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Query: NC_016822:3923908:3937617 Shigella sonnei 53G, complete genome

Start: 3937617, End: 3937952, Length: 336

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013941:4249871:426228842622884262623336Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeuniversal stress protein B5e-60229
NC_010473:3722571:373515337351533735488336Escherichia coli str. K-12 substr. DH10B, complete genomepredicted universal stress (ethanol tolerance) protein B5e-60229
NC_011748:3983432:400419240041924004527336Escherichia coli 55989, complete genomeuniversal stress protein UspB5e-60229
AC_000091:3995233:400069540006954001030336Escherichia coli W3110 DNA, complete genomepredicted universal stress (ethanol tolerance) protein B5e-60229
NC_007384:3897000:391073639107363911071336Shigella sonnei Ss046, complete genomehypothetical protein5e-60229
CP002185:3822470:383486438348643835199336Escherichia coli W, complete genomepredicted universal stress (ethanol tolerance) protein B5e-60229
NC_000913:3624826:363740836374083637743336Escherichia coli K12, complete genomeuniversal stress protein UspB5e-60229
CU928145:3983432:400419240041924004527336Escherichia coli 55989 chromosome, complete genomeputative universal stress (ethanol tolerance) protein B5e-60229
NC_004337:3590323:361506736150673615402336Shigella flexneri 2a str. 301, complete genomeuniversal stress protein UspB5e-60229
NC_012967:3549880:357007435700743570409336Escherichia coli B str. REL606 chromosome, complete genomeuniversal stress protein UspB5e-60229
NC_012947:248000:270767270767271102336Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeuniversal stress protein UspB5e-60229
NC_007613:3470314:348434434843443484679336Shigella boydii Sb227, complete genomehypothetical protein5e-60229
NC_011751:4074586:408697840869784087313336Escherichia coli UMN026 chromosome, complete genomeuniversal stress protein UspB5e-60229
NC_008258:3550500:357563335756333575968336Shigella flexneri 5 str. 8401, complete genomehypothetical protein5e-60229
NC_009778:4188000:419180141918014192136336Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein5e-54209
NC_010634:4463727:449162044916204491955336Yersinia pseudotuberculosis PB1/+, complete genomeuniversal stress protein B1e-52204
NC_010498:3838419:385081138508113851092282Escherichia coli SMS-3-5, complete genomeuniversal stress protein B2e-49194
NC_014121:5000069:502066550206655020946282Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeuniversal stress protein UspB4e-45179