Pre_GI: BLASTP Hits

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Query: NC_016822:3923908:3940613 Shigella sonnei 53G, complete genome

Start: 3940613, End: 3941365, Length: 753

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
CP002185:3822470:383786038378603838612753Escherichia coli W, complete genomepredicted SAM-dependent methyltransferase4e-141500
NC_007384:3897000:391373239137323914484753Shigella sonnei Ss046, complete genomehypothetical protein4e-141500
NC_004741:4132056:415503041550304155782753Shigella flexneri 2a str. 2457T, complete genomehypothetical protein4e-141500
NC_011748:3983432:400718840071884007940753Escherichia coli 55989, complete genomeputative methyltransferase4e-141500
CU928145:3983432:400718840071884007940753Escherichia coli 55989 chromosome, complete genomeputative SAM-dependent methyltransferase4e-141500
NC_004337:3590323:361806636180663618818753Shigella flexneri 2a str. 301, complete genomehypothetical protein4e-141500
NC_010473:3722571:373814837381483738900753Escherichia coli str. K-12 substr. DH10B, complete genomepredicted SAM-dependent methyltransferase8e-141499
NC_010468:231000:250324250324251076753Escherichia coli ATCC 8739, complete genomeprotein of unknown function DUF5488e-141499
NC_007613:3470314:348734034873403488092753Shigella boydii Sb227, complete genomehypothetical protein8e-141499
NC_000913:3624826:364040336404033641155753Escherichia coli K12, complete genomepredicted SAM-dependent methyltransferase8e-141499
AC_000091:3995233:399728339972833998035753Escherichia coli W3110 DNA, complete genomepredicted SAM-dependent methyltransferase8e-141499
NC_010498:3838419:385380538538053854557753Escherichia coli SMS-3-5, complete genomehypothetical protein8e-141499
NC_011751:4074586:408997240899724090724753Escherichia coli UMN026 chromosome, complete genomeputative methyltransferase8e-141499
NC_012947:248000:267354267354268106753Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completemethyltransferase8e-141499
NC_012967:3549880:357307035730703573822753Escherichia coli B str. REL606 chromosome, complete genomeputative methyltransferase8e-141499
NC_013941:4249871:426528342652834266035753Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein8e-141499
NC_006905:3717306:371730637173063718064759Salmonella enterica subsp. enterica serovar Choleraesuis strputative SAM-dependent methyltransferase1e-135482
NC_014121:5000069:502181250218125022549738Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeputative methyltransferase3e-131467
NC_009778:4188000:419011741901174190869753Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein1e-124445
NC_010634:4463727:449636244963624497132771Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-103375
NC_009092:4337617:434887443488744349653780Shewanella loihica PV-4, complete genomeprotein of unknown function DUF5487e-84310
NC_009901:4899535:491611549161154916876762Shewanella pealeana ATCC 700345, complete genomeprotein of unknown function DUF5482e-79295
NC_013416:16493:330983309833856759Aggregatibacter actinomycetemcomitans D11S-1, complete genomeDNA polymerase I4e-76284
NC_012913:1867276:186944118694411870196756Aggregatibacter aphrophilus NJ8700, complete genomeDNA polymerase I5e-76284
NC_016513:317197:335475335475336167693Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeDNA polymerase I8e-72270
NC_010995:1139867:115746611574661158266801Cellvibrio japonicus Ueda107, complete genomehypothetical protein7e-49194
NC_014221:1167261:118301111830111183811801Truepera radiovictrix DSM 17093 chromosome, complete genomeprotein of unknown function DUF5481e-42173
NC_009667:1076718:109392110939211094538618Ochrobactrum anthropi ATCC 49188 chromosome 1, complete sequencehypothetical protein1e-35149
NC_003116:1734000:175083717508371751589753Neisseria meningitidis Z2491, complete genomehypothetical protein2e-33142