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Query: NC_016845:1285435:1295618 Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,

Start: 1295618, End: 1295839, Length: 222

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_021066:2226826:224365222436522243873222Raoultella ornithinolytica B6, complete genomebacteriophage CII family protein6e-31132
NC_013850:1887556:190106119010611901360300Klebsiella variicola At-22 chromosome, complete genomeCII family protein2e-1477.8
NC_009778:2993218:301567830156783015956279Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein4e-0753.5
NC_007946:2625461:262931726293172629610294Escherichia coli UTI89, complete genomebacteriophage 343 regulatory protein CII6e-0752.8
NC_013008:306953:306953306953307246294Escherichia coli O157:H7 str. TW14359 chromosome, complete genomecII antiterminator protein for prophage CP-933H6e-0752.8
NC_002695:301939:303072303072303365294Escherichia coli O157:H7 str. Sakai, complete genomecII6e-0752.8
NC_002655:301940:303073303073303366294Escherichia coli O157:H7 EDL933, complete genomeputative cII antiterminator protein for prophage CP-933H6e-0752.8
NC_013361:3287671:329436532943653294643279Escherichia coli O26:H11 str. 11368 chromosome, complete genomephage regulatory protein CII7e-0649.3