Pre_GI: BLASTP Hits

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Query: NC_016822:3946500:3960446 Shigella sonnei 53G, complete genome

Start: 3960446, End: 3960778, Length: 333

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3655876:366832136683213668653333Shigella flexneri 2002017 chromosome, complete genomeHns-dependent expression protein HdeA2e-39160
CP002516:246767:253554253554253886333Escherichia coli KO11, complete genomeHNS-dependent expression A2e-39160
NC_007613:3470314:350197435019743502306333Shigella boydii Sb227, complete genomehypothetical protein2e-39160
AC_000091:3976888:398367539836753984007333Escherichia coli W3110 DNA, complete genomestress response protein acid-resistance protein2e-39160
NC_004337:3621985:363346536334653633797333Shigella flexneri 2a str. 301, complete genomehypothetical protein2e-39160
NC_004741:4132056:414005141400514140383333Shigella flexneri 2a str. 2457T, complete genomehypothetical protein2e-39160
NC_008258:3581583:359372635937263594058333Shigella flexneri 5 str. 8401, complete genomehypothetical protein2e-39160
AP010958:4313462:432361843236184323950333Escherichia coli O103:H2 str. 12009 DNA, complete genomestress response protein acid-resistance protein HdeD2e-39160
CU928145:3983432:402151640215164021848333Escherichia coli 55989 chromosome, complete genomestress response protein acid-resistance protein2e-39160
NC_010658:3622610:363421136342113634543333Shigella boydii CDC 3083-94, complete genomehns-dependent expression protein A (HdeA)2e-39160
CP002185:3822470:385218738521873852519333Escherichia coli W, complete genomestress response protein acid-resistance protein2e-39160
NC_010473:3722571:375217637521763752508333Escherichia coli str. K-12 substr. DH10B, complete genomestress response protein acid-resistance protein2e-39160
NC_011748:3983432:402151640215164021848333Escherichia coli 55989, complete genomeacid-resistance protein2e-39160
NC_004337:3590323:363346536334653633797333Shigella flexneri 2a str. 301, complete genomehypothetical protein2e-39160
NC_000913:3624826:365443136544313654763333Escherichia coli K12, complete genomestress response protein acid-resistance protein2e-39160
NC_007384:3741708:374849537484953748827333Shigella sonnei Ss046, complete genomehypothetical protein2e-39160
NC_016902:246767:253554253554253886333Escherichia coli KO11FL chromosome, complete genomeHNS-dependent expression A2e-39160
NC_013364:4306000:431589743158974316229333Escherichia coli O111:H- str. 11128, complete genomestress response protein acid-resistance protein HdeD2e-39160
NC_013361:4566779:457717745771774577509333Escherichia coli O26:H11 str. 11368 chromosome, complete genomeacid-resistance protein2e-39160
NC_013353:4313462:432361843236184323950333Escherichia coli O103:H2 str. 12009, complete genomestress response protein acid-resistance protein HdeD2e-39160
NC_012967:3549880:358589935858993586231333Escherichia coli B str. REL606 chromosome, complete genomeacid-resistance protein2e-39160
NC_012947:248000:254945254945255277333Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeacid-resistance protein2e-39160
NC_012759:3529657:354292535429253543257333Escherichia coli BW2952 chromosome, complete genomeacid-resistance protein2e-39160
NC_011741:3709081:372039337203933720725333Escherichia coli IAI1 chromosome, complete genomeacid-resistance protein2e-39160
NC_011415:3887997:390155039015503901882333Escherichia coli SE11 chromosome, complete genomeacid-resistance protein2e-39160
CU928160:3709081:372039337203933720725333Escherichia coli IAI1 chromosome, complete genomestress response protein acid-resistance protein2e-39160
NC_009801:3956917:396821939682193968551333Escherichia coli E24377A, complete genomeprotein HdeA2e-39160
NC_009800:3685651:369771936977193698051333Escherichia coli HS, complete genomehns-dependent expression protein A (HdeA)2e-39160
NC_010468:231000:237915237915238247333Escherichia coli ATCC 8739, complete genomeHNS-dependent expression A2e-39160