Pre_GI: BLASTP Hits

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Query: NC_016822:3065426:3076978 Shigella sonnei 53G, complete genome

Start: 3076978, End: 3077053, Length: 76

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011741:2818750:283036228303622830691330Escherichia coli IAI1 chromosome, complete genomehypothetical protein3e-0753.9
NC_011748:2973968:299614129961412996470330Escherichia coli 55989, complete genomehypothetical protein3e-0753.9
CU928145:2973968:299614129961412996470330Escherichia coli 55989 chromosome, complete genomeconserved hypothetical protein3e-0753.9
CU928160:2818750:283036228303622830691330Escherichia coli IAI1 chromosome, complete genomeconserved hypothetical protein3e-0753.9
CU928145:2973968:29963772996377299645276Escherichia coli 55989 chromosome, complete genometRNA-Met7e-0752.8
NC_004337:2747917:27583672758367275844276Shigella flexneri 2a str. 301, complete genometRNA-Met7e-0752.8
NC_000913:2746886:27837842783784278385976Escherichia coli K12, complete genometRNA-Ile7e-0752.8
NC_008258:2905413:29108252910825291090076Shigella flexneri 5 str. 8401, complete genometRNA-Met7e-0752.8
NC_009800:2788164:28032072803207280328276Escherichia coli HS, complete genometRNA-Met7e-0752.8
CU928160:2818750:28305982830598283067376Escherichia coli IAI1 chromosome, complete genometRNA-Met7e-0752.8
NC_004741:2741971:27530032753003275307876Shigella flexneri 2a str. 2457T, complete genometRNA-Ile7e-0752.8
NC_009801:2898426:29462862946286294636176Escherichia coli E24377A, complete genometRNA-Met7e-0752.8
NC_010468:1130000:11383331138333113840876Escherichia coli ATCC 8739, complete genometRNA-Met7e-0752.8
NC_012759:2633949:26695962669596266967176Escherichia coli BW2952 chromosome, complete genometRNA-Ile7e-0752.8
NC_011741:2818750:28305982830598283067376Escherichia coli IAI1 chromosome, complete genometRNA-Met7e-0752.8
NC_011748:2973968:29963772996377299645276Escherichia coli 55989, complete genometRNA-Met7e-0752.8
NC_010473:2839902:28755492875549287562476Escherichia coli str. K-12 substr. DH10B, complete genometRNA-Ile7e-0752.8
AC_000091:2747520:27844182784418278449376Escherichia coli W3110 DNA, complete genometRNA-Ile7e-0752.8
NC_007384:2933625:29454082945408294548376Shigella sonnei Ss046, complete genometRNA-Met7e-0752.8
NC_017328:2785309:27972522797252279732473Shigella flexneri 2002017 chromosome, complete genometRNA-Met2e-0650.8
NC_011750:2928990:295163029516302951959330Escherichia coli IAI39 chromosome, complete genomehypothetical protein3e-0650.4
NC_011750:2928990:29518662951866295194176Escherichia coli IAI39 chromosome, complete genometRNA-Met5e-0649.7
NC_010498:2847359:28593802859380285945576Escherichia coli SMS-3-5, complete genometRNA-Met5e-0649.7
NC_014618:690056:72577372577372584876Enterobacter cloacae SCF1 chromosome, complete genometRNA-Met5e-0649.7
NC_002655:3538656:35752373575237357531276Escherichia coli O157:H7 EDL933, complete genometRNA-Ile5e-0649.7
NC_002695:3468873:35079473507947350802276Escherichia coli O157:H7 str. Sakai, complete genometRNA-Ile5e-0649.7
NC_011353:3573641:36121833612183361225876Escherichia coli O157:H7 str. EC4115 chromosome, complete genometRNA-Met5e-0649.7
NC_013008:3525428:35669083566908356698376Escherichia coli O157:H7 str. TW14359 chromosome, complete genometRNA-Met5e-0649.7
NC_013941:3300000:33456913345691334576676Escherichia coli O55:H7 str. CB9615 chromosome, complete genometRNA-Met5e-0649.7
NC_011751:3048490:308901230890123089209198Escherichia coli UMN026 chromosome, complete genomehypothetical protein8e-0649.3