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Query: NC_016845:1285435:1296112 Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,

Start: 1296112, End: 1296963, Length: 852

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_021066:2226826:224259322425932243426834Raoultella ornithinolytica B6, complete genomehypothetical protein2e-135481
NC_009778:2993218:301459530145953015491897Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein7e-87320
NC_009800:289000:302940302940303839900Escherichia coli HS, complete genomeputative replication protein O1e-77289
NC_013364:2645438:265048526504852651384900Escherichia coli O111:H- str. 11128, complete genomeputative replication protein1e-76286
NC_010067:2529750:258565725856572586556900Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein1e-64246
NC_006511:2501500:251508625150862515985900Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCDNA replication1e-63243
NC_011147:2496808:251062225106222511521900Salmonella enterica subsp. enterica serovar Paratyphi A strDNA replication1e-63243
NC_017328:303987:319215319215320105891Shigella flexneri 2002017 chromosome, complete genomeO protein2e-63242
NC_008258:269806:290308290308291132825Shigella flexneri 5 str. 8401, complete genomereplication protein O5e-59228
NC_013850:1887556:190154319015431902436894Klebsiella variicola At-22 chromosome, complete genomereplication protein O1e-57223
NC_014306:3524980:356534435653443566291948Erwinia billingiae Eb661, complete genomePhage replication protein O4e-53208
NC_015566:3659318:3659318365931836604151098Serratia sp. AS12 chromosome, complete genomephage O protein family1e-1583.6