Pre_GI: BLASTP Hits

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Query: NC_016911:771916:788390 Rickettsia rickettsii str. Hauke chromosome, complete genome

Start: 788390, End: 788605, Length: 216

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:772025:788499788499788714216Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein4e-33139
NC_016909:771542:788015788015788230216Rickettsia rickettsii str. Arizona chromosome, complete genomehypothetical protein4e-33139
NC_015866:767790:784092784092784307216Rickettsia heilongjiangensis 054 chromosome, complete genomehypothetical protein5e-30129
NC_013194:1631134:165527016552701656250981Candidatus Accumulibacter phosphatis clade IIA str. UW-1, completetransposase IS111A/IS1328/IS15332e-0754.3
NC_012912:3853377:388857638885763889544969Dickeya zeae Ech1591, complete genometransposase IS116/IS110/IS902 family protein3e-0753.9
NC_011000:2831183:285312128531212854086966Burkholderia cenocepacia J2315 chromosome 1, complete sequenceputative transposase6e-0752.8
NC_011283:1811000:187805818780581878648591Klebsiella pneumoniae 342 chromosome, complete genome9e-0752.4
NC_008786:3915000:391860239186023919564963Verminephrobacter eiseniae EF01-2, complete genometransposase IS116/IS110/IS902 family protein1e-0651.6
NC_008782:1483155:148843914884391489401963Acidovorax sp. JS42, complete genometransposase IS116/IS110/IS902 family protein2e-0651.2
NC_007517:3344799:336274733627473363703957Geobacter metallireducens GS-15, complete genomeIS111A/IS1328/IS1533/IS116/IS110/IS902 transposase2e-0651.2
NC_007517:3151742:317607231760723177028957Geobacter metallireducens GS-15, complete genomeIS111A/IS1328/IS1533/IS116/IS110/IS902 transposase2e-0651.2
NC_014314:1485500:150877615087761509729954Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completetransposase IS116/IS110/IS902 family protein2e-0650.8
NC_007712:254000:254988254988255872885Sodalis glossinidius str. 'morsitans', complete genometransposase4e-0650.1
NC_007712:532500:533223533223534044822Sodalis glossinidius str. 'morsitans', complete genometransposase4e-0650.1
NC_014228:3505320:350532035053203506207888Xenorhabdus nematophila ATCC 19061, complete genometransposase7e-0649.3