Pre_GI: BLASTP Hits

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Query: NC_016822:3923908:3938343 Shigella sonnei 53G, complete genome

Start: 3938343, End: 3938777, Length: 435

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013941:4249871:426301442630144263448435Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeuniversal stress protein A6e-80295
NC_004337:3590323:361579636157963616230435Shigella flexneri 2a str. 301, complete genomeuniversal stress protein6e-80295
NC_000913:3624826:363813436381343638568435Escherichia coli K12, complete genomeuniversal stress global response regulator6e-80295
AC_000091:3995233:399987039998704000304435Escherichia coli W3110 DNA, complete genomeuniversal stress global response regulator6e-80295
NC_007613:3470314:348507034850703485504435Shigella boydii Sb227, complete genomeuniversal stress protein6e-80295
NC_011748:3983432:400491840049184005352435Escherichia coli 55989, complete genomeuniversal stress global response regulator6e-80295
NC_008258:3550500:357635935763593576793435Shigella flexneri 5 str. 8401, complete genomeuniversal stress protein6e-80295
NC_010498:3838419:385153738515373851971435Escherichia coli SMS-3-5, complete genomeuniversal stress protein A6e-80295
NC_007384:3897000:391146239114623911896435Shigella sonnei Ss046, complete genomeuniversal stress protein6e-80295
CU928145:3983432:400491840049184005352435Escherichia coli 55989 chromosome, complete genomeuniversal stress global response regulator6e-80295
CP002185:3822470:383559038355903836024435Escherichia coli W, complete genomeuniversal stress global response regulator6e-80295
NC_010468:231000:252912252912253346435Escherichia coli ATCC 8739, complete genomeUspA domain protein6e-80295
NC_010473:3722571:373587937358793736313435Escherichia coli str. K-12 substr. DH10B, complete genomeuniversal stress global response regulator6e-80295
NC_011751:4074586:408770440877044088138435Escherichia coli UMN026 chromosome, complete genomeuniversal stress global response regulator6e-80295
NC_012947:248000:269942269942270376435Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeUspA domain protein6e-80295
NC_012967:3549880:357080035708003571234435Escherichia coli B str. REL606 chromosome, complete genomeuniversal stress global response regulator6e-80295
NC_014121:5000069:502128350212835021720438Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeuniversal stress protein A2e-78290
NC_009778:4188000:419096941909694191406438Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein4e-78289
NC_010634:4463727:449268044926804493126447Yersinia pseudotuberculosis PB1/+, complete genomeUspA domain-containing protein8e-75278
NC_020064:1962172:198734019873401987765426Serratia marcescens FGI94, complete genomeuniversal stress protein UspA-like protein1e-23108
NC_020064:2960332:298127429812742981699426Serratia marcescens FGI94, complete genomeuniversal stress family protein1e-22104
NC_015566:3269469:327324132732413273660420Serratia sp. AS12 chromosome, complete genomeUspA domain-containing protein2e-22104
NC_013457:140474:148863148863149252390Vibrio sp. Ex25 chromosome 2, complete genomeuniversal stress protein family 24e-2199.8
NC_020064:2960332:298083429808342981277444Serratia marcescens FGI94, complete genomeuniversal stress protein UspA-like protein6e-1889.4
NC_016816:4129299:416366041636604164085426Pantoea ananatis LMG 5342, complete genomeuniversal stress protein A3e-0650.4
NC_014304:77715:948169481695241426Erwinia billingiae Eb661 plasmid pEB102, complete sequenceUniversal stress protein A9e-0648.9