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Query: NC_016822:3946500:3949432 Shigella sonnei 53G, complete genome

Start: 3949432, End: 3949710, Length: 279

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016902:246767:2583832583832593841002Escherichia coli KO11FL chromosome, complete genomepermease2e-33140
NC_010498:3838419:3862537386253738635381002Escherichia coli SMS-3-5, complete genomeputative permease2e-33140
NC_011415:3887997:3896056389605638970571002Escherichia coli SE11 chromosome, complete genomehypothetical protein2e-33140
NC_013361:4566779:4571679457167945726801002Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein2e-33140
CU928160:3709081:3714883371488337158961014Escherichia coli IAI1 chromosome, complete genomeputative membrane protein2e-33140
NC_011741:3709081:3714883371488337158961014Escherichia coli IAI1 chromosome, complete genomehypothetical protein2e-33140
CU928145:3983432:4015995401599540170201026Escherichia coli 55989 chromosome, complete genomeputative membrane protein2e-33140
NC_011748:3983432:4015995401599540170201026Escherichia coli 55989, complete genomehypothetical protein2e-33140
CP002185:3822470:3846689384668938476901002Escherichia coli W, complete genomeconserved hypothetical protein2e-33140
NC_009801:3956917:3962721396272139637221002Escherichia coli E24377A, complete genomeputative permease2e-33140
CP002516:246767:2583832583832593841002Escherichia coli KO11, complete genomepermease2e-33140
AP010958:4313462:4318121431812143191221002Escherichia coli O103:H2 str. 12009 DNA, complete genomeconserved predicted protein2e-33140
NC_013353:4313462:4318121431812143191221002Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein2e-33140
NC_017328:3655876:366286236628623663824963Shigella flexneri 2002017 chromosome, complete genomeputative membrane transport protein1e-25115
NC_008258:3581583:358826735882673589229963Shigella flexneri 5 str. 8401, complete genomehypothetical protein1e-25114
NC_013364:4306000:430912843091284310090963Escherichia coli O111:H- str. 11128, complete genomehypothetical protein1e-25114
NC_004741:4132056:414488041448804145836957Shigella flexneri 2a str. 2457T, complete genomehypothetical protein3e-24110
NC_004337:3621985:362801236280123628968957Shigella flexneri 2a str. 301, complete genomehypothetical protein3e-24110
NC_004337:3590323:362801236280123628968957Shigella flexneri 2a str. 301, complete genomehypothetical protein3e-24110
NC_014972:1407632:1435174143517414362711098Desulfobulbus propionicus DSM 2032 chromosome, complete genomepermease3e-1993.6
NC_008554:4699577:471204947120494712951903Syntrophobacter fumaroxidans MPOB, complete genomepermease2e-0754.7
NC_017281:1533454:153345415334541534401948Campylobacter jejuni subsp. jejuni S3 chromosome, complete genomemembrane protein8e-0649.3
NC_003912:1629937:162993716299371630884948Campylobacter jejuni RM1221, complete genomepermease, putative8e-0649.3