Pre_GI: BLASTP Hits

Some Help

Query: NC_016913:917500:924016 Rickettsia rickettsii str. Brazil chromosome, complete genome

Start: 924016, End: 924108, Length: 93

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:231324:245093245093245272180Rickettsia rickettsii str. Hino chromosome, complete genomecation transport regulator1e-1065.5
NC_016911:232481:244954244954245133180Rickettsia rickettsii str. Hauke chromosome, complete genomecation transport regulator1e-1065.5
NC_016909:230000:244866244866245045180Rickettsia rickettsii str. Arizona chromosome, complete genomecation transport regulator1e-1065.5
NC_010263:232482:245006245006245185180Rickettsia rickettsii str. Iowa, complete genomecation transport regulator1e-1065.5
NC_009882:232400:24491224491224500493Rickettsia rickettsii str. 'Sheila Smith', complete genomehypothetical protein1e-1065.1
NC_015866:233448:247167247167247295129Rickettsia heilongjiangensis 054 chromosome, complete genomeCation transport regulator ChaB1e-0961.6
NC_003103:225956:241198241198241368171Rickettsia conorii str. Malish 7, complete genomesimilarity to cation transport regulator ChaB2e-0961.6
NC_016930:228000:242896242896243033138Rickettsia philipii str. 364D chromosome, complete genomecation transport regulator ChaB2e-0960.8
NC_017028:316000:328203328203328400198Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completecation transport regulator ChaB3e-0650.4