Pre_GI: BLASTP Hits

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Query: NC_016913:917500:917648 Rickettsia rickettsii str. Brazil chromosome, complete genome

Start: 917648, End: 917989, Length: 342

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:231324:251204251204251545342Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein2e-58224
NC_016930:228000:249061249061249402342Rickettsia philipii str. 364D chromosome, complete genomehypothetical protein5e-53206
NC_003103:225956:247351247351247698348Rickettsia conorii str. Malish 7, complete genomehypothetical protein3e-48190
NC_016050:236000:253902253902254249348Rickettsia japonica YH, complete genomehypothetical protein2e-42170
NC_017042:310000:331557331557331904348Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, completehypothetical protein6e-37152
NC_015866:233448:252829252829253122294Rickettsia heilongjiangensis 054 chromosome, complete genomehypothetical protein2e-34144
NC_009881:236500:255508255508255852345Rickettsia akari str. Hartford, complete genomehypothetical protein3e-28124
NC_009879:200419:200419200419200691273Rickettsia canadensis str. McKiel, complete genomehypothetical protein3e-2097.1
NC_016929:197403:201336201336201662327Rickettsia canadensis str. CA410 chromosome, complete genomehypothetical protein4e-1993.2
NC_009883:343067:344507344507344800294Rickettsia bellii OSU 85-389, complete genomehypothetical protein1e-0962
NC_007940:1178000:119727811972781197634357Rickettsia bellii RML369-C, complete genomehypothetical protein1e-0962