Pre_GI: BLASTN Hits

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Query: NC_016768:1279178 Mycobacterium tuberculosis KZN 4207 chromosome, complete genome

Start: 1279178, End: 1300099, Length: 20922

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_000962:31168183116818313633319516Mycobacterium tuberculosis H37Rv, complete genome024740BLASTN svgBLASTP svg
NC_009525:31287863128786314904720262Mycobacterium tuberculosis H37Ra, complete genome024500BLASTN svgBLASTP svg
NC_009565:31280943128094314823720144Mycobacterium tuberculosis F11, complete genome023220BLASTN svgBLASTP svg
NC_002755:31109293110929312975718829Mycobacterium tuberculosis CDC1551, complete genome022490BLASTN svgBLASTP svg
NC_012207:30630393063039308477921741Mycobacterium bovis BCG str. Tokyo 172, complete genome022300BLASTN svgBLASTP svg
NC_008769:30702663070266308959919334Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome022300BLASTN svgBLASTP svg
NC_002945:30733703073370309459921230Mycobacterium bovis AF2122/97, complete genome022290BLASTN svgBLASTP svg
NC_019950:3139865*3139865316350123637Mycobacterium canettii CIPT 140060008 complete genome05539BLASTN svgBLASTP svg
NC_015848:31756923175692319911823427Mycobacterium canettii CIPT 140010059, complete genome05539BLASTN svgBLASTP svg
NC_009565:34857723485772350477419003Mycobacterium tuberculosis F11, complete genome02688BLASTN svgBLASTP svg
NC_009525:37940003794000381625122252Mycobacterium tuberculosis H37Ra, complete genome02686BLASTN svgBLASTP svg
NC_009525:2635792*2635792265864122850Mycobacterium tuberculosis H37Ra, complete genome02686BLASTN svgBLASTP svg
NC_000962:37815013781501380757326073Mycobacterium tuberculosis H37Rv, complete genome02686BLASTN svgBLASTP svg
NC_002755:47287247287249645723586Mycobacterium tuberculosis CDC1551, complete genome02678BLASTN svgBLASTP svg
NC_009077:2308634*2308634235649847865Mycobacterium sp. JLS, complete genome0779BLASTN svgBLASTP svg
NC_009525:83051383051384921918707Mycobacterium tuberculosis H37Ra, complete genome3e-21111BLASTN svgBLASTP svg
NC_002755:83139783139785005418658Mycobacterium tuberculosis CDC1551, complete genome2e-19105BLASTN svgBLASTP svg
NC_002945:83102983102985365622628Mycobacterium bovis AF2122/97, complete genome2e-19105BLASTN svgBLASTP svg
NC_008769:86067086067087969619027Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome2e-19105BLASTN svgBLASTP svg
NC_009565:83307683307685178218707Mycobacterium tuberculosis F11, complete genome2e-19105BLASTN svgBLASTP svg
NC_012207:83103083103085360922580Mycobacterium bovis BCG str. Tokyo 172, complete genome2e-19105BLASTN svgBLASTP svg
NC_008726:61000061000062882018821Mycobacterium vanbaalenii PYR-1, complete genome7e-19103BLASTN svgBLASTP svg
NC_008726:17761921776192180185525664Mycobacterium vanbaalenii PYR-1, complete genome7e-19103BLASTN svgBLASTP svg
NC_013235:2257899*2257899229859940701Nakamurella multipartita DSM 44233, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_013235:40911854091185411164620462Nakamurella multipartita DSM 44233, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_014814:42354774235477428692151445Mycobacterium sp. Spyr1 chromosome, complete genome4e-1797.6BLASTN svgBLASTP svg
NC_014814:2588628*2588628264757658949Mycobacterium sp. Spyr1 chromosome, complete genome4e-1797.6BLASTN svgBLASTP svg
NC_013235:3812838*3812838384142328586Nakamurella multipartita DSM 44233, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_013235:13544431354443137485420412Nakamurella multipartita DSM 44233, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_008435:1215437*1215437131209196655Rhodopseudomonas palustris BisA53, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014815:841484*84148489809956616Micromonospora sp. L5 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_015635:20015392001539201976918231Microlunatus phosphovorus NM-1, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_008752:32176953217695323954921855Acidovorax avenae subsp. citrulli AAC00-1, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_008752:29369332936933297832941397Acidovorax avenae subsp. citrulli AAC00-1, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_010125:10517351051735108259930865Gluconacetobacter diazotrophicus PAl 5, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014931:25114232511423253417122749Variovorax paradoxus EPS chromosome, complete genome1e-0560BLASTN svgBLASTP svg
NC_014931:29496972949697297109921403Variovorax paradoxus EPS chromosome, complete genome1e-0560BLASTN svgBLASTP svg
NC_014931:4210029*4210029424439734369Variovorax paradoxus EPS chromosome, complete genome1e-0560BLASTN svgBLASTP svg
NC_014931:4234288*4234288426496730680Variovorax paradoxus EPS chromosome, complete genome1e-0560BLASTN svgBLASTP svg
NC_014931:55739425573942559409920158Variovorax paradoxus EPS chromosome, complete genome1e-0560BLASTN svgBLASTP svg
NC_008314:1955793*1955793197880923017Ralstonia eutropha H16 chromosome 2, complete sequence1e-0560BLASTN svgBLASTP svg