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Query: NC_016914:278500:283283 Rickettsia rickettsii str. Hino chromosome, complete genome

Start: 283283, End: 283468, Length: 186

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016915:278000:282832282832283017186Rickettsia rickettsii str. Hlp#2 chromosome, complete genomehypothetical protein6e-26115
NC_016913:859931:885723885723885908186Rickettsia rickettsii str. Brazil chromosome, complete genomehypothetical protein6e-26115
NC_016911:278415:283150283150283335186Rickettsia rickettsii str. Hauke chromosome, complete genomehypothetical protein6e-26115
NC_016909:278327:283062283062283247186Rickettsia rickettsii str. Arizona chromosome, complete genomehypothetical protein6e-26115
NC_016908:278457:283189283189283374186Rickettsia rickettsii str. Colombia chromosome, complete genomehypothetical protein6e-26115
NC_010263:278463:283197283197283382186Rickettsia rickettsii str. Iowa, complete genomehypothetical protein6e-26115
NC_017043:990395:100048210004821000667186Rickettsia montanensis str. OSU 85-930 chromosome, complete genomehypothetical protein3e-25114
NC_009882:278384:283121283121283303183Rickettsia rickettsii str. 'Sheila Smith', complete genomehypothetical protein2e-25114
NC_015866:274550:284549284549284734186Rickettsia heilongjiangensis 054 chromosome, complete genomehypothetical protein2e-25114
NC_003103:266013:278869278869279054186Rickettsia conorii str. Malish 7, complete genomehypothetical protein2e-25114
NC_012633:276500:281251281251281436186Rickettsia africae ESF-5, complete genomehypothetical protein2e-25114
NC_017044:278500:283353283353283538186Rickettsia parkeri str. Portsmouth chromosome, complete genomehypothetical protein2e-25114
NC_017065:274165:284036284036284221186Rickettsia slovaca str. D-CWPP chromosome, complete genomehypothetical protein2e-25114
NC_016639:274157:284031284031284213183Rickettsia slovaca 13-B chromosome, complete genomehypothetical protein6e-25112
NC_016931:269537:276063276063276248186Rickettsia massiliae str. AZT80 chromosome, complete genomehypothetical protein7e-25112
NC_012730:293634:307435307435307620186Rickettsia peacockii str. Rustic, complete genomehypothetical protein1e-24111
NC_017058:1152361:116561411656141165799186Rickettsia australis str. Cutlack chromosome, complete genomehypothetical protein3e-23107
NC_009881:283500:285238285238285420183Rickettsia akari str. Hartford, complete genomehypothetical protein2e-21100
NC_016929:258500:265930265930266103174Rickettsia canadensis str. CA410 chromosome, complete genomehypothetical protein6e-1889.4
NC_009879:260000:266245266245266418174Rickettsia canadensis str. McKiel, complete genomehypothetical protein6e-1889.4