Pre_GI: BLASTP Hits

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Query: NC_016908:926446:944075 Rickettsia rickettsii str. Colombia chromosome, complete genome

Start: 944075, End: 944160, Length: 86

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016930:943000:96108696108696117186Rickettsia philipii str. 364D chromosome, complete genometRNA-Tyr1e-0858.5
NC_009882:915500:93313093313093321586Rickettsia rickettsii str. 'Sheila Smith', complete genometRNA-Tyr1e-0858.5
NC_012730:1034115:10532681053268105335386Rickettsia peacockii str. Rustic, complete genometRNA-Tyr1e-0858.5
NC_016909:926000:94418494418494426986Rickettsia rickettsii str. Arizona chromosome, complete genometRNA-Tyr1e-0858.5
NC_016911:926918:94454794454794463286Rickettsia rickettsii str. Hauke chromosome, complete genometRNA-Tyr1e-0858.5
NC_016913:232500:23632423632423640986Rickettsia rickettsii str. Brazil chromosome, complete genometRNA-Tyr1e-0858.5
NC_016914:926500:94466594466594475086Rickettsia rickettsii str. Hino chromosome, complete genometRNA-Tyr1e-0858.5
NC_016915:928000:94573494573494581986Rickettsia rickettsii str. Hlp#2 chromosome, complete genometRNA-Tyr1e-0858.5
NC_017028:1131896:11483091148309114839486Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completetRNA-Tyr3e-0857.4
NC_016931:513662:51872951872951881486Rickettsia massiliae str. AZT80 chromosome, complete genometRNA-Tyr3e-0857.4
NC_009881:896007:91551191551191559686Rickettsia akari str. Hartford, complete genometRNA-Tyr3e-0857.4
NC_007109:300991:30385030385030393586Rickettsia felis URRWXCal2, complete genometRNA-Tyr3e-0857.4
NC_009900:1011000:10272821027282102736786Rickettsia massiliae MTU5, complete genometRNA-Tyr3e-0857.4
NC_009883:383500:38684838684838693386Rickettsia bellii OSU 85-389, complete genometRNA-Tyr3e-0857.4
NC_016050:938000:95552595552595561086Rickettsia japonica YH, complete genometRNA-Tyr3e-0857.4
NC_007940:1138324:11553671155367115545286Rickettsia bellii RML369-C, complete genometRNA-Tyr3e-0857.4
NC_012633:928500:94599894599894608386Rickettsia africae ESF-5, complete genometRNA-Tyr3e-0857.4
NC_006142:811469:83007283007283015786Rickettsia typhi str. Wilmington, complete genometRNA-Tyr3e-0857.4
NC_015866:933500:95226695226695235186Rickettsia heilongjiangensis 054 chromosome, complete genometRNA-Tyr3e-0857.4
NC_017042:1022112:10373621037362103744786Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, completetRNA-Tyr3e-0857.4
NC_017043:376441:39381039381039389586Rickettsia montanensis str. OSU 85-930 chromosome, complete genometRNA-Tyr3e-0857.4
NC_017044:954318:97165497165497173986Rickettsia parkeri str. Portsmouth chromosome, complete genometRNA-Tyr3e-0857.4
NC_017065:930985:94577594577594586086Rickettsia slovaca str. D-CWPP chromosome, complete genometRNA-Tyr3e-0857.4
NC_016639:930982:94577294577294585786Rickettsia slovaca 13-B chromosome, complete genometRNA-Tyr3e-0857.4
NC_017066:811565:83016883016883025386Rickettsia typhi str. TH1527 chromosome, complete genometRNA-Tyr3e-0857.4
NC_017062:812133:83073683073683082186Rickettsia typhi str. B9991CWPP chromosome, complete genometRNA-Tyr3e-0857.4
NC_017058:497500:50083150083150091686Rickettsia australis str. Cutlack chromosome, complete genometRNA-Tyr3e-0857.4
NC_017057:804799:82220082220082228586Rickettsia prowazekii str. RpGvF24 chromosome, complete genometRNA-Tyr3e-0857.4
NC_017056:804416:82181782181782190286Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genometRNA-Tyr3e-0857.4
NC_017051:801488:81996081996082004586Rickettsia prowazekii str. Dachau chromosome, complete genometRNA-Tyr3e-0857.4
NC_017050:804417:82181882181882190386Rickettsia prowazekii str. Katsinyian chromosome, complete genometRNA-Tyr3e-0857.4
NC_017049:801469:81994081994082002586Rickettsia prowazekii str. Chernikova chromosome, complete genometRNA-Tyr3e-0857.4
NC_017048:33578:52049520495213486Rickettsia prowazekii str. GvV257 chromosome, complete genometRNA-Tyr3e-0857.4
NC_009879:860925:88041988041988050486Rickettsia canadensis str. McKiel, complete genometRNA-Tyr4e-0857
NC_003103:919000:93593893593893602083Rickettsia conorii str. Malish 7, complete genometRNA-Tyr9e-0855.5
NC_000963:803435:82190982190982199183Rickettsia prowazekii str. Madrid E, complete genome2e-0754.3