Pre_GI: BLASTP Hits

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Query: NC_016908:278457:289702 Rickettsia rickettsii str. Colombia chromosome, complete genome

Start: 289702, End: 290268, Length: 567

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:278500:289796289796290362567Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein3e-106383
NC_016913:859931:878829878829879395567Rickettsia rickettsii str. Brazil chromosome, complete genomehypothetical protein3e-106383
NC_016911:278415:289663289663290229567Rickettsia rickettsii str. Hauke chromosome, complete genomehypothetical protein3e-106383
NC_016909:278327:289575289575290141567Rickettsia rickettsii str. Arizona chromosome, complete genomehypothetical protein3e-106383
NC_009882:278384:289631289631290197567Rickettsia rickettsii str. 'Sheila Smith', complete genomehypothetical protein3e-106383
NC_010263:278463:289710289710290276567Rickettsia rickettsii str. Iowa, complete genomehypothetical protein3e-106383
NC_012730:293634:300540300540301106567Rickettsia peacockii str. Rustic, complete genomehypothetical protein1e-103374
NC_017065:274165:290478290478291155678Rickettsia slovaca str. D-CWPP chromosome, complete genomecapsular polysaccharide biosynthesis protein7e-102369
NC_016639:274157:290470290470291147678Rickettsia slovaca 13-B chromosome, complete genomecapsular polysaccharide biosynthesis protein7e-102369
NC_012633:276500:287733287733288403671Rickettsia africae ESF-5, complete genome4e-65247
NC_015676:1736375:1760001176000117611881188Methanosalsum zhilinae DSM 4017 chromosome, complete genomeCapsular polysaccharide biosynthesis protein6e-1477
NC_013743:3020687:3027913302791330290671155Haloterrigena turkmenica DSM 5511, complete genomeCapsular polysaccharide biosynthesis protein- like protein2e-1168.9
NC_008312:4731692:4749656474965647509121257Trichodesmium erythraeum IMS101, complete genomeCapsular polysaccharide biosynthesis protein-like9e-1063.2
NC_010475:1161000:1169466116946611706111146Synechococcus sp. PCC 7002, complete genomehypothetical protein1e-0962.8
NC_007677:771168:8067448067448079971254Salinibacter ruber DSM 13855, complete genomehypothetical protein2e-0962.4
NC_013158:1027015:1042073104207310431971125Halorhabdus utahensis DSM 12940, complete genomeCapsular polysaccharide biosynthesis protein- like protein2e-0962.4
NC_019792:2173865:2183231218323121845021272Natronobacterium gregoryi SP2 chromosome, complete genomehypothetical protein1e-0859.7
NC_014973:1257625:1258421125842112595421122Geobacter sp. M18 chromosome, complete genomeputative capsular polysaccharide biosynthesis protein3e-0858.2
NC_009481:82767:9189791897930811185Synechococcus sp. WH 7803 chromosome, complete genomehypothetical protein3e-0858.2
NC_011146:482440:5028735028735039911119Geobacter bemidjiensis Bem, complete genomeputative capsular polysaccharide biosynthesis protein4e-0857.8
NC_019962:960831:9720349720349732541221Natrinema pellirubrum DSM 15624, complete genomehypothetical protein2e-0755.5
NC_019962:960831:9758749758749770821209Natrinema pellirubrum DSM 15624, complete genomehypothetical protein6e-0753.9
NC_016027:229180:2391332391332408721740Gluconacetobacter xylinus NBRC 3288, complete genomehypothetical protein7e-0753.5
NC_019964:1031660:1045957104595710471861230Halovivax ruber XH-70, complete genomehypothetical protein1e-0652.8
NC_013422:1604157:1616218161621816181101893Halothiobacillus neapolitanus c2, complete genomeCapsular polysaccharide biosynthesis protein-like protein2e-0652.4
NC_009831:3612206:3630106363010636316711566Shewanella sediminis HAW-EB3, complete genomehypothetical protein3e-0651.6
NC_009053:1785447:1805186180518618063341149Actinobacillus pleuropneumoniae L20, complete genomeregion 2 capsular polysaccharide biosynthesis protein4e-0651.2