Pre_GI: BLASTP Hits

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Query: NC_016911:13826:29193 Rickettsia rickettsii str. Hauke chromosome, complete genome

Start: 29193, End: 29666, Length: 474

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:13826:292812928129754474Rickettsia rickettsii str. Hino chromosome, complete genomeF0F1 ATP synthase subunit B'3e-83306
NC_016913:1134000:113926111392611139734474Rickettsia rickettsii str. Brazil chromosome, complete genomeF0F1 ATP synthase subunit B'3e-83306
NC_016909:16465:291962919629669474Rickettsia rickettsii str. Arizona chromosome, complete genomeF0F1 ATP synthase subunit B'3e-83306
NC_016908:13826:292042920429677474Rickettsia rickettsii str. Colombia chromosome, complete genomeF0F1 ATP synthase subunit B'3e-83306
NC_009882:13826:292022920229675474Rickettsia rickettsii str. 'Sheila Smith', complete genomeF0F1 ATP synthase subunit B'3e-83306
NC_010263:13826:291942919429667474Rickettsia rickettsii str. Iowa, complete genomeATP synthase B' chain3e-83306
NC_016930:11721:274812748127954474Rickettsia philipii str. 364D chromosome, complete genomeF0F1 ATP synthase subunit B'2e-82303
NC_016915:13927:292412924129714474Rickettsia rickettsii str. Hlp#2 chromosome, complete genomeF0F1 ATP synthase subunit B'2e-82303
NC_003103:12114:266862668627159474Rickettsia conorii str. Malish 7, complete genomeATP synthase subunit B2e-81300
NC_016639:13188:299332993330406474Rickettsia slovaca 13-B chromosome, complete genomeATP synthase subunit B2e-81300
NC_017065:13188:299302993030403474Rickettsia slovaca str. D-CWPP chromosome, complete genomeF0F1 ATP synthase subunit B'2e-81300
NC_017044:15697:298032980330276474Rickettsia parkeri str. Portsmouth chromosome, complete genomeF0F1 ATP synthase subunit B'5e-81299
NC_012633:12000:265922659227065474Rickettsia africae ESF-5, complete genomeATP synthase B chain5e-81299
NC_016931:38350:514525145251925474Rickettsia massiliae str. AZT80 chromosome, complete genomeF0F1 ATP synthase subunit B'4e-80296
NC_017042:77363:821498214982622474Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, completeF0F1 ATP synthase subunit B'4e-80296
NC_016050:15224:300443004430517474Rickettsia japonica YH, complete genomeATP synthase subunit B2e-80296
NC_015866:14071:298892988930362474Rickettsia heilongjiangensis 054 chromosome, complete genomeF0F1 ATP synthase subunit B'6e-79292
NC_017028:109811:112876112876113349474Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completeF0F1 ATP synthase subunit B'6e-78288
NC_017043:735150:748743748743749225483Rickettsia montanensis str. OSU 85-930 chromosome, complete genomeF0F1 ATP synthase subunit B'4e-77286
NC_018720:1878201:188322918832291883774546Bifidobacterium asteroides PRL2011 chromosome, complete genomeATP synthase F0, B subunit2e-0651.2