Pre_GI: BLASTP Hits

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Query: NC_016908:926446:950991 Rickettsia rickettsii str. Colombia chromosome, complete genome

Start: 950991, End: 951563, Length: 573

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009882:915500:939881939881940453573Rickettsia rickettsii str. 'Sheila Smith', complete genomehypothetical protein2e-107387
NC_016911:926918:951463951463952035573Rickettsia rickettsii str. Hauke chromosome, complete genomehypothetical protein4e-107386
NC_016909:926000:951100951100951672573Rickettsia rickettsii str. Arizona chromosome, complete genomehypothetical protein4e-107386
NC_009900:1011000:103415110341511034726576Rickettsia massiliae MTU5, complete genomeNifU-like protein2e-97354
NC_017065:930985:952472952472953044573Rickettsia slovaca str. D-CWPP chromosome, complete genomeNifU-like protein3e-97353
NC_017042:1022112:104421010442101044782573Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, completeNifU-like protein4e-97353
NC_015866:933500:959209959209959781573Rickettsia heilongjiangensis 054 chromosome, complete genomeNifU-like protein1e-96351
NC_017043:376441:400494400494401066573Rickettsia montanensis str. OSU 85-930 chromosome, complete genomeNifU-like protein6e-96349
NC_017066:811565:835399835399835971573Rickettsia typhi str. TH1527 chromosome, complete genomehypothetical protein3e-93340
NC_017062:812133:835967835967836539573Rickettsia typhi str. B9991CWPP chromosome, complete genomehypothetical protein3e-93340
NC_006142:811469:835303835303835875573Rickettsia typhi str. Wilmington, complete genomehypothetical protein3e-93340
NC_000963:803435:826868826868827440573Rickettsia prowazekii str. Madrid E, complete genomehypothetical protein1e-92338
NC_017048:33578:570115701157583573Rickettsia prowazekii str. GvV257 chromosome, complete genomehypothetical protein1e-92338
NC_017049:801469:824902824902825474573Rickettsia prowazekii str. Chernikova chromosome, complete genomehypothetical protein1e-92338
NC_017050:804417:826780826780827352573Rickettsia prowazekii str. Katsinyian chromosome, complete genomehypothetical protein1e-92338
NC_017051:801488:824922824922825494573Rickettsia prowazekii str. Dachau chromosome, complete genomehypothetical protein1e-92338
NC_017056:804416:826779826779827351573Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomehypothetical protein1e-92338
NC_017057:804799:827162827162827734573Rickettsia prowazekii str. RpGvF24 chromosome, complete genomehypothetical protein1e-92338
NC_009879:860925:886866886866887435570Rickettsia canadensis str. McKiel, complete genomeNifU-like domain4e-89326
NC_009881:896007:922305922305922877573Rickettsia akari str. Hartford, complete genomehypothetical protein9e-86315
NC_020301:1449616:147054314705431471121579Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeNifU-related protein2e-48191
NC_010161:1811000:182998118299811830559579Bartonella tribocorum CIP 105476, complete genomeNifU-related protein5e-47186
NC_012846:1679184:169968516996851700263579Bartonella grahamii as4aup, complete genomenitrogen fixation protein1e-46185
NC_005955:1259393:127601012760101276588579Bartonella quintana str. Toulouse, complete genomehypothetical protein2e-45181
NC_015722:209722:223855223855224448594Candidatus Midichloria mitochondrii IricVA chromosome, completeNifU domain-containing protein7e-41166
NC_007799:186000:192635192635193195561Ehrlichia chaffeensis str. Arkansas, complete genomeNifU domain protein9e-39159
NC_012026:1034724:103663310366331037217585Anaplasma marginale str. Florida, complete genomehypothetical protein4e-38157
NC_004842:1031020:103290610329061033490585Anaplasma marginale str. St. Maries, complete genomehypothetical protein4e-38157
NC_005955:1259393:127658812765881276824237Bartonella quintana str. Toulouse, complete genome1e-1892.8
NC_005955:1259393:127682712768271277063237Bartonella quintana str. Toulouse, complete genome1e-1685.9
NC_015732:191554:204607204607204831225Spirochaeta caldaria DSM 7334 chromosome, complete genomenitrogen-fixing NifU domain-containing protein8e-1063.5
NC_021182:4310900:432688643268864327107222Clostridium pasteurianum BC1, complete genomethioredoxin-like protein2e-0962
NC_010546:553774:564649564649565530882Cyanothece sp. ATCC 51142 chromosome circular, complete sequenceiron-sulfur cluster assembly protein2e-0962
NC_005071:265520:287028287028287273246Prochlorococcus marinus str. MIT 9313, complete genomeNifU-like protein3e-0961.6
NC_011146:3206000:322418332241833224404222Geobacter bemidjiensis Bem, complete genomenitrogen-fixing NifU domain protein6e-0960.5
NC_012918:1660477:166429416642941664515222Geobacter sp. M21 chromosome, complete genomenitrogen-fixing NifU domain-containing protein1e-0859.7
NC_015578:3694813:371776537177653717989225Treponema primitia ZAS-2 chromosome, complete genomeiron-sulfur cluster-binding protein, Rieske family2e-0858.9
NC_014479:3079855:309925130992513099487237Bacillus subtilis subsp. spizizenii str. W23 chromosome, completeputative iron-sulfur scaffold protein2e-0858.5
NC_007575:319119:331292331292331567276Sulfurimonas denitrificans DSM 1251, complete genomenitrogen-fixing NifU-like protein2e-0755.5
NC_015312:6717973:673318367331836734103921Pseudonocardia dioxanivorans CB1190 chromosome, complete genomenitrogen-fixing NifU domain-containing protein5e-0754.3
NC_009662:222964:240586240586240888303Nitratiruptor sp. SB155-2, complete genomehypothetical protein6e-0753.9
NC_015873:380485:393292393292393591300Megasphaera elsdenii DSM 20460, complete genomenifU domain-containing protein1e-0653.1
NC_013730:1342500:135979713597971360063267Spirosoma linguale DSM 74, complete genomenitrogen-fixing NifU domain protein2e-0652.4
NC_008595:2687245:271930727193072720257951Mycobacterium avium 104, complete genomehypothetical protein2e-0652.4
NC_015656:3300747:331807733180773318673597Frankia symbiont of Datisca glomerata chromosome, complete genomeiron-sulfur cluster assembly accessory protein2e-0652.4
NC_008599:29000:478114781148077267Campylobacter fetus subsp. fetus 82-40, complete genomeNifU family protein3e-0651.6
NC_014960:3410741:342782234278223428091270Anaerolinea thermophila UNI-1, complete genomehypothetical protein4e-0651.2