Pre_GI: BLASTP Hits

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Query: NC_016845:1285435:1319864 Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,

Start: 1319864, End: 1320415, Length: 552

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011283:4170369:419877641987764199327552Klebsiella pneumoniae 342 chromosome, complete genomehypothetical protein2e-102370
NC_014121:3627588:364844936484493649000552Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completehypothetical protein7e-34143
NC_014640:4951076:495526949552694955802534Achromobacter xylosoxidans A8 chromosome, complete genomehypothetical protein4e-0960.8