Pre_GI: BLASTP Hits

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Query: NC_016822:1818897:1826129 Shigella sonnei 53G, complete genome

Start: 1826129, End: 1827292, Length: 1164

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007384:1737885:1746807174680717479701164Shigella sonnei Ss046, complete genomehypothetical protein0694
NC_011750:1809943:1820681182068118219461266Escherichia coli IAI39 chromosome, complete genomehypothetical protein2e-130466
NC_010498:1700447:1707032170703217082911260Escherichia coli SMS-3-5, complete genomehypothetical protein2e-130465
NC_017328:1835108:184645018464501847439990Shigella flexneri 2002017 chromosome, complete genomehypothetical protein6e-97354
NC_008258:1784637:179323117932311794220990Shigella flexneri 5 str. 8401, complete genomeputative glycoportein6e-97354
NC_004337:1783645:179390717939071794896990Shigella flexneri 2a str. 301, complete genomeputative glycoprotein6e-97354
NC_004741:1823000:183085318308531831842990Shigella flexneri 2a str. 2457T, complete genomeputative glycoprotein6e-97354
NC_007606:1515403:1526379152637915274011023Shigella dysenteriae Sd197, complete genomehypothetical protein2e-91335
NC_004337:1783645:179331217933121793797486Shigella flexneri 2a str. 301, complete genomehypothetical protein4e-65248
NC_008258:1784637:179264217926421793121480Shigella flexneri 5 str. 8401, complete genomehypothetical protein1e-64247
NC_011353:1971145:198027919802791980782504Escherichia coli O157:H7 str. EC4115 chromosome, complete genome7e-63241
NC_002695:2056545:206567920656792066182504Escherichia coli O157:H7 str. Sakai, complete genomeIpaH-like protein7e-63241
NC_002655:2015000:202229120222912022794504Escherichia coli O157:H7 EDL933, complete genomehypothetical protein7e-63241
NC_013941:1857724:187014318701431870646504Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein2e-61236
NC_011750:1809943:1819362181936218206181257Escherichia coli IAI39 chromosome, complete genomehypothetical protein4e-45182
NC_010498:1700447:1708354170835417096101257Escherichia coli SMS-3-5, complete genomehypothetical protein4e-45182
NC_013941:1857724:1868066186806618693251260Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein5e-44178
NC_011751:1714131:1739999173999917412941296Escherichia coli UMN026 chromosome, complete genomehypothetical protein1e-43177
NC_011353:1971145:1978202197820219794611260Escherichia coli O157:H7 str. EC4115 chromosome, complete genomeleucine-rich repeat protein8e-43174
NC_013008:1971662:1977178197717819784371260Escherichia coli O157:H7 str. TW14359 chromosome, complete genomenon-LEE-encoded type III effector9e-43174
NC_002695:2056545:2063602206360220648611260Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein9e-43174
NC_002655:2015000:2023612202361220248711260Escherichia coli O157:H7 EDL933, complete genomehypothetical protein9e-43174
NC_002695:2056545:206492420649242065592669Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein6e-42171
NC_011353:1971145:197952419795241980192669Escherichia coli O157:H7 str. EC4115 chromosome, complete genome6e-42171
NC_013008:1971662:197850019785001979168669Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein6e-42171
NC_013941:1857724:186938818693881870056669Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein6e-42171
NC_002655:2015000:202291720229172023549633Escherichia coli O157:H7 EDL933, complete genomehypothetical protein3e-34146
NC_002973:369650:3696503696503715061857Listeria monocytogenes str. 4b F2365, complete genomecell wall surface anchor family protein3e-1169.7
NC_013315:1707293:1727689172768917300882400Clostridium difficile CD196 chromosome, complete genomepenicillin-binding protein3e-0963.2
NC_015501:154590:1552031552031578692667Porphyromonas asaccharolytica DSM 20707 chromosome, completehypothetical protein4e-0756.2
NC_013768:29324:3482134821373762556Listeria monocytogenes 08-5923, complete genomehypothetical protein4e-0652.8
NC_013766:29324:3482134821373762556Listeria monocytogenes 08-5578 chromosome, complete genomehypothetical protein4e-0652.8
NC_015160:2418317:242934924293492430212864Odoribacter splanchnicus DSM 20712 chromosome, complete genomehypothetical protein4e-0652.8