Pre_GI: BLASTP Hits

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Query: NC_016911:771916:783551 Rickettsia rickettsii str. Hauke chromosome, complete genome

Start: 783551, End: 783979, Length: 429

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:772025:783660783660784088429Rickettsia rickettsii str. Hino chromosome, complete genomeRrf2 family protein1e-78291
NC_016909:771542:783176783176783604429Rickettsia rickettsii str. Arizona chromosome, complete genomeRrf2 family protein1e-78291
NC_010263:771901:783536783536783964429Rickettsia rickettsii str. Iowa, complete genomeRrf2 family protein1e-78291
NC_015866:767790:779257779257779685429Rickettsia heilongjiangensis 054 chromosome, complete genomePutative transcriptional regulator4e-74275
NC_016050:771752:783334783334783762429Rickettsia japonica YH, complete genomeputative transcriptional regulator1e-73274
NC_007940:669143:672492672492672902411Rickettsia bellii RML369-C, complete genomePutative transcriptional regulator2e-59227
NC_009883:641491:644840644840645289450Rickettsia bellii OSU 85-389, complete genomePutative transcriptional regulator3e-59226
NC_011999:728353:735879735879736295417Macrococcus caseolyticus JCSC5402, complete genomehypothetical protein1e-25115
NC_015634:959396:984111984111984545435Bacillus coagulans 2-6 chromosome, complete genomeBadM/Rrf2 family transcriptional regulator4e-25113
NC_013446:2761000:276345027634502763896447Comamonas testosteroni CNB-2, complete genometranscriptional regulator, BadM/Rrf2 family2e-23107
NC_017059:2922000:294185829418582942292435Rhodospirillum photometricum DSM 122, complete genometranscriptional regulator4e-23106
NC_008577:44184:566305663057085456Shewanella sp. ANA-3 chromosome 1, complete sequencetranscriptional regulator, BadM/Rrf2 family3e-22103
NC_006510:1731939:176516917651691765612444Geobacillus kaustophilus HTA426, complete genomehypothetical protein3e-22103
NC_009720:3377071:337865933786593379108450Xanthobacter autotrophicus Py2, complete genomeBadM/Rrf2 family transcriptional regulator3e-21100
NC_006513:1695487:171563317156331716094462Azoarcus sp. EbN1, complete genomepredicted transcriptional regulator7e-2199
NC_006513:286549:309579309579310214636Azoarcus sp. EbN1, complete genomepredicted transcriptional regulator, rf2 family1e-2098.6
NC_013422:991500:997874997874998326453Halothiobacillus neapolitanus c2, complete genometranscriptional regulator, BadM/Rrf2 family1e-2098.2
NC_009254:745706:749444749444749956513Burkholderia vietnamiensis G4 chromosome 3, complete sequenceBadM/Rrf2 family transcriptional regulator1e-1994.7
NC_008209:761487:763317763317763787471Roseobacter denitrificans OCh 114, complete genomehypothetical protein1e-1891.7
NC_012808:3897751:390655139065513907027477Methylobacterium extorquens AM1, complete genometranscriptional regulator, rrf2 family3e-1787
NC_012988:4387735:439601743960174396493477Methylobacterium extorquens DM4, complete genomeRrf2 family transcriptional regulator3e-1787
NC_017167:2259413:226118022611802261467288Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1AsnC family transcriptional regulator3e-1684
NC_014394:808734:810507810507810938432Gallionella capsiferriformans ES-2 chromosome, complete genometranscriptional regulator, BadM/Rrf2 family3e-1580.5
NC_009077:1027357:102818110281811028642462Mycobacterium sp. JLS, complete genometranscriptional regulator, BadM/Rrf2 family6e-1579.7
NC_014210:3817948:383259538325953833026432Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,transcriptional regulator, BadM/Rrf2 family6e-1166.2
NC_006933:1051873:106659710665971067028432Brucella abortus biovar 1 str. 9-941 chromosome II, completeRfF2 family protein9e-1165.5
NC_003318:183914:187471187471187959489Brucella melitensis 16M chromosome II, complete sequenceRRF2 FAMILY PROTEIN1e-1065.1
NC_013385:1882549:190942419094241909837414Ammonifex degensii KC4, complete genometranscriptional regulator, BadM/Rrf2 family1e-1065.1
NC_010740:1051000:106578510657851066285501Brucella abortus S19 chromosome 2, complete sequenceRRF2 family protein1e-1065.1
NC_016642:1990684:199633319963331996725393Pseudovibrio sp. FO-BEG1 chromosome, complete genometranscriptional regulator, Rrf22e-1064.3
NC_010167:1287000:130504513050451305545501Brucella suis ATCC 23445 chromosome II, complete sequenceTranscriptional regulator, Rrf2 family protein5e-1063.2
NC_010104:1096081:111084711108471111347501Brucella canis ATCC 23365 chromosome II, complete sequencerrf2 family protein5e-1063.2
NC_012803:361127:379880379880380353474Micrococcus luteus NCTC 2665, complete genomerrf2 family protein, putative transcriptional regulator2e-0960.8
NC_013204:74855:100493100493100969477Eggerthella lenta DSM 2243, complete genometranscriptional regulator, BadM/Rrf2 family3e-0960.8
NC_011145:1435742:143574214357421436224483Anaeromyxobacter sp. K, complete genometranscriptional regulator, BadM/Rrf2 family6e-0959.3
NC_010718:304440:319008319008319475468Natranaerobius thermophilus JW/NM-WN-LF, complete genometranscriptional regulator, BadM/Rrf2 family7e-0959.3
NC_014551:483773:490676490676491179504Bacillus amyloliquefaciens DSM 7, complete genometranscriptional regulator9e-0958.9
NC_017188:461177:478328478328478831504Bacillus amyloliquefaciens TA208 chromosome, complete genometranscriptional regulator1e-0858.9
NC_009483:2489000:252245825224582522871414Geobacter uraniireducens Rf4 chromosome, complete genomeBadM/Rrf2 family transcriptional regulator1e-0858.5
NC_007760:2897409:291531029153102915789480Anaeromyxobacter dehalogenans 2CP-C, complete genometranscriptional regulator, BadM/Rrf2 family1e-0858.2
NC_009668:1591290:160547816054781605909432Ochrobactrum anthropi ATCC 49188 chromosome 2, complete sequenceBadM/Rrf2 family transcriptional regulator1e-0858.2
NC_011297:1357947:137869413786941379128435Dictyoglomus thermophilum H-6-12, complete genomeRRF2 protein family2e-0857.8
NC_011979:2892119:289631228963122896725414Geobacter sp. FRC-32, complete genometranscriptional regulator, BadM/Rrf2 family2e-0857.8
NC_020272:20435:261892618926692504Bacillus amyloliquefaciens IT-45, complete genomeHTH-type transcriptional regulator iscR4e-0857
NC_013766:679906:679906679906680322417Listeria monocytogenes 08-5578 chromosome, complete genomehypothetical protein5e-0856.6
NC_011761:2785660:282498828249882825428441Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completeRrf2 family protein6e-0856.2
NC_011206:2685499:272482727248272725267441Acidithiobacillus ferrooxidans ATCC 53993, complete genometranscriptional regulator, BadM/Rrf2 family6e-0856.2
NC_015589:2480365:248474324847432485153411Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeRrf2 family transcriptional regulator7e-0856.2
NC_007624:1046500:106138910613891061784396Brucella melitensis biovar Abortus 2308 chromosome II, completehypothetical protein8e-0855.8
NC_013118:1109610:112446011244601124855396Brucella microti CCM 4915 chromosome 2, complete genometranscriptional regulator, RrF2 family8e-0855.8
NC_015858:1150446:116507411650741165469396Brucella pinnipedialis B2/94 chromosome chromosome 2, completetranscriptional regulator, Rrf2 family protein8e-0855.8
NC_010001:1:114341143411871438Clostridium phytofermentans ISDg, complete genometranscriptional regulator, BadM/Rrf2 family1e-0755.1
NC_015589:626321:641545641545641970426Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeRrf2 family transcriptional regulator1e-0755.1
NC_010520:3674883:369132836913283691729402Clostridium botulinum A3 str. Loch Maree, complete genomeputative transcriptional regulator2e-0754.7
NC_012658:3678000:368338836833883683789402Clostridium botulinum Ba4 str. 657 chromosome, complete genomeRRF2 family protein3e-0753.9
NC_012034:1783912:180473918047391805191453Anaerocellum thermophilum DSM 6725, complete genometranscriptional regulator, BadM/Rrf2 family3e-0753.9
NC_007705:1388607:141460314146031415061459Xanthomonas oryzae pv. oryzae MAFF 311018, complete genomehypothetical protein3e-0753.9
NC_004311:1096649:111152111115211111916396Brucella suis 1330 chromosome II, complete sequenceRrF2 family protein3e-0753.9
NC_006834:1414113:144025714402571440715459Xanthomonas oryzae pv. oryzae KACC10331, complete genomehypothetical protein3e-0753.9
NC_009012:2953638:299313429931342993577444Clostridium thermocellum ATCC 27405, complete genometranscriptional regulator, BadM/Rrf2 family3e-0753.9
NC_014377:1089894:110347411034741103926453Thermosediminibacter oceani DSM 16646 chromosome, complete genometranscriptional regulator, BadM/Rrf2 family5e-0753.1
NC_013740:2141523:215595221559522156374423Acidaminococcus fermentans DSM 20731, complete genometranscriptional regulator, BadM/Rrf2 family8e-0752.4
NC_009437:2367842:238853223885322388984453Caldicellulosiruptor saccharolyticus DSM 8903, complete genomeBadM/Rrf2 family transcriptional regulator2e-0651.6
NC_011146:3537546:354820635482063548694489Geobacter bemidjiensis Bem, complete genometranscriptional regulator, BadM/Rrf2 family2e-0651.2
NC_013891:575746:587430587430587846417Listeria seeligeri serovar 1/2b str. SLCC3954, complete genomeRrf2 family transcriptional regulator protein3e-0650.8
NC_002946:618439:625195625195625641447Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein3e-0650.8
NC_011035:1033942:104694410469441047390447Neisseria gonorrhoeae NCCP11945 chromosome, complete genomePutative HTH-type transcriptional regulator NMB13783e-0650.8
NC_017511:950411:962769962769963215447Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein3e-0650.8
NC_014328:1307490:130946913094691309915447Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative transcriptional regulator3e-0650.8
NC_014652:1032711:105395410539541054406453Caldicellulosiruptor hydrothermalis 108 chromosome, completetranscriptional regulator, badm/rrf2 family3e-0650.8
NC_014657:1518721:153989615398961540348453Caldicellulosiruptor owensensis OL chromosome, complete genometranscriptional regulator, badm/rrf2 family3e-0650.8
NC_007907:5104476:510869651086965109076381Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-0650.8
NC_014963:113015:135717135717136211495Terriglobus saanensis SP1PR4 chromosome, complete genomeBadM/Rrf2 family transcriptional regulator3e-0650.4
NC_014721:1777644:179835917983591798811453Caldicellulosiruptor kristjanssonii 177R1B chromosome, completetranscriptional regulator, badm/rrf2 family3e-0650.4
NC_015949:1180755:120145512014551201907453Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomeBadM/Rrf2 family transcriptional regulator3e-0650.4
NC_016627:2524307:253149425314942531952459Clostridium clariflavum DSM 19732 chromosome, complete genomerrf2 family protein, putative transcriptional regulator4e-0650.1
NC_016627:2524307:253095125309512531400450Clostridium clariflavum DSM 19732 chromosome, complete genomerrf2 family protein, putative transcriptional regulator4e-0650.1
NC_008536:4921224:493025849302584930734477Solibacter usitatus Ellin6076, complete genometranscriptional regulator, BadM/Rrf2 family9e-0648.9