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Query: NC_016911:13826:26068 Rickettsia rickettsii str. Hauke chromosome, complete genome

Start: 26068, End: 26172, Length: 105

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009882:13826:260532605326181129Rickettsia rickettsii str. 'Sheila Smith', complete genomehypothetical protein9e-1268.9
NC_010263:13826:260692606926173105Rickettsia rickettsii str. Iowa, complete genomehypothetical protein2e-1168.2
NC_016908:13826:260792607926183105Rickettsia rickettsii str. Colombia chromosome, complete genomehypothetical protein2e-1168.2
NC_016909:16465:260712607126175105Rickettsia rickettsii str. Arizona chromosome, complete genomehypothetical protein2e-1168.2
NC_016913:1134000:114276311427631142867105Rickettsia rickettsii str. Brazil chromosome, complete genomehypothetical protein2e-1168.2
NC_016914:13826:261562615626260105Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein2e-1168.2
NC_016930:11721:243562435624460105Rickettsia philipii str. 364D chromosome, complete genomehypothetical protein2e-1168.2
NC_016915:13927:261152611526219105Rickettsia rickettsii str. Hlp#2 chromosome, complete genomehypothetical protein5e-1166.6
NC_017028:109811:116782116782117360579Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completehypothetical protein1e-1065.5
NC_017044:15697:264172641726521105Rickettsia parkeri str. Portsmouth chromosome, complete genomehypothetical protein1e-1065.1
NC_017042:77363:861628616286494333Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, completehypothetical protein3e-1063.9
NC_015866:14071:266392663926797159Rickettsia heilongjiangensis 054 chromosome, complete genomehypothetical protein5e-0856.6