Pre_GI: BLASTP Hits

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Query: NC_016822:1339058:1344255 Shigella sonnei 53G, complete genome

Start: 1344255, End: 1345505, Length: 1251

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007384:1355060:1361414136141413627091296Shigella sonnei Ss046, complete genomehypothetical protein0865
NC_011741:1978500:1999968199996820030423075Escherichia coli IAI1 chromosome, complete genomeputative alpha-mannosidase0847
CU928160:1978500:1999968199996820030423075Escherichia coli IAI1 chromosome, complete genomeputative Alpha-mannosidase0847
NC_013364:2355298:2376735237673523798093075Escherichia coli O111:H- str. 11128, complete genomeputative alpha-D-mannosidase0811
NC_013361:2591829:2613266261326626161272862Escherichia coli O26:H11 str. 11368 chromosome, complete genomealpha-D-mannosidase0746
NC_009523:1746725:1746725174672517498983174Roseiflexus sp. RS-1 chromosome, complete genomeAlpha-mannosidase1e-56220
NC_006510:1921541:1935341193534119384753135Geobacillus kaustophilus HTA426, complete genomealpha-D-mannosidase1e-46187
NC_012589:2303096:2308639230863923116082970Sulfolobus islandicus L.S.2.15, complete genomeAlpha-mannosidase9e-38158
NC_017276:2080102:2085645208564520886142970Sulfolobus islandicus REY15A chromosome, complete genomeglycosyl hydrolase family protein1e-37157
NC_012623:355393:3683633683633713322970Sulfolobus islandicus Y.N.15.51 chromosome, complete genomeAlpha-mannosidase2e-37157
NC_017275:2176000:2208928220892822118972970Sulfolobus islandicus HVE10/4 chromosome, complete genomeglycosyl hydrolase family protein2e-37157
NC_012588:2173907:2179450217945021824192970Sulfolobus islandicus M.14.25 chromosome, complete genomeglycosyl hydrolase family protein4e-37155
NC_012726:2179085:2182123218212321850922970Sulfolobus islandicus M.16.4 chromosome, complete genome7e-37155
NC_012632:2279544:2285087228508722880562970Sulfolobus islandicus M.16.27 chromosome, complete genomeglycosyl hydrolase family protein1e-36154
NC_014537:2254061:2266902226690222698292928Vulcanisaeta distributa DSM 14429 chromosome, complete genomeglycoside hydrolase family 386e-36152
NC_021064:816000:8368308368308399133084Propionibacterium avidum 44067, complete genomealpha-mannosidase2e-33144
NC_014169:2353711:2360744236074423637733030Bifidobacterium longum subsp. longum JDM301 chromosome, completefamily 38 glycoside hydrolase1e-31137
NC_009954:117895:1218941218941250403147Caldivirga maquilingensis IC-167, complete genomeAlpha-mannosidase2e-31137
NC_013771:803042:8040538040538071453093Cyanobacterium UCYN-A, complete genomealpha-mannosidase1e-30134
NC_008698:1556223:1573072157307215761703099Thermofilum pendens Hrk 5, complete genomeglycoside hydrolase, family 382e-24113
NC_008618:1526392:1546291154629115495153225Bifidobacterium adolescentis ATCC 15703, complete genomealpha-mannosidase2e-1997.4
NC_017218:867550:8675508675508706993150Bifidobacterium breve ACS-071-V-Sch8b chromosome, complete genomeglycosyl hydrolase family 38, N-terminal domain protein3e-1790.1
NC_014205:1257652:1277116127711612796772562Staphylothermus hellenicus DSM 12710 chromosome, complete genomeAlpha-mannosidase3e-1686.7
NC_016935:2302055:2322140232214023245662427Paenibacillus mucilaginosus 3016 chromosome, complete genomeputative alpha-mannosidase2e-1273.9
NC_014377:532816:5509095509095535392631Thermosediminibacter oceani DSM 16646 chromosome, complete genomeAlpha-mannosidase3e-1273.2
NC_015690:1772015:1791993179199317944192427Paenibacillus mucilaginosus KNP414 chromosome, complete genomeputative alpha-mannosidase6e-1272.4
NC_017080:1335407:1338398133839813415053108Phycisphaera mikurensis NBRC 102666, complete genomealpha-mannosidase1e-0861.2
NC_002570:832480:8556588556588579912334Bacillus halodurans C-125, complete genomehypothetical protein2e-0757.8