070552666Desulfitobacterium hafniense DCB-2, complete genomeMethyltransferase type 111e-0653.9
NC_011894:6888562:694564669456466946569924Methylobacterium nodulans ORS 2060, complete genomeMethyltransferase type 111e-0653.9
NC_019974:2960872:297027529702752971003729Natronococcus occultus SP4, complete genomemethylase involved in ubiquinone/menaquinone biosynthesis1e-0653.9
NC_016111:1546505:156020715602071561055849Streptomyces cattleya NRRL 8057, complete genomeD-glucose O-methyltransferase1e-0653.5
NC_003911:633393:638752638752639378627Silicibacter pomeroyi DSS-3, complete genomehypothetical protein1e-0653.5
NC_008508:1382036:139473413947341395468735Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1,Methylase/methyltransferase2e-0653.1
NC_008510:1339926:135261513526151353349735Leptospira borgpetersenii serovar Hardjo-bovis JB197 chromosome 1,Methylase/methyltransferase2e-0653.1
NC_015500:1236874:125340012534001254050651Treponema brennaborense DSM 12168 chromosome, complete genomeMethyltransferase type 112e-0653.1
NC_008278:2813362:282974928297492830459711Frankia alni ACN14a, complete genomehypothetical protein2e-0653.1
NC_015856:940625:969089969089969964876Collimonas fungivorans Ter331 chromosome, complete genomeputative glycosyltransferase2e-0653.1
NC_011894:7109374:712853671285367129294759Methylobacterium nodulans ORS 2060, complete genomeubiquinone/menaquinone biosynthesis methyltransferase2e-0653.1
NC_003552:4782635:480040848004084801163756Methanosarcina acetivorans C2A, complete genomeubiE/COQ5 methyltransferase2e-0653.1
NC_021177:2139838:214090821409082141639732Streptomyces fulvissimus DSM 40593, complete genomeMethyltransferase2e-0653.1
NC_014623:7482229:752914875291487529945798Stigmatella aurantiaca DW4/3-1 chromosome, complete genometype 11 methyltransferase2e-0652.8
NC_008699:3516608:353441835344183535050633Nocardioides sp. JS614, complete genomeMethyltransferase type 113e-0652.4
NC_002678:7004370:701465070146507015393744Mesorhizobium loti MAFF303099, complete genomehypothetical protein3e-0652.4
NC_014023:24000:438634386344597735Bacillus megaterium QM B1551 plasmid pBM700, complete sequencemethyltransferase domain protein5e-0652
NC_011658:3438102:343810234381023439049948Bacillus cereus AH187 chromosome, complete genomehypothetical protein4e-0652
NC_016771:3386660:339060033906003391547948Bacillus cereus NC7401, complete genomehypothetical protein4e-0652
NC_015573:2040500:205804620580462058735690Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genometype 11 methyltransferase4e-0652
NC_006274:3490598:349059834905983491554957Bacillus cereus E33L, complete genomepossible ubiquinone/menaquinone methyltransferase5e-0651.6
NC_011969:3401916:340191634019163402863948Bacillus cereus Q1 chromosome, complete genomeubiquinone/menaquinone methyltransferase6e-0651.6
NC_007759:1356439:1388643138864313919033261Syntrophus aciditrophicus SB, complete genometetratricopeptide repeat domain with UbiE methylase6e-0651.6
NC_014355:3398033:3411960341196034158173858Candidatus Nitrospira defluvii, complete genomeputative methyltransferase and glycosyltransferase6e-0651.6