Pre_GI: BLASTP Hits

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Query: NC_016908:278457:283825 Rickettsia rickettsii str. Colombia chromosome, complete genome

Start: 283825, End: 284352, Length: 528

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017065:274165:284671284671285198528Rickettsia slovaca str. D-CWPP chromosome, complete genomepeptide deformylase1e-89328
NC_010263:278463:283833283833284360528Rickettsia rickettsii str. Iowa, complete genomepeptide deformylase1e-89328
NC_016909:278327:283698283698284225528Rickettsia rickettsii str. Arizona chromosome, complete genomepeptide deformylase1e-89328
NC_016911:278415:283786283786284313528Rickettsia rickettsii str. Hauke chromosome, complete genomepeptide deformylase1e-89328
NC_016914:278500:283919283919284446528Rickettsia rickettsii str. Hino chromosome, complete genomepeptide deformylase1e-89328
NC_012730:293634:306459306459306986528Rickettsia peacockii str. Rustic, complete genomepeptide deformylase1e-89328
NC_009882:278384:283754283754284281528Rickettsia rickettsii str. 'Sheila Smith', complete genomepeptide deformylase1e-89328
NC_016639:274157:284663284663285190528Rickettsia slovaca 13-B chromosome, complete genomePolypeptide deformylase1e-89328
NC_016913:859931:884745884745885272528Rickettsia rickettsii str. Brazil chromosome, complete genomepeptide deformylase1e-89328
NC_012633:276500:281890281890282417528Rickettsia africae ESF-5, complete genomePolypeptide deformylase6e-89326
NC_017044:278500:283988283988284515528Rickettsia parkeri str. Portsmouth chromosome, complete genomepeptide deformylase6e-89326
NC_003103:266013:279505279505280032528Rickettsia conorii str. Malish 7, complete genomepeptide deformylase4e-89326
NC_016915:278000:283468283468283995528Rickettsia rickettsii str. Hlp#2 chromosome, complete genomepeptide deformylase7e-89325
NC_017043:990395:100111710011171001644528Rickettsia montanensis str. OSU 85-930 chromosome, complete genomepeptide deformylase1e-87322
NC_015866:274550:285188285188285715528Rickettsia heilongjiangensis 054 chromosome, complete genomepeptide deformylase1e-87321
NC_016931:269537:276698276698277225528Rickettsia massiliae str. AZT80 chromosome, complete genomepeptide deformylase2e-86317
NC_009881:283500:285876285876286403528Rickettsia akari str. Hartford, complete genomepeptide deformylase5e-85312
NC_017058:1152361:116463611646361165163528Rickettsia australis str. Cutlack chromosome, complete genomepeptide deformylase9e-85311
NC_016929:258500:266645266645267172528Rickettsia canadensis str. CA410 chromosome, complete genomepeptide deformylase3e-79293
NC_009879:260000:266962266962267489528Rickettsia canadensis str. McKiel, complete genomepeptide deformylase3e-79293
NC_017066:243913:254069254069254596528Rickettsia typhi str. TH1527 chromosome, complete genomepeptide deformylase5e-78290
NC_017062:244330:254486254486255013528Rickettsia typhi str. B9991CWPP chromosome, complete genomepeptide deformylase5e-78290
NC_006142:243899:254055254055254582528Rickettsia typhi str. Wilmington, complete genomepeptide deformylase5e-78290
NC_007798:301456:320139320139320699561Neorickettsia sennetsu str. Miyayama, complete genomepeptide deformylase5e-40163
NC_013854:2714033:273246827324682732980513Azospirillum sp. B510, complete genomepeptide deformylase4e-35147
NC_006511:3364448:338332333833233383832510Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCpeptide deformylase1e-32139
NC_013282:3962188:397851939785193979052534Cronobacter turicensis, complete genomePeptide deformylase1e-32139
NC_002695:4153394:416870241687024169211510Escherichia coli O157:H7 str. Sakai, complete genomepeptide deformylase8e-33139
CP002185:3627992:364665936466593647168510Escherichia coli W, complete genomepeptide deformylase8e-33139
NC_004842:1081271:110137011013701101927558Anaplasma marginale str. St. Maries, complete genomeN-formylmethionylaminoacyl-tRNA deformylase7e-30129
NC_018604:838932:861197861197861730534Brachyspira pilosicoli WesB complete genomepeptide deformylase1e-29129
NC_015138:5276857:529789952978995298408510Acidovorax avenae subsp. avenae ATCC 19860 chromosome, completepeptide deformylase2e-29127
NC_008752:5213431:523272252327225233231510Acidovorax avenae subsp. citrulli AAC00-1, complete genomepeptide deformylase6e-29126
NC_005125:2366778:238806323880632388626564Gloeobacter violaceus PCC 7421, complete genomepeptide deformylase3e-28124
NC_008260:125500:142342142342142848507Alcanivorax borkumensis SK2, complete genomepeptide deformylase2e-27121
NC_011992:3615517:363469936346993635211513Acidovorax ebreus TPSY, complete genomepeptide deformylase2e-27121
NC_004545:499709:513039513039513521483Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genomepolypeptide deformylase2e-27121
NC_010410:3719599:373875537387553739285531Acinetobacter baumannii AYE, complete genomepeptide deformylase 1 (N-formylmethionylaminoacyl-tRNA deformylase, binds Zn(II))6e-27120
NC_010611:208268:210696210696211226531Acinetobacter baumannii ACICU, complete genomeN-formylmethionyl-tRNA deformylase6e-27120
NC_005061:214168:236304236304236831528Candidatus Blochmannia floridanus, complete genomepolypeptide deformylase5e-27120
NC_017256:545204:545917545917546432516Buchnera aphidicola str. Ak (Acyrthosiphon kondoi) chromosome,peptide deformylase5e-27120
NC_004061:540354:545791545791546294504Buchnera aphidicola str. Sg (Schizaphis graminum), complete genomepolypeptide deformylase3e-27120
NC_011978:699500:722238722238722732495Thermotoga neapolitana DSM 4359, complete genomePeptide deformylase3e-26117
NC_009484:464342:464962464962465528567Acidiphilium cryptum JF-5 chromosome, complete genomepeptide deformylase1e-25115
NC_015186:573289:573918573918574475558Acidiphilium multivorum AIU301, complete genomepeptide deformylase1e-25115
NC_011833:545713:546430546430546951522Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chromosome,peptide deformylase5e-25113
NC_014924:3065430:307355030735503074092543Pseudoxanthomonas suwonensis 11-1 chromosome, complete genomepeptide deformylase2e-24111
NC_012039:1399699:142201114220111422532522Campylobacter lari RM2100, complete genomepeptide deformylase5e-24110
NC_019970:1457794:145779414577941458273480Thermoanaerobacterium thermosaccharolyticum M0795, complete genomepeptide deformylase3e-23107
NC_008513:343540:354044354044354493450Buchnera aphidicola str. Cc (Cinara cedri), complete genomeDef6e-23107
NC_012440:585568:590444590444590974531Persephonella marina EX-H1, complete genomepeptide deformylase7e-23106
NC_011035:1974489:199596819959681996513546Neisseria gonorrhoeae NCCP11945 chromosome, complete genomepeptide deformylase1e-22105
NC_017511:1883663:190423819042381904783546Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomepeptide deformylase1e-22105
NC_003112:96815:118025118025118528504Neisseria meningitidis MC58, complete genomepeptide deformylase1e-22105
NC_008767:84950:106002106002106505504Neisseria meningitidis FAM18, complete genomepolypeptide deformylase1e-22105
NC_017501:96211:116370116370116873504Neisseria meningitidis 8013, complete genomepeptide deformylase (PDF; polypeptide deformylase)1e-22105
NC_017505:96293:116667116667117170504Neisseria meningitidis alpha710 chromosome, complete genomepolypeptide deformylase1e-22105
NC_017515:76861:124063124063124566504Neisseria meningitidis M04-240196 chromosome, complete genomepeptide deformylase1e-22105
NC_017516:96879:118089118089118592504Neisseria meningitidis H44/76 chromosome, complete genomepeptide deformylase1e-22105
NC_017517:98554:119526119526120029504Neisseria meningitidis M01-240355 chromosome, complete genomepeptide deformylase1e-22105
NC_017518:98639:119014119014119517504Neisseria meningitidis NZ-05/33 chromosome, complete genomepeptide deformylase1e-22105
NC_013192:171000:171005171005171523519Leptotrichia buccalis DSM 1135, complete genomepeptide deformylase6e-22103
NC_017095:1333810:134101513410151341515501Fervidobacterium pennivorans DSM 9078 chromosome, complete genomepeptide deformylase5e-22103
NC_019897:73957:124573124573125091519Thermobacillus composti KWC4 chromosome, complete genomepeptide deformylase2e-21101
NC_014376:2921769:294945029494502949941492Clostridium saccharolyticum WM1 chromosome, complete genomepeptide deformylase5e-21100
NC_015425:906969:921878921878922357480Clostridium botulinum BKT015925 chromosome, complete genomepeptide deformylase5e-21100
NC_007517:3751107:375343537534353753938504Geobacter metallireducens GS-15, complete genomeFormylmethionine deformylase9e-2199.8
NC_008593:841291:856270856270856746477Clostridium novyi NT, complete genomepeptide deformylase1e-2099
NC_013132:6385223:639321763932176393792576Chitinophaga pinensis DSM 2588, complete genomepeptide deformylase2e-2098.2
NC_015953:4908069:493009249300924930730639Streptomyces sp. SirexAA-E chromosome, complete genomepeptide deformylase9e-2096.3
NC_009012:686740:695212695212695724513Clostridium thermocellum ATCC 27405, complete genomepeptide deformylase2e-1995.1
NC_009718:1024000:104289810428981043410513Fervidobacterium nodosum Rt17-B1, complete genomepeptide deformylase3e-1994.7
NC_014314:576465:608919608919609443525Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completepeptide deformylase3e-1994.7
NC_014109:393500:416454416454416909456Candidatus Riesia pediculicola USDA chromosome, complete genomepeptide deformylase5e-1994
NC_017187:1580988:159849315984931599008516Arcobacter butzleri ED-1, complete genomepeptide deformylase6e-1993.6
NC_014004:66631:877158771588284570Candidatus Sulcia muelleri DMIN chromosome, complete genomepeptide deformylase2e-1892
NC_014643:1986440:198776619877661988338573Rothia dentocariosa ATCC 17931 chromosome, complete genomepeptide deformylase6e-1890.1
NC_014655:851381:856124856124856705582Leadbetterella byssophila DSM 17132 chromosome, complete genomepeptide deformylase3e-1788.2
NC_013889:2603914:260893026089302609466537Thioalkalivibrio sp. K90mix chromosome, complete genomepeptide deformylase3e-1787.8
NC_014210:2372813:238910423891042389763660Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,peptide deformylase1e-1685.5
NC_007947:1556437:157481815748181575351534Methylobacillus flagellatus KT, complete genomePeptide deformylase2e-1685.5
NC_013123:78786:104565104565105107543Candidatus Sulcia muelleri SMDSEM, complete genomepeptide deformylase2e-1684.7
NC_016799:1343020:136412013641201364629510Corynebacterium diphtheriae 31A chromosome, complete genomepeptide deformylase3e-1684.7
NC_016790:1259356:127546312754631275972510Corynebacterium diphtheriae VA01 chromosome, complete genomepeptide deformylase3e-1684.7
NC_016787:1276983:129808412980841298593510Corynebacterium diphtheriae HC03 chromosome, complete genomepeptide deformylase3e-1684.7
NC_016783:1313008:133296413329641333473510Corynebacterium diphtheriae INCA 402 chromosome, complete genomepeptide deformylase3e-1684.3
NC_002935:1315019:133497513349751335484510Corynebacterium diphtheriae NCTC 13129, complete genomepeptide deformylase3e-1684.3
NC_016789:1334514:135447213544721354981510Corynebacterium diphtheriae PW8 chromosome, complete genomepeptide deformylase5e-1684
NC_010520:2807429:283291628329162833452537Clostridium botulinum A3 str. Loch Maree, complete genomepeptide deformylase5e-1683.6
NC_009697:2680607:268476226847622685298537Clostridium botulinum A str. ATCC 19397 chromosome, completepeptide deformylase5e-1683.6
NC_014033:675626:692194692194692754561Prevotella ruminicola 23 chromosome, complete genomepeptide deformylase6e-1683.6
NC_008025:2407618:241301524130152413665651Deinococcus geothermalis DSM 11300, complete genomePeptide deformylase7e-1683.2
NC_012563:2979147:298582129858212986357537Clostridium botulinum A2 str. Kyoto, complete genomepeptide deformylase1e-1582.8
NC_010581:561579:576054576054576551498Beijerinckia indica subsp. indica ATCC 9039, complete genomepeptide deformylase3e-1581.6
NC_014391:3596812:361503836150383615541504Micromonospora aurantiaca ATCC 27029 chromosome, complete genomepeptide deformylase3e-1581.3
NC_014815:5603000:560875356087535609256504Micromonospora sp. L5 chromosome, complete genomepeptide deformylase3e-1581.3
NC_008261:2117207:212122021212202121687468Clostridium perfringens ATCC 13124, complete genomepolypeptide deformylase6e-1580.5
NC_003366:1901898:190591019059101906377468Clostridium perfringens str. 13, complete genomepolypeptide deformylase6e-1580.5
NC_015434:3581001:359845235984523598949498Verrucosispora maris AB-18-032 chromosome, complete genomepeptide deformylase8e-1579.7
NC_008027:4280000:430333243033324303868537Pseudomonas entomophila L48, complete genomepeptide deformylase 21e-1479.3
NC_011989:1638261:166424516642451664745501Agrobacterium vitis S4 chromosome 1, complete sequencepeptide deformylase7e-1476.6
NC_014371:177536:182944182944183504561Prevotella melaninogenica ATCC 25845 chromosome chromosome II,peptide deformylase9e-1476.3
NC_020126:5849483:586317358631735863775603Myxococcus stipitatus DSM 14675, complete genomepeptide deformylase9e-1476.3
NC_013440:8443451:845437984543798454894516Haliangium ochraceum DSM 14365, complete genomeformylmethionine deformylase4e-1270.9
NC_016048:2907702:292746729274672927877411Oscillibacter valericigenes Sjm18-20, complete genomepeptide deformylase8e-1269.7
NC_014655:2533929:253730625373062537962657Leadbetterella byssophila DSM 17132 chromosome, complete genomepeptide deformylase2e-1168.6
NC_012471:1197534:127764412776441278054411Streptococcus equi subsp. equi 4047, complete genomepeptide deformylase3e-1167.8
NC_008820:1659612:166494716649471665492546Prochlorococcus marinus str. MIT 9303, complete genomeFormylmethionine deformylase5e-1167
NC_016050:73993:778737787378547675Rickettsia japonica YH, complete genomepolypeptide deformylase9e-1166.2
NC_012730:411526:415312415312415986675Rickettsia peacockii str. Rustic, complete genomepeptide deformylase2e-1065.1
NC_003103:70000:726597265973333675Rickettsia conorii str. Malish 7, complete genomepolypeptide deformylase [EC:3.5.1.31]2e-1065.1
NC_009900:73804:761817618176879699Rickettsia massiliae MTU5, complete genomePolypeptide deformylase2e-1065.1
NC_014724:59000:653216532165734414Lactobacillus amylovorus GRL 1112 chromosome, complete genomepeptide deformylase4e-1064.3
NC_015214:48999:561175611756530414Lactobacillus acidophilus 30SC chromosome, complete genomepeptide deformylase4e-1064.3
NC_016931:107880:127501127501128175675Rickettsia massiliae str. AZT80 chromosome, complete genomepolypeptide deformylase8e-1063.2
NC_015656:105840:1068141068141084031590Frankia symbiont of Datisca glomerata chromosome, complete genomeXRE family transcriptional regulator9e-1063.2
NC_017078:179848:198530198530198943414Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC1,putative peptide deformylase1e-0962.8
NC_009706:2673906:272573827257382726313576Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein3e-0961.2
NC_013740:1081454:109316310931631093573411Acidaminococcus fermentans DSM 20731, complete genomeformylmethionine deformylase4e-0960.8
NC_018528:65000:718617186172274414Lactobacillus helveticus R0052 chromosome, complete genomepeptide deformylase4e-0960.8
NC_014391:6848475:6866830686683068683621533Micromonospora aurantiaca ATCC 27029 chromosome, complete genomeformylmethionine deformylase6e-0960.5
NC_010080:69000:754017540175814414Lactobacillus helveticus DPC 4571, complete genomePolypeptide deformylase8e-0960.1
NC_013174:650986:659817659817660554738Jonesia denitrificans DSM 20603, complete genomePeptide deformylase6e-0960.1
NC_011900:1451545:147245614724561472866411Streptococcus pneumoniae ATCC 700669, complete genomepeptide deformylase2e-0858.5
NC_008533:1380406:139994713999471400357411Streptococcus pneumoniae D39, complete genomepolypeptide deformylase2e-0858.5
NC_003098:1372875:139241613924161392826411Streptococcus pneumoniae R6, complete genomepeptide deformylase2e-0858.5
NC_012469:1403412:142081714208171421227411Streptococcus pneumoniae Taiwan19F-14, complete genomepolypeptide deformylase2e-0858.5
NC_012466:1367099:138531413853141385724411Streptococcus pneumoniae JJA, complete genomepolypeptide deformylase2e-0858.5
NC_013204:929434:950025950025950435411Eggerthella lenta DSM 2243, complete genomeformylmethionine deformylase3e-0858.2
NC_013204:929434:956494956494956913420Eggerthella lenta DSM 2243, complete genomeformylmethionine deformylase3e-0857.8
NC_015434:6508500:6509904650990465114181515Verrucosispora maris AB-18-032 chromosome, complete genomeXRE family transcriptional regulator5e-0857.4
NC_014106:54587:614936149361906414Lactobacillus crispatus ST1, complete genomePeptide deformylase4e-0857.4
NC_004461:779000:781464781464782015552Staphylococcus epidermidis ATCC 12228, complete genomepeptide deformylase8e-0856.6
NC_017316:2466244:246624424662442466807564Enterococcus faecalis OG1RF chromosome, complete genomepeptide deformylase9e-0856.2
NC_004668:2938000:293813929381392938702564Enterococcus faecalis V583, complete genomepeptide deformylase9e-0856.2
NC_012468:1453763:147160514716051472015411Streptococcus pneumoniae 70585, complete genomepeptide deformylase1e-0756.2
NC_015957:8777644:8792053879205387935551503Streptomyces violaceusniger Tu 4113 chromosome, complete genomeXRE family transcriptional regulator1e-0755.8
NC_014169:1909482:193060019306001931004405Bifidobacterium longum subsp. longum JDM301 chromosome, completeformylmethionine deformylase5e-0753.9