Pre_GI: BLASTP Hits

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Query: NC_016911:13826:20186 Rickettsia rickettsii str. Hauke chromosome, complete genome

Start: 20186, End: 25786, Length: 5601

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016909:16465:2018920189257895601Rickettsia rickettsii str. Arizona chromosome, complete genomecell surface antigen03286
NC_010263:13826:2018720187257875601Rickettsia rickettsii str. Iowa, complete genomehypothetical protein03286
NC_009882:13826:2019720197257975601Rickettsia rickettsii str. 'Sheila Smith', complete genomecell surface antigen03284
NC_016908:13826:2019720197257975601Rickettsia rickettsii str. Colombia chromosome, complete genomecell surface antigen03281
NC_016914:13826:2018720187258745688Rickettsia rickettsii str. Hino chromosome, complete genomecell surface antigen03269
NC_016913:1134000:1143149114314911486625514Rickettsia rickettsii str. Brazil chromosome, complete genomecell surface antigen03209
NC_016915:13927:2029920299258335535Rickettsia rickettsii str. Hlp#2 chromosome, complete genomecell surface antigen03165
NC_016930:11721:1852218522240745553Rickettsia philipii str. 364D chromosome, complete genomecell surface antigen03148
NC_003103:12114:1729817298230065709Rickettsia conorii str. Malish 7, complete genomecell surface antigen02977
NC_012633:12000:1734717347229145568Rickettsia africae ESF-5, complete genomeCell surface antigen Sca102931
NC_017065:13188:2051320513263385826Rickettsia slovaca str. D-CWPP chromosome, complete genomecell surface antigen02871
NC_016639:13188:2051620516263415826Rickettsia slovaca 13-B chromosome, complete genomeCell surface antigen Sca102871
NC_015866:14071:2027720277259405664Rickettsia heilongjiangensis 054 chromosome, complete genomecell surface antigen02844
NC_017044:15697:2040020400261355736Rickettsia parkeri str. Portsmouth chromosome, complete genomecell surface antigen01901
NC_016050:15224:2016520165260925928Rickettsia japonica YH, complete genomecell surface antigen sca101670
NC_016931:38350:4198041980472685289Rickettsia massiliae str. AZT80 chromosome, complete genomecell surface antigen Sca101538
NC_017042:77363:8704087040924845445Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, completecell surface antigen Sca101527
NC_017043:735150:7397617397617458686108Rickettsia montanensis str. OSU 85-930 chromosome, complete genomecell surface antigen01377
NC_017028:109811:1177081177081238366129Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completecell surface antigen01353
NC_017062:61500:6811968119730204902Rickettsia typhi str. B9991CWPP chromosome, complete genomehypothetical protein8e-51203
NC_017058:129474:1367501367501418045055Rickettsia australis str. Cutlack chromosome, complete genomehypothetical protein9e-51203
NC_017066:57571:6815268152726034452Rickettsia typhi str. TH1527 chromosome, complete genomehypothetical protein1e-50203
NC_006142:57571:6815268152726034452Rickettsia typhi str. Wilmington, complete genome190 kDa antigen precursor1e-50203
NC_009881:92929:1013311013311066645334Rickettsia akari str. Hartford, complete genome190 kDa antigen precursor1e-50202
NC_009881:92929:1071461071461125785433Rickettsia akari str. Hartford, complete genome190 kD antigen precursor3e-49198
NC_009882:100000:1074471074471129125466Rickettsia rickettsii str. 'Sheila Smith', complete genome190 kD antigen precursor4e-48195
NC_016914:99184:1075331075331130915559Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein4e-48195
NC_016908:100000:1074611074611129775517Rickettsia rickettsii str. Colombia chromosome, complete genomehypothetical protein4e-48195
NC_016909:100000:1074751074751129615487Rickettsia rickettsii str. Arizona chromosome, complete genomehypothetical protein4e-48195
NC_012633:98000:1052661052661110675802Rickettsia africae ESF-5, complete genomeCell surface antigen Sca22e-48195
NC_010263:100000:1074461074461130675622Rickettsia rickettsii str. Iowa, complete genomehypothetical protein4e-48194
NC_000963:83408:8907489074900991026Rickettsia prowazekii str. Madrid E, complete genome190 KD ANTIGEN PRECURSOR (sca2)8e-48193
NC_017062:547317:5568145568145638096996Rickettsia typhi str. B9991CWPP chromosome, complete genomecell surface antigen Sca34e-1895.5
NC_017051:878514:8785148785148834454932Rickettsia prowazekii str. Dachau chromosome, complete genomecell surface antigen (sca5)4e-1275.1
NC_007110:1:2224322243236731431Rickettsia felis URRWXCal2 plasmid pRF, complete sequenceCell surface antigen-like protein Sca127e-1274.7