Pre_GI: BLASTP Hits

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Query: NC_016822:3946500:3961033 Shigella sonnei 53G, complete genome

Start: 3961033, End: 3961605, Length: 573

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3655876:366890836689083669480573Shigella flexneri 2002017 chromosome, complete genomeacid-resistance membrane protein5e-85313
CP002516:246767:252727252727253299573Escherichia coli KO11, complete genomeacid-resistance membrane protein5e-85313
NC_000913:3624826:365501836550183655590573Escherichia coli K12, complete genomeacid-resistance membrane protein5e-85313
NC_010658:3622610:363479836347983635370573Shigella boydii CDC 3083-94, complete genomeputative HdeD protein5e-85313
NC_004337:3621985:363405236340523634624573Shigella flexneri 2a str. 301, complete genomehypothetical protein5e-85313
NC_004741:4132056:413922441392244139796573Shigella flexneri 2a str. 2457T, complete genomehypothetical protein5e-85313
NC_008258:3581583:359431335943133594885573Shigella flexneri 5 str. 8401, complete genomehypothetical protein5e-85313
CU928145:3983432:402210340221034022675573Escherichia coli 55989 chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_007613:3470314:350256135025613503133573Shigella boydii Sb227, complete genomehypothetical protein5e-85313
NC_009801:3956917:396880639688063969378573Escherichia coli E24377A, complete genomeputative HdeD protein5e-85313
NC_010468:231000:237088237088237660573Escherichia coli ATCC 8739, complete genomehypothetical protein5e-85313
CP002185:3822470:385277438527743853346573Escherichia coli W, complete genomeacid-resistance membrane protein5e-85313
AP010958:4313462:432420543242054324777573Escherichia coli O103:H2 str. 12009 DNA, complete genomeacid-resistance membrane protein HdeD5e-85313
AC_000091:3976888:398284839828483983420573Escherichia coli W3110 DNA, complete genomeacid-resistance membrane protein5e-85313
CU928160:3709081:372098037209803721552573Escherichia coli IAI1 chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_007384:3741708:374766837476683748240573Shigella sonnei Ss046, complete genomehypothetical protein5e-85313
NC_016902:246767:252727252727253299573Escherichia coli KO11FL chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_013364:4306000:431648443164844317056573Escherichia coli O111:H- str. 11128, complete genomeacid-resistance membrane protein HdeD5e-85313
NC_013361:4566779:457776445777644578336573Escherichia coli O26:H11 str. 11368 chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_013353:4313462:432420543242054324777573Escherichia coli O103:H2 str. 12009, complete genomeacid-resistance membrane protein HdeD5e-85313
NC_012967:3549880:358648635864863587058573Escherichia coli B str. REL606 chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_012947:248000:254118254118254690573Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeacid-resistance membrane protein5e-85313
NC_012759:3529657:354351235435123544084573Escherichia coli BW2952 chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_011741:3709081:372098037209803721552573Escherichia coli IAI1 chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_011748:3983432:402210340221034022675573Escherichia coli 55989, complete genomeacid-resistance membrane protein5e-85313
NC_004337:3590323:363405236340523634624573Shigella flexneri 2a str. 301, complete genomehypothetical protein5e-85313
NC_010473:3722571:375276337527633753335573Escherichia coli str. K-12 substr. DH10B, complete genomeacid-resistance membrane protein5e-85313
NC_009800:3685651:369830636983063698878573Escherichia coli HS, complete genomeputative HdeD protein5e-85313
NC_011415:3887997:390213739021373902709573Escherichia coli SE11 chromosome, complete genomeacid-resistance membrane protein5e-85313
NC_015224:3892972:391178239117823912354573Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,acid-resistance membrane protein2e-37154
NC_008800:4013298:403591840359184036490573Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,acid-resistance membrane protein8e-37153
NC_009832:4269804:427178342717834272352570Serratia proteamaculans 568, complete genomehypothetical protein2e-30131
NC_009648:3803622:384243438424343842931498Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeacid-resistance membrane protein8e-1166.6
NC_015566:4350080:435407143540714354475405Serratia sp. AS12 chromosome, complete genomehypothetical protein1e-0756.2