Pre_GI: BLASTP Hits

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Query: NC_016913:1066790:1080689 Rickettsia rickettsii str. Brazil chromosome, complete genome

Start: 1080689, End: 1081021, Length: 333

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012730:411526:428607428607428939333Rickettsia peacockii str. Rustic, complete genomeHesB protein family protein4e-59226
NC_017044:80384:889658896589297333Rickettsia parkeri str. Portsmouth chromosome, complete genomeIron-sulfur cluster assembly accessory protein5e-59225
NC_016931:107880:114397114397114729333Rickettsia massiliae str. AZT80 chromosome, complete genomeHesB protein family protein1e-58224
NC_003103:70000:856588565885990333Rickettsia conorii str. Malish 7, complete genomehesB protein2e-58223
NC_009900:73804:895228952289854333Rickettsia massiliae MTU5, complete genomeIron-sulfur cluster assembly accessory protein4e-58222
NC_016050:73993:908729087291204333Rickettsia japonica YH, complete genomeiron-sulfur cluster assembly accessory protein5e-58222
NC_009881:70807:809668096681298333Rickettsia akari str. Hartford, complete genomeIron-sulfur cluster assembly accessory protein9e-56214
NC_017058:97810:116300116300116629330Rickettsia australis str. Cutlack chromosome, complete genomeIron-sulfur cluster assembly accessory protein6e-55212
NC_017056:58000:713437134371675333Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomeHESB protein (hesB1)3e-54209
NC_017051:58000:713487134871680333Rickettsia prowazekii str. Dachau chromosome, complete genomeHESB protein (hesB1)3e-54209
NC_017049:58000:713467134671678333Rickettsia prowazekii str. Chernikova chromosome, complete genomeHESB protein (hesB1)3e-54209
NC_017048:400000:413276413276413608333Rickettsia prowazekii str. GvV257 chromosome, complete genomeHESB protein (hesB1)3e-54209
NC_016929:55974:706147061470946333Rickettsia canadensis str. CA410 chromosome, complete genome2-dehydro-3-deoxyphosphooctonate aldolase3e-53206
NC_009879:57500:698656986570197333Rickettsia canadensis str. McKiel, complete genome2-dehydro-3-deoxyphosphooctonate aldolase1e-52204
NC_010511:2703684:273383127338312734157327Methylobacterium sp. 4-46 chromosome, complete genomeiron-sulfur cluster assembly accessory protein1e-1995.5
NC_008340:480399:483341483341483709369Alkalilimnicola ehrlichei MLHE-1, complete genomeiron-sulfur cluster assembly accessory protein4e-1993.2
NC_010939:1633000:163771416377141638055342Actinobacillus pleuropneumoniae serovar 7 str. AP76, completehypothetical protein2e-1891.3
NC_009053:1668500:167551216755121675853342Actinobacillus pleuropneumoniae L20, complete genomehypothetical protein2e-1890.9
NC_010278:1625695:163268516326851633026342Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,iron-sulfur cluster insertion protein ErpA4e-1889.7
NC_011601:149428:187370187370187714345Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomeiron-sulfur cluster insertion protein ErpA1e-1788.6
NC_010336:213148:242390242390242740351Francisella philomiragia subsp. philomiragia ATCC 25017, completehypothetical protein2e-1788.2
NC_013166:417862:421665421665421991327Kangiella koreensis DSM 16069, complete genomeiron-sulfur cluster assembly accessory protein1e-1788.2
NC_008601:631504:643949643949644299351Francisella tularensis subsp. novicida U112, complete genomehypothetical protein2e-1787.4
NC_008245:707984:720035720035720385351Francisella tularensis subsp. tularensis FSC 198, complete genomehypothetical protein2e-1787.4
NC_007880:1456705:146506714650671465417351Francisella tularensis subsp. holarctica, complete genomehypothetical protein2e-1787.4
NC_016933:783938:795989795989796339351Francisella tularensis TIGB03 chromosome, complete genomeputative iron binding protein from the HesB_IscA_SufA family2e-1787.4
NC_016937:707279:720082720082720432351Francisella tularensis subsp. tularensis TI0902 chromosome,putative iron binding protein from the HesB_IscA_SufA family2e-1787.4
NC_015696:1749863:176159817615981761948351Francisella sp. TX077308 chromosome, complete genomeputative iron binding protein2e-1787.4
NC_006570:707280:720083720083720433351Francisella tularensis subsp. tularensis Schu 4, complete genomehypothetical protein2e-1787.4
NC_004556:1933944:193641719364171936803387Xylella fastidiosa Temecula1, complete genomeHesB-like protein5e-1786.3
NC_011184:2369662:239248123924812392822342Vibrio fischeri MJ11 chromosome I, complete sequenceiron-binding protein ErpA2e-1684.3
NC_013889:413909:419762419762420142381Thioalkalivibrio sp. K90mix chromosome, complete genomeiron-sulfur cluster assembly accessory protein4e-1683.2
NC_009654:1123709:112733911273391127686348Marinomonas sp. MWYL1, complete genomeiron-sulfur cluster assembly accessory protein5e-1683.2
NC_007984:221030:240709240709241056348Baumannia cicadellinicola str. Hc (Homalodisca coagulata), completeHesB family protein6e-1682.8
NC_008095:6253610:625409462540946254435342Myxococcus xanthus DK 1622, complete genomeiron-sulfur cluster assembly accessory protein4e-1580.1
NC_008789:942309:958205958205958576372Halorhodospira halophila SL1, complete genomeiron-sulfur cluster assembly accessory protein6e-1579.3
NC_010611:3879190:389703538970353897370336Acinetobacter baumannii ACICU, complete genomehypothetical protein9e-1579
NC_010410:11201:136801368014015336Acinetobacter baumannii AYE, complete genomeputative chaperone involved in Fe-S cluster assembly and activation (HesB-like)9e-1579
NC_014820:71565:105653105653106003351Cenarchaeum symbiosum A, complete genomehypothetical protein1e-1478.6
NC_010085:1174917:119326111932611193611351Nitrosopumilus maritimus SCM1, complete genomeiron-sulfur cluster assembly accessory protein5e-1476.6
NC_008576:3812500:382752338275233827864342Magnetococcus sp. MC-1, complete genomeiron-sulfur cluster assembly accessory protein1e-1374.7
NC_017505:1338661:135538113553811355761381Neisseria meningitidis alpha710 chromosome, complete genomeHesB-like protein7e-1372.8
NC_003116:1488576:150332215033221503642321Neisseria meningitidis Z2491, complete genomeHesB-like protein8e-1372.4
NC_013016:1257942:127529012752901275610321Neisseria meningitidis alpha14 chromosome, complete genomeHesB/YadR/YfhF family protein8e-1372.4
NC_017512:1264542:127928812792881279608321Neisseria meningitidis WUE 2594, complete genomeputative IscA-like protein8e-1372.4
NC_017516:917817:922502922502922822321Neisseria meningitidis H44/76 chromosome, complete genomeiron-sulfur cluster assembly protein IscA8e-1372.4
NC_017517:1377617:139368013936801394000321Neisseria meningitidis M01-240355 chromosome, complete genomeiron-sulfur cluster assembly protein IscA8e-1372.4
NC_010617:1428902:144458814445881444956369Kocuria rhizophila DC2201, complete genomeputative iron-sulfur cluster assembly protein IscA9e-1372
NC_008786:2687688:268768826876882688011324Verminephrobacter eiseniae EF01-2, complete genomeiron-sulfur cluster assembly protein IscA1e-1272
NC_017154:2901300:292316429231642923487324Yersinia pestis D106004 chromosome, complete genomeiron-sulfur cluster assembly protein1e-1272
NC_008150:2599661:262152426215242621847324Yersinia pestis Antiqua, complete genomehypothetical protein1e-1272
NC_013771:684966:704502704502704858357Cyanobacterium UCYN-A, complete genomeIron-sulfur cluster assembly accessory protein2e-1271.2
NC_002946:618439:622050622050622370321Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein2e-1271.2
NC_011035:1033942:105015510501551050535381Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeHesB/YadR/YfhF family protein2e-1271.2
NC_017511:950411:965950965950966330381Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomeHesB/YadR/YfhF family protein2e-1271.2
NC_014479:3079855:309420430942043094566363Bacillus subtilis subsp. spizizenii str. W23 chromosome, completeputative chaperone involved in Fe-S cluster assembly3e-1270.5
NC_013743:1937125:193995719399571940331375Haloterrigena turkmenica DSM 5511, complete genomeiron-sulfur cluster assembly accessory protein3e-1270.5
NC_014212:2776457:277792627779262778345420Meiothermus silvanus DSM 9946 chromosome, complete genomeiron-sulfur cluster assembly accessory protein3e-1270.5
NC_014210:3763940:377304337730433773390348Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,iron-sulfur cluster assembly accessory protein4e-1270.1
NC_012803:1302261:132118713211871321579393Micrococcus luteus NCTC 2665, complete genomeIron-sulfur cluster assembly accessory protein5e-1269.7
NC_015588:1965787:198187919818791982229351Isoptericola variabilis 225 chromosome, complete genomeiron-sulfur cluster assembly accessory protein9e-1268.9
NC_012526:2483000:249705424970542497476423Deinococcus deserti VCD115, complete genomeputative Iron-sulfur cluster biosynthesis protein IscA, putative HesB/YadR/YfhF protein family1e-1168.2
NC_013922:21000:237352373524109375Natrialba magadii ATCC 43099 chromosome, complete genomeiron-sulfur cluster assembly accessory protein1e-1168.2
NC_020388:693479:694398694398694757360Natronomonas moolapensis 8.8.11 complete genomeHesB/IscA family iron-sulfur cluster assembly accessory protein2e-1168.2
NC_015514:2414617:243305024330502433400351Cellulomonas fimi ATCC 484 chromosome, complete genomeiron-sulfur cluster assembly accessory protein2e-1167.8
NC_014248:685656:695087695087695419333Nostoc azollae 0708 chromosome, complete genomeiron-sulfur cluster assembly accessory protein2e-1167.8
NC_019974:1689486:169607116960711696445375Natronococcus occultus SP4, complete genomeIron-sulfur cluster assembly accessory protein2e-1167.8
NC_014958:66120:674696746967864396Deinococcus maricopensis DSM 21211 chromosome, complete genomeiron-sulfur cluster assembly accessory protein2e-1167.4
NC_021177:1922930:194284319428431943199357Streptomyces fulvissimus DSM 40593, complete genomeIron-sulfur cluster assembly accessory protein3e-1167
NC_015671:1540860:154610115461011546451351Cellvibrio gilvus ATCC 13127 chromosome, complete genomeiron-sulfur cluster assembly accessory protein3e-1167
NC_015731:2148517:217175121717512172101351Nitrosomonas sp. Is79A3 chromosome, complete genomeiron-sulfur cluster assembly accessory protein3e-1167
NC_019962:2189432:220476322047632205137375Natrinema pellirubrum DSM 15624, complete genomeIron-sulfur cluster assembly accessory protein3e-1167
NC_008278:7409711:740971174097117410289579Frankia alni ACN14a, complete genomeHypothetical protein in nifB-nifU intergenic region (ORF2)3e-1167
NC_015666:2721350:272181427218142722194381Halopiger xanaduensis SH-6 chromosome, complete genomeiron-sulfur cluster assembly accessory protein4e-1166.6
NC_010572:6293417:629486962948696295225357Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein4e-1166.6
NC_014151:2312000:232770523277052328055351Cellulomonas flavigena DSM 20109 chromosome, complete genomeiron-sulfur cluster assembly accessory protein5e-1166.2
NC_012559:2752825:276935227693522769675324Laribacter hongkongensis HLHK9, complete genomehypothetical protein6e-1166.2
NC_008025:316302:319325319325319747423Deinococcus geothermalis DSM 11300, complete genomeHesB/YadR/YfhF6e-1166.2
NC_007797:692944:697239697239697604366Anaplasma phagocytophilum HZ, complete genomeiron-sulfur cluster assembly accessory protein7e-1165.9
NC_015161:2018493:203259220325922033017426Deinococcus proteolyticus MRP chromosome, complete genomeiron-sulfur cluster assembly accessory protein1e-1065.5
NC_014963:113015:138363138363138830468Terriglobus saanensis SP1PR4 chromosome, complete genomeiron-sulfur cluster assembly accessory protein1e-1065.5
NC_009664:3718927:372491737249173725285369Kineococcus radiotolerans SRS30216, complete genomeiron-sulfur cluster assembly accessory protein9e-1165.5
NC_013169:1661135:167354816735481673907360Kytococcus sedentarius DSM 20547, complete genomeIron-sulfur cluster assembly accessory protein1e-1065.1
NC_014643:2056280:214296421429642143317354Rothia dentocariosa ATCC 17931 chromosome, complete genomeiron-sulfur cluster assembly protein IscA2e-1064.7
NC_009937:4122652:413900141390014139429429Azorhizobium caulinodans ORS 571, complete genomeHesB protein4e-1063.5
NC_007493:546000:546042546042546398357Rhodobacter sphaeroides 2.4.1 chromosome 1, complete sequenceProtein of unknown function, HesB/YadR/YfhF5e-1063.2
NC_008343:1470360:147162314716231472015393Granulibacter bethesdensis CGDNIH1, complete genomehesB protein family6e-1062.8
NC_015656:3300747:331807733180773318673597Frankia symbiont of Datisca glomerata chromosome, complete genomeiron-sulfur cluster assembly accessory protein6e-1062.8
NC_007354:534865:541851541851542306456Ehrlichia canis str. Jake, complete genomeHesB/YadR/YfhF6e-1062.8
NC_004369:2203947:221972722197272220191465Corynebacterium efficiens YS-314, complete genomehypothetical protein8e-1062.4
NC_016802:1615748:163086616308661631210345Corynebacterium diphtheriae HC02 chromosome, complete genomehypothetical protein8e-1062.4
NC_007413:1570000:158179815817981582136339Anabaena variabilis ATCC 29413, complete genomeHesB/YadR/YfhF1e-0962
NC_019771:2816732:282758028275802828074495Anabaena cylindrica PCC 7122, complete genomeiron-sulfur cluster assembly accessory protein1e-0961.6
NC_016632:830000:843589843589843954366Serratia symbiotica str. 'Cinara cedri' chromosome, completeFeS assembly scaffold protein2e-0961.6
NC_007799:686358:698929698929699381453Ehrlichia chaffeensis str. Arkansas, complete genomeiron-sulfur cluster assembly accessory protein2e-0961.2
NC_015167:1666000:169275816927581693087330Cellulophaga lytica DSM 7489 chromosome, complete genomeiron-sulfur cluster assembly accessory protein3e-0960.8
NC_011894:4066926:409218040921804092500321Methylobacterium nodulans ORS 2060, complete genomeiron-sulfur cluster assembly accessory protein2e-0960.8
NC_011658:4672000:469293646929364693289354Bacillus cereus AH187 chromosome, complete genomehesB/yadR/yfhF family protein3e-0960.5
NC_011969:4613430:463326646332664633658393Bacillus cereus Q1 chromosome, complete genomehesb/yadr/yfhf family protein3e-0960.5
NC_004463:1898648:191906519190651919385321Bradyrhizobium japonicum USDA 110, complete genomeR. etli iscN homolog3e-0960.5
NC_018750:2005229:201753520175352017891357Streptomyces venezuelae ATCC 10712, complete genomeprobable iron binding protein of the HesB_IscA_SufA family4e-0960.1
NC_009720:5079048:509887350988735099298426Xanthobacter autotrophicus Py2, complete genomeiron-sulfur cluster assembly accessory protein4e-0960.1
NC_019673:1656680:166804716680471668457411Saccharothrix espanaensis DSM 44229 complete genomeIron-sulfur cluster assembly accessory protein6e-0959.7
NC_010296:54000:760567605676379324Microcystis aeruginosa NIES-843, complete genomehypothetical protein6e-0959.7
NC_018750:2005229:202557420255742025930357Streptomyces venezuelae ATCC 10712, complete genomeprobable iron binding protein of the HesB_IscA_SufA family7e-0959.3
NC_019792:3735654:375320337532033753577375Natronobacterium gregoryi SP2 chromosome, complete genomeIron-sulfur cluster assembly accessory protein7e-0959.3
NC_003888:2305901:232436823243682324724357Streptomyces coelicolor A3(2), complete genomehypothetical protein7e-0959.3
NC_015953:1756493:177341417734141773770357Streptomyces sp. SirexAA-E chromosome, complete genomeiron-sulfur cluster assembly accessory protein1e-0858.5
NC_003272:5184000:519536351953635195701339Nostoc sp. PCC 7120, complete genomehypothetical protein1e-0858.5
NC_007484:1823751:184504218450421845365324Nitrosococcus oceani ATCC 19707, complete genomeHesB/YadR/YfhF2e-0754.7
NC_015277:6213304:265226523005354Sphingobacterium sp. 21 chromosome, complete genomeiron-sulfur cluster assembly accessory protein3e-0753.5
NC_007643:889755:898026898026898340315Rhodospirillum rubrum ATCC 11170, complete genomeHesB/YadR/YfhF5e-0753.1
NC_011726:1605600:161444116144411614770330Cyanothece sp. PCC 8801, complete genomeiron-sulfur cluster assembly accessory protein7e-0752.8
NC_008260:2142311:214573621457362146095360Alcanivorax borkumensis SK2, complete genomeiron-binding protein IscA1e-0652
NC_005295:647275:652681652681653142462Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein2e-0650.8
NC_006832:627057:632526632526632987462Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein2e-0650.8
NC_006831:622906:628377628377628838462Ehrlichia ruminantium str. Gardel, complete genomehypothetical protein2e-0650.8