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Query: NC_016913:24000:28359 Rickettsia rickettsii str. Brazil chromosome, complete genome

Start: 28359, End: 28631, Length: 273

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016930:1154500:117095411709541171226273Rickettsia philipii str. 364D chromosome, complete genomebeta-lactamase2e-48190
NC_010263:1135932:115168211516821151954273Rickettsia rickettsii str. Iowa, complete genomebeta-lactamase2e-48190
NC_009882:1123709:114012511401251140397273Rickettsia rickettsii str. 'Sheila Smith', complete genomehypothetical protein2e-48190
NC_016908:1136082:115183011518301152102273Rickettsia rickettsii str. Colombia chromosome, complete genomebeta-lactamase2e-48190
NC_016909:1136210:115196011519601152232273Rickettsia rickettsii str. Arizona chromosome, complete genomebeta-lactamase2e-48190
NC_016911:1136584:115233411523341152606273Rickettsia rickettsii str. Hauke chromosome, complete genomebeta-lactamase2e-48190
NC_016914:1136700:115245011524501152722273Rickettsia rickettsii str. Hino chromosome, complete genomebeta-lactamase2e-48190
NC_012633:1145500:115983911598391160552714Rickettsia africae ESF-5, complete genome8e-48188
NC_003103:1133806:115026611502661150538273Rickettsia conorii str. Malish 7, complete genomesimilarity to beta-lactamase2e-47187
NC_017065:1144500:115925911592591159531273Rickettsia slovaca str. D-CWPP chromosome, complete genomebeta-lactamase7e-47185
NC_015866:1144958:116446311644631164735273Rickettsia heilongjiangensis 054 chromosome, complete genomeputative beta-lactamase2e-46184
NC_007109:1335037:135414913541491354949801Rickettsia felis URRWXCal2, complete genomeBeta-lactamase Class D7e-42169
NC_007940:97949:122469122469123269801Rickettsia bellii RML369-C, complete genomeClass D beta-lactamase3e-40163
NC_017028:1348865:136654913665491366743195Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completeputative beta-lactamase2e-22104
NC_007650:420745:443933443933444742810Burkholderia thailandensis E264 chromosome II, complete sequencebeta-lactamase precursor6e-1992.8
NC_015376:1185000:119773711977371198543807Burkholderia gladioli BSR3 chromosome chromosome 2, completeBeta-lactamase3e-1787.4
NC_016860:4055117:407397340739734074848876Salmonella enterica subsp. enterica serovar Typhimurium strbeta-lactamase OXA-12e-1064.7
NC_017328:1075535:111008811100881110918831Shigella flexneri 2002017 chromosome, complete genomeOxacillinase2e-1064.7
NC_009900:1220082:123759712375971237824228Rickettsia massiliae MTU5, complete genome1e-0962
NC_014366:588347:604821604821605651831Gamma proteobacterium HdN1, complete genomebeta-lactamase class D (Penicillin-binding protein) (OXA-9)4e-0960.1
NC_010611:240839:251962251962252762801Acinetobacter baumannii ACICU, complete genomeBeta-lactamase class D2e-0754.3
NC_008609:142471:184864184864185730867Pelobacter propionicus DSM 2379, complete genomeBeta-lactamase4e-0650.1