Pre_GI: BLASTP Hits

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Query: NC_016913:917500:926853 Rickettsia rickettsii str. Brazil chromosome, complete genome

Start: 926853, End: 928343, Length: 1491

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:231324:2408582408582423481491Rickettsia rickettsii str. Hino chromosome, complete genomethermostable carboxypeptidase0941
NC_016911:232481:2407192407192422091491Rickettsia rickettsii str. Hauke chromosome, complete genomethermostable carboxypeptidase0941
NC_016909:230000:2406312406312421211491Rickettsia rickettsii str. Arizona chromosome, complete genomethermostable carboxypeptidase0941
NC_009882:232400:2406772406772421671491Rickettsia rickettsii str. 'Sheila Smith', complete genomethermostable carboxypeptidase0941
NC_010263:232482:2407712407712422611491Rickettsia rickettsii str. Iowa, complete genomethermostable carboxypeptidase 10941
NC_016930:228000:2387072387072401971491Rickettsia philipii str. 364D chromosome, complete genomethermostable carboxypeptidase0930
NC_003103:225956:2368982368982383881491Rickettsia conorii str. Malish 7, complete genomethermostable carboxypeptidase0917
NC_012730:332500:3414383414383429281491Rickettsia peacockii str. Rustic, complete genomethermostable carboxypeptidase0916
NC_017028:316000:3239723239723254621491Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completethermostable carboxypeptidase0914
NC_016050:236000:2439042439042453941491Rickettsia japonica YH, complete genomethermostable carboxypeptidase0913
NC_015866:233448:2429592429592444491491Rickettsia heilongjiangensis 054 chromosome, complete genomethermostable carboxypeptidase0907
NC_017058:1200500:1209338120933812108251488Rickettsia australis str. Cutlack chromosome, complete genomethermostable carboxypeptidase0865
NC_009881:236500:2445802445802460671488Rickettsia akari str. Hartford, complete genomethermostable carboxypeptidase0862
NC_009883:343067:3519893519893534761488Rickettsia bellii OSU 85-389, complete genomeThermostable carboxypeptidase0780
NC_007940:1178000:1188665118866511902091545Rickettsia bellii RML369-C, complete genomeThermostable carboxypeptidase0776
NC_017048:547712:5590885590885605781491Rickettsia prowazekii str. GvV257 chromosome, complete genomethermostable carboxypeptidase0768
NC_017057:205771:2171472171472186371491Rickettsia prowazekii str. RpGvF24 chromosome, complete genomethermostable carboxypeptidase0768
NC_017056:205558:2169322169322184221491Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomethermostable carboxypeptidase0768
NC_009879:200419:2095522095522109461395Rickettsia canadensis str. McKiel, complete genomemolecular chaperone DnaK0763
NC_016929:197403:2105412105412119351395Rickettsia canadensis str. CA410 chromosome, complete genomethermostable carboxypeptidase0756
NC_010830:1069666:1096513109651310980181506Candidatus Amoebophilus asiaticus 5a2, complete genomehypothetical protein1e-136486
NC_000963:205546:2169202169202184131494Rickettsia prowazekii str. Madrid E, complete genome1e-118426
NC_010725:356609:3725323725323740281497Methylobacterium populi BJ001, complete genomeCarboxypeptidase Taq3e-105382
NC_016445:984856:9848569848569864271572Vibrio cholerae O1 str. 2010EL-1786 chromosome 1, completecarboxypeptidase Taq8e-105381
NC_012668:2115228:2134664213466421362111548Vibrio cholerae MJ-1236 chromosome 1, complete sequencethermostable carboxypeptidase 11e-104380
NC_016944:1504888:1504888150488815063721485Vibrio cholerae IEC224 chromosome I, complete sequencethermostable carboxypeptidase 19e-105380
NC_002505:1507860:1507860150786015094341575Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, completethermostable carboxypeptidase 18e-105380
NC_012578:1465302:1465302146530214668761575Vibrio cholerae M66-2 chromosome I, complete sequencethermostable carboxypeptidase 18e-105380
NC_011757:276953:2985992985993000921494Methylobacterium chloromethanicum CM4, complete genomeCarboxypeptidase Taq3e-102372
NC_012808:157156:1761631761631776951533Methylobacterium extorquens AM1, complete genomeputative Zn dependent carboxypeptidase9e-102370
NC_016602:2037162:2055276205527620567601485Vibrio furnissii NCTC 11218 chromosome 1, complete sequencethermostable carboxypeptidase 11e-101370
NC_015424:3520783:3568809356880935702871479Aeromonas veronii B565 chromosome, complete genomeThermostable carboxypeptidase 13e-100366
NC_013508:1862896:1864983186498318664911509Edwardsiella tarda EIB202, complete genomeZn-dependent carboxypeptidase2e-99363
NC_016613:1805907:1826951182695118284321482Vibrio sp. EJY3 chromosome 1, complete sequencethermostable carboxypeptidase 16e-99361
NC_009900:231983:243736243736244317582Rickettsia massiliae MTU5, complete genome2e-98360
NC_004088:2366000:2366029236602923675281500Yersinia pestis KIM, complete genomecarboxypeptidase7e-96351
NC_012214:1974500:1974790197479019762741485Erwinia pyrifoliae Ep1/96, complete genomePutative carboxypeptidase7e-95348
NC_013971:1927510:1941899194189919433831485Erwinia amylovora ATCC 49946 chromosome, complete genomecarboxypeptidase1e-94347
NC_013961:1891000:1904372190437219058561485Erwinia amylovora, complete genomeputative carboxypeptidase1e-94347
NC_011830:3081726:3098514309851431000221509Desulfitobacterium hafniense DCB-2, complete genomeCarboxypeptidase Taq9e-74278
NC_021182:93000:1115841115841130951512Clostridium pasteurianum BC1, complete genomeZn-dependent carboxypeptidase3e-73276
NC_010003:225420:2254202254202269191500Petrotoga mobilis SJ95, complete genomeCarboxypeptidase Taq3e-72272
NC_014205:760428:7750567750567765491494Staphylothermus hellenicus DSM 12710 chromosome, complete genomeCarboxypeptidase Taq6e-72271
NC_000961:372000:4255614255614271081548Pyrococcus horikoshii OT3, complete genomethermostable carboxypeptidase9e-71268
NC_014393:92500:1057511057511072471497Clostridium cellulovorans 743B chromosome, complete genomeCarboxypeptidase Taq1e-69264
NC_012785:1960500:1960660196066019621621503Kosmotoga olearia TBF 19.5.1, complete genomeCarboxypeptidase Taq2e-69263
NC_016629:3396500:3418191341819134196961506Desulfovibrio africanus str. Walvis Bay chromosome, completeCarboxypeptidase Taq2e-67256
NC_017191:1173989:1176933117693311784351503Bacillus amyloliquefaciens XH7 chromosome, complete genomemetal-dependent carboxypeptidase3e-67256
NC_017190:2130651:2280629228062922821311503Bacillus amyloliquefaciens LL3 chromosome, complete genomemetal-dependent carboxypeptidase3e-67256
NC_017188:1172181:1175356117535611768581503Bacillus amyloliquefaciens TA208 chromosome, complete genomemetal-dependent carboxypeptidase3e-67256
NC_020291:6274030:6281254628125462827651512Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeZn-dependent carboxypeptidase2e-66253
NC_014958:629459:6492356492356507341500Deinococcus maricopensis DSM 21211 chromosome, complete genomecarboxypeptidase Taq4e-62239
NC_016070:743255:7644647644647659391476Thermoproteus tenax Kra 1, complete genomeZn-dependent carboxypeptidase1e-61238
NC_009718:643200:6535236535236549951473Fervidobacterium nodosum Rt17-B1, complete genomecarboxypeptidase Taq8e-62238
NC_008025:316302:3360113360113375041494Deinococcus geothermalis DSM 11300, complete genomeThermostable carboxypeptidase 11e-60234
NC_008245:1845525:1863661186366118649891329Francisella tularensis subsp. tularensis FSC 198, complete genome1e-60234
NC_009257:5615:7519751989431425Francisella tularensis subsp. tularensis WY96-3418 chromosome,metallocarboxypeptidase4e-60232
NC_009050:604950:6049506049506064311482Rhodobacter sphaeroides ATCC 17029 chromosome 2, complete sequenceCarboxypeptidase Taq5e-60232
NC_007494:27084:2708427084285651482Rhodobacter sphaeroides 2.4.1 chromosome 2, complete sequenceputative thermostable carboxypeptidase 15e-60232
NC_016937:1850382:1863731186373118665652835Francisella tularensis subsp. tularensis TI0902 chromosome,Thermostable carboxypeptidase 18e-60231
NC_008369:82515:9503495034965391506Francisella tularensis subsp. holarctica OSU18, complete genomeprobable carboxypeptidase2e-59230
NC_003454:677699:6971596971596986491491Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeThermostable carboxypeptidase 19e-59228
NC_009749:77583:9509295092965161425Francisella tularensis subsp. holarctica FTA, complete genomethermostable carboxypeptidase 18e-59228
NC_012526:2483000:2483177248317724846581482Deinococcus deserti VCD115, complete genomeputative carboxypeptidase Taq (Thermostable carboxypeptidase 1)2e-58227
NC_009481:1638394:1654614165461416561461533Synechococcus sp. WH 7803 chromosome, complete genomeZn-dependent carboxypeptidase6e-53208
NC_015601:1107961:1141642114164211431111470Erysipelothrix rhusiopathiae str. Fujisawa, complete genomecarboxypeptidase Taq family4e-52206
NC_015152:3100312:3124541312454131260251485Spirochaeta sp. Buddy chromosome, complete genomecarboxypeptidase Taq1e-46188
NC_017050:205547:218079218079218414336Rickettsia prowazekii str. Katsinyian chromosome, complete genomethermostable carboxypeptidase3e-36153
NC_009900:231983:244377244377244508132Rickettsia massiliae MTU5, complete genome8e-1685.5